I stumbled upon this article couple days ago that I thought the community might find interesting. According to this (and quite a few other articles) sublingual Salvinorin A is indistinguishable from placebo. In the case of this article up to 4mg!
link.springer.com
They talk about other articles with similar results, it seems only Ott has been able to get effects according to his research. With effects noticeable at 100ug.
This seems to directly contradict the numerous anecdotal reports regarding sublingual Salvia. Even ol Hamilton did it for the camera, and he looked proper fucked lol.
One thought that comes to mind is maybe the Salvinorin A is in a more sublingually bioavailable form in the plant/leaf. Or there’s other substances within the leaf that help improve BA.
What’s your thoughts? Who here’s tried Salvia sublingually? Even better who here’s tried it with high potency extracts?
-GC

Lack of effect of sublingual salvinorin A, a naturally occurring kappa opioid, in humans: a placebo-controlled trial - Psychopharmacology
Rationale Salvinorin A (SA) is a highly selective kappa opioid receptor agonist and the putative psychoactive compound in Salvia divinorum (SD), an increasingly abused hallucinogenic plant. Objectives The objectives of this study were to characterize the physiological and subjective effects of...

They talk about other articles with similar results, it seems only Ott has been able to get effects according to his research. With effects noticeable at 100ug.
This seems to directly contradict the numerous anecdotal reports regarding sublingual Salvia. Even ol Hamilton did it for the camera, and he looked proper fucked lol.
One thought that comes to mind is maybe the Salvinorin A is in a more sublingually bioavailable form in the plant/leaf. Or there’s other substances within the leaf that help improve BA.
What’s your thoughts? Who here’s tried Salvia sublingually? Even better who here’s tried it with high potency extracts?
-GC