N&PD Moderators: Skorpio
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Smyth2
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This one reminds me of β-Phenylmethamphetamine.
ROCKET_SCIENCE
1,1-diphenyl-2-aminopropane
Or Is It?
The precursor for this is 1,1-Diphenylacetone and has dual use in the synthesis of Diphenadione.
α,α-DIPHENYLACETONE
Everett M. Schultz and Sally Mickey
Org. Synth. 1949, 29, 38
DOI: 10.15227/orgsyn.029.0038Smyth2
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1,1-Diphenyl-2-aminopropane
[3139-55-7]
An interesting analog I have in my database is where the benzhydryl group is in the form of a dibenzosuberane ring.
1-(2-Tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenyl)ethanamine
pubchem.ncbi.nlm.nih.gov
Winthrop, S. O.; Davis, M. A.; Myers, G. S.; Gavin, J. G.; Thomas, R.; Barber, R. (1962). "New Psychotropic Agents. Derivatives of Dibenzo[a,d]-1,4-cycloheptadiene". The Journal of Organic Chemistry 27: 230. doi:10.1021/jo01048a057.
If you read the above reference it does function as a stimulant but looks a bit goofy.
One thing I like about the dibenzosuberane ring is the versatility that can be offered wrt SAR studies.
For example consider the following compound:
https://pubchem.ncbi.nlm.nih.gov/compound/19079049
Werner Winter, et al. US4070373 (1978 to Roche Diagnostics GmbH).
This is a 2-MDP type hybrid idea.
I have the same compound minus the oxygen also:
Lettre Hans Dr Prof, et al. GB1129029 (1968 to Roche Diagnostics GmbH)
Hans Prof.Dr. 6900 Heidelberg Lettre, DE1568089 (1974 to Roche Diagnostics GmbH).Smyth2
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https://pubchem.ncbi.nlm.nih.gov/compound/27025

Robert B Moffett, US3325544 (1967 to Pharmacia and Upjohn Co).Rectify
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What Do I Mean By That? Well, (1) Human Beings Are Logical, AND (2) Human Beings Are Also NOT Logical.
Therefore, The Original Statement Is Both True AND False.Rectify
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ALEXANDER
N-allyl-1-phenyl-1-methoxy-2-aminopropane
Yes, I Tried It.
Yes, It Was Good.
BUT It Required High Doses, And I Thought I Might Could Smell My Brain Cells Burning After Being High On It For So Long, But Also Especially Because The 'Divine Or Nearly Divine' 5th Order N-allylic (R-NH-CH2CH=CH2) Amphetamines Require Large Doses And Take A While To Wear Off, Up To 4 Or 5 Days In My Case. (With Repeated Dosing)Smyth2
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[861007-01-4]
Tebbe olefination to mephedrone
See also: 1-Methyl-2-phenyl-allylamine.Smyth2
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Mehta Nariman Bomanshaw, Russell Peter Byrom, Baltzly Richard, US3065230 (1962 to Burroughs Wellcome Co).
Precursor: , GB948730 (1964 to Wellcome Foundation Ltd).Smyth2
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