First Off, try to find a psychedelic with no body load, this is the reason I have ordered 2c-C recently as I've heard many good things about it.
LSD doesnt seem to have any sort of funky bodyload till the last 2 hours or so, and is generally a non-bodyload drug for me.
DMT, you get used to the rush and it no longer becomes a body load after like the 5th time you do it.
etcetc
Take a benzo or something, it'll help with the bodyload, but it might put you out, and make your prolly well-paid-for trip, pretty useless.
Opiates prolly not a good idea as you'll just not feel great the next day and want more, but benzos can sometimes have the same reaction.
Cannabis helps, it may be a waste of money though as high grade cannabis costs a bit, and its not going to get you very high if youre already high as balls on a psychedelic.
As the feller above me said, Take a shower!!!
Showers are the best remedy for any bodyaches/pains or general discomfort.
I noticed someone also said Benedryl, not something I suggest, I feel as if it would make the trip worsen before it would even remotely sedate you. Most psyches KEEP YOU UP, and benzos RARELY can completely snuff a trip, now imagine being on diphenhydramine (benedryl) which people normally abuse and stay awake on for effects, well the psyche wont let you sleep, and now youre all dissociated on diphendydramine as well.
I also positively HATE the effects of diphenhydramine, makes me skitso or something, and always has a shitty hangover, like DxM.