N&PD Moderators: Skorpio
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Smyth2
Bluelighter
No it exists all right. https://pubchem.ncbi.nlm.nih.gov/compound/14475299
TOM
N-ethynyl-1-phenyl-2-aminopropane
RICHARD
N-ethynyl-1-(4-methoxyphenyl)-2-aminopropane
HARRY
N-ethynyl-1-(3,4-methylenedioxyphenyl)-2-aminopropane
Are you batting for MAOI's like selegiline?4DQSAR
Bluelighter
Desmethylselegiline - Wikipedia
en.wikipedia.org
Fair to say it's in the public domain Well, the (R) enantiomer anyway.
Now it opens up some interesting questions. Does it blockade the tetrabenzapine (TBZ) and/or the reserpine site? Is the action of selegine partly mediated by desmethylsegeline with the medicine itself acting on the reserpine site but it's active metabolite action ad the TBZ site?
I'm sure the data is out there somewhere but I got to see the fallout 4MTA caused from close quarters so I'm extremely cautious when a design might possess significant MAOI activity. The (S) enatiomer may actually be more active BUT would also have 'side effects' like CNS stimulation. I don't know the answer to that either but the fact that from day one the medicine wasn't the raecemate does rather suggest that for whatever reasons, it was cosidered inferior... but who knows why?Rectify
Bluelighter
Are you batting for MAOI's like selegiline?
Not really. I took selegiline 1x and didn't feel much. More like looking for "barely legal" meth, pma, and mda. Each one of each I have had before but, for a variety of reasons, don't have now; mainly, penury and Schedule I status. (Schedule II in the case of meth, but although I did well on the MCAT, I am no medical doctor.)Rectify
Bluelighter
Desmethylselegiline - Wikipedia
en.wikipedia.org
The (S) enatiomer may actually be more active BUT would also have 'side effects' like CNS stimulation. I don't know the answer to that either but the fact that from day one the medicine wasn't the raecemate does rather suggest that for whatever reasons, it was cosidered inferior... but who knows why?
Because
(S)-SELEGILINE
N-methyl-N-(prop-2-ynyl)-1-phenyl-2-(2S)-methyl-2-aminoethane
Would Be Too Stimulating, Probably. Which Is Pretty Much What You Are Saying, I Think.