Taxil (Tropane-Paxil) (see under
RTI-274)
Image Taxil hosted in ImgBB
ibb.co
DAT = 3nM, NET = 2nM, SERT = 6nM.
Keverline-Frantz, Kathryn I.; Boja, John W.; Kuhar, Michael J.; Abraham, Philip; Burgess, Jason P.; Lewin, Anita H.; Carroll, F. Ivy (1998). "Synthesis and Ligand Binding of Tropane Ring Analogues of Paroxetine".
Journal of Medicinal Chemistry.
41 (2): 247–257.
doi:
10.1021/jm970669p.
Ogier L, Turpin F, Baldwin RM, Riché F, Law H, Innis RB, Tamagnan G (May 2002). "Rearrangement of a mesylate tropane intermediate in nucleophilic substitution reactions. Synthesis of aza-bicyclo[3.2.1]octane and aza-bicyclo[3.2.2]nonane ethers, imides, and amines".
The Journal of Organic Chemistry.
67 (11): 3637–42.
doi:
10.1021/jo010973x.
Runyon, Scott P.; Burgess, Jason P.; Abraham, Philip; Keverline-Frantz, Kathryn I.; Flippen-Anderson, Judy; Deschamps, Jeffrey; Lewin, Anita H.; Navarro, Hernán A.; Boja, John W.; Kuhar, Michael J.; Carroll, F. Ivy (2005). "Synthesis, structural identification, and ligand binding of tropane ring analogs of paroxetine and an unexpected aza-bicyclo[3.2.2]nonane rearrangement product".
Bioorganic & Medicinal Chemistry.
13 (7): 2439–2449.
doi:
10.1016/j.bmc.2005.01.046.