N&PD Moderators: Skorpio
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Rectify
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EPHEDRINE
1-phenyl-1-hydroxy-2-methylaminopropane
1-phenyl-1-chloro-2-methylaminopropane
1-phenyl-1-cyano-2-methylaminopropane
1-phenyl-1-carboxy-2-methylaminopropane
1-phenyl-1-(hydroxymethyl)-2-methylaminopropane
VIOLA
1-phenyl-1-(2-oxapropyl)-2-methylaminopropaneSmyth2
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Good original idea. Except for the fact it has already been done before:
EPHEDRINE
1-phenyl-1-hydroxy-2-methylaminopropane
1-phenyl-1-chloro-2-methylaminopropane
1-phenyl-1-cyano-2-methylaminopropane
1-phenyl-1-carboxy-2-methylaminopropane
1-phenyl-1-(hydroxymethyl)-2-methylaminopropane
VIOLA
1-phenyl-1-(2-oxapropyl)-2-methylaminopropane
4-methoxy-N-methyl-3-phenylbutan-2-amine
pubchem.ncbi.nlm.nih.gov
Smyth2
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This was done by Howard M Deutsch already with 3',4'-Dichloro group.
SUPHENIDATE
1-phenyl-1-(methoxymethyl)-1-(piperidin-2-yl)-methane
2-[1-(3,4-Dichlorophenyl)-2-methoxyethyl]piperidine
pubchem.ncbi.nlm.nih.gov
You'd have thought some of these analogs work better than that new drug that got released (Serdexmethylphenidate).Smyth2
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Saitoh K, Abe K, Chiba T, Katagiri N, Saitoh T, Horiguchi Y, Nojima H, Taguchi K. Properties of 3-methyl-TIQ and 3-methyl-N-propargyl-TIQ for preventing MPTP-induced parkinsonism-like symptoms in mice. Pharmacol Rep. 2013;65(5):1204-12. doi: 10.1016/s1734-1140(13)71478-6. PMID: 24399716.
JAMES
2-aza-3-methyltetraline
Rectify
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Smyth2
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Smyth2
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