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🌟🌟 Social 🌟🌟 Rectify's molecular poetry thread

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Aren't They Talking About Another Chemical With The Same Name (2,4-D) But Different Structure Than Mine?
 
(6aR,9R)-9-diethylamino-7-methyl-6,6a,8,9-tetrahydro-4H-indolo%5b4,3-fg%5d-quinoline.png


OUR_DAILY_BREAD
(6aR,9R)-9-diethylamino-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]-5-quinoline

From LSD-025 Via The Hoffman Reaction, Using Br2 & -OH. Note The C=O Functional Group Is There In LSD-025 But Not In ODB. The Former Is An Amide. The Latter, An Amine.
 
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I call this one "knight one".

It doesn't really matter which one the isomers, if it is N-Me or if it is sesamol the basic concept is the beta-naphthyl group is critical.
 
"Note The Hoffman Only Works For Primary Amides." - Symth2

So Then One Would Do The Hoffman On LSA And Then Get N,N-diethyl-lyergamine (ODB) By Di-ethylating The 9-amine, All Without Alkylating The Indolic Nitrogen Of LSA.
 
Well the intermediate exists already in the literature:
pubchem.ncbi.nlm.nih.gov

9,10-Didehydro-6-methylergoline-8beta-amine

9,10-Didehydro-6-methylergoline-8beta-amine | C15H17N3 | CID 10537963 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
pubchem.ncbi.nlm.nih.gov pubchem.ncbi.nlm.nih.gov
This is a primary amine though. It is used to make Mesulergine & Metoquizine & Etisulergine & Disulergine. See for SDZ-208-912 also.
Terguride & Lysuride & Bromerguride & Proterguride are made from iso-lysergic acid.

You can see that it helps to use my database.
 
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3,4-methylenedioxy-1-allyl-benzene.png


SAFROLE
3,4-methylenedioxy-1-allyl-benzene

+ THF + HBr(g)

-->

3,4-methylenedioxy-1-(2-bromopropyl)-benzene.png


2-bromo-safrole

+ CH3NH2 + CH3OH

-->

3,4-methylenedioxy-1-(2-methylaminopropyl)-benzene.png


MDMA
3,4-methylenedioxy-1-(2-methylaminopropyl)-benzene

+ HCl (g) + THF or CH3CH2-O-CH2CH3

--> MDMA.hcl

By Mouth Dosage: 70 to 150 mg of the hydrochloride salt

Duration: 3 to 6 hours

Fast, Aerobic Exercise With Loud, Repetitive Music Shown To Increase Ecstasy's Effects 7 Fold / 7x / 700%.

I Took It 200x (+/-) Before Developing A Perma Tolerance.
 
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Wacker Oxidation Of Myristicin

-->

1-(3,4-methylenedioxy-5-methoxyphenyl)-2-oxopropane.png


1-(3,4-methylenedioxy-5-methoxyphenyl)-2-oxopropane

-->

1-(3,4-methylenedioxy-5-methoxyphenyl)-2-hydroxylimino-propane.png


1-(3,4-methylenedioxy-5-methoxyphenyl)-2-hydroxylimino-propane

-->

1-(3,4-methylenedioxy-5-methoxyphenyl)-2-amino-propane.png


MMDA
1-(3,4-methylenedioxy-5-methoxyphenyl)-2-amino-propane
 
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(%e2%88%92)-(6aR,10aR)-6,6,9-trimethyl-1-methoxy-3-pentyl-6a,7,8,10a-tetrahydro-%206H-benzo%5bc%5dchromene.png


1-METHOXY_THC aka
"M-THC"
(%e2%88%92)-(6aR,10aR)-6,6,9-trimethyl-1-methoxy-3-pentyl-6a,7,8,10a-tetrahydro-%206H-benzo%5bc%5dchromene

Delta-9-THC + CH3OH + NaOCH3

--> "M-THC"

The Williamson Ether Synthesis

Even More Lipophilic Than Delta 9 THC, Whose Octanol : Water Coefficient Is Already 8000 : 1.
 
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1-methyl-6-aza-3-oxa-4-oxo-2-phenylcyclohexane.png


OXO_PRELUDIN (oxo-phenmetrazine)
1-methyl-6-aza-3-oxa-4-oxo-2-phenylcyclohexane
 
1-methyl-6-aza-3-oxa-4-oxo-2-(3,4-methylenedioxyphenyl)-cyclohexane.png


KARMA_CHAMELEON
1-methyl-6-aza-3-oxa-4-oxo-2-(3,4-methylenedioxyphenyl)-cyclohexane
 
Benzene.png


Benzene, C6H6

+

3-carboxymorpholine.png


3-carboxymorpholine

+ Hypophosphorous Acid, H4P2O6

-->

3-benzoylmorpholine.png


3-benzoylmorpholine

+ NaBH4

-->

1-phenyl-1-hydroxy-1-(3-morpholinyl)methane.png


1-phenyl-1-hydroxy-1-(3-morpholinyl)methane

+ Phosgene, Cl-(C=O)-Cl

-->

1-phenyl-1-chloro-1-(3-morpholinyl)methane.png


1-phenyl-1-chloro-1-(3-morpholinyl)methane

+ KCN

-->

1-phenyl-1-cyano-1-(3-morpholinyl)methane.png


1-phenyl-1-cyano-1-(3-morpholinyl)methane

+ H3O+

-->

1-phenyl-1-carboxy-1-(3-morpholinyl)methane.png


1-phenyl-1-carboxy-1-(3-morpholinyl)methane

+ HCl / CH3OH

-->

1-phenyl-1-carbomethoxy-1-(3-morpholinyl)methane.png


WALTER
1-phenyl-1-carbomethoxy-1-(3-morpholinyl)methane

* * *

Start With Toluene C6H5-CH3 Instead Of Benzene C6H6 And Get

1-(4-methylphenyl)-1-carbomethoxy-1-(3-morpholinyl)methane.png


MATILDA
1-(4-methylphenyl)-1-carbomethoxy-1-(3-morpholinyl)methane

Unlike The Original Synthesis Of MPH (methylphenidate; Ritalin), This Reaction Does NOT Require A Parr Hydrogenation Apparatus.
 
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