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🌟🌟 Social 🌟🌟 Rectify's molecular poetry thread

The 10 Step Outline:

3,4-dichlorobenzaldehyde.png


3,4-dichlorobenzaldehyde

-->

1-(3,4-dichlorophenyl)-2-nitro-prop-1-ene.png


1-(3,4-dichlorophenyl)-2-nitro-prop-1-ene

-->

1-(3,4-dichlorophenyl)-2-oxopropane.png


1-(3,4-dichlorophenyl)-2-oxopropane

-->

1-(3,4-dichlorophenyl)-2-oxo-1-bromopropane.png


1-(3,4-dichlorophenyl)-2-oxo-1-bromopropane

-->

Ketone protection with H+ and ethylene glycol, then treatment with NaCN, then deprotect spiro ketal with H+ to get the following ketone

-->

1-(3,4-dichlorophenyl)-1-cyano-2-oxopropane.png


1-(3,4-dichlorophenyl)-1-cyano-2-oxopropane

-->

1-(3,4-dichlorophenyl)-1-cyano-N-formyl-2-aminopropane.png


1-(3,4-dichlorophenyl)-1-cyano-N-formyl-2-aminopropane

plus anhydrous LAH and THF

-->

1-(3,4-dichlorophenyl)-1-carboxy-2-methylaminopropane.png


1-(3,4-dichlorophenyl)-1-carboxy-2-methylaminopropane

-->

1-(3,4-dichlorophenyl)-1-carbmethoxy-2-methylaminopropane.png


1-(3,4-dichlorophenyl)-1-carbomethoxy-2-methylaminopropane
 
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Sodium%204-pentylbenzoate.png


(n)-PENTYL-FEN
Sodium 4-pentylbenzoate

Non Steroidal Anti Inflammatory Drug (NSAID).
 
1-(4-pentyl-6-methoxy-2-hydroxyphenyl)-2-aminopropane.png


SPEEDY_GONZALES
1-(4-pentyl-6-methoxy-2-hydroxyphenyl)-2-aminopropane

1-phenyl-2-aminopropane.png


AUTOBOTS
1-phenyl-2-aminopropane

1-dimethylamino-2-(indole-3-yl)ethane.png


DECEPTICONS
1-dimethylamino-2-(indole-3-yl)-ethane

Don't Eat Me. Mainline Me!
Take Your Pic(k).

Remember, I See Everything Backwards.
 
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3-(oxomethyl)-indole.png


3-(oxomethyl)-indole

1-(indole-3-yl)-2-nitroethene.png


1-(indole-3-yl)-2-nitroethene
then NaBH4 in CH3OH

1-(indole-3-yl)-2-nitroethane.png


1-(indole-3-yl)-2-nitroethane
then the reflux of Sn roofing nails and aqueous HCl

1-(indole-3-yl)-2-aminoethane.png


1-(indole-3-yl)-2-aminoethane

Then triple exhaustive N-methylation with CH3I aka methyl iodide followed by reduction with LAH in THF per TiHKAL. Viola, DMT!
 
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1-(indole-3-yl)-1-oxo-2-diethylaminoethane.png


STEM_MULE_ANT
1-(indole-3-yl)-1-oxo-2-diethylaminoethane

Looking for a stimulant. Not sure what I'll find.
 
Possibly The Strongest Drug I Can Think Of.

5-(propylthio)-3-(2-diethylamino-1,2-dioxoethyl)-2-(piperonyl)-1-pentyl-indole.png


5-(propylthio)-3-(2-diethylamino-1,2-dioxoethyl)-2-(piperonyl)-1-pentyl-indole

Back 2 Life. Back To Reality.

3-(2-dimethylamino-ethyl)-2-(benzyl)-indole.png


TOP_OF_THE_LINE_DIME
3-(2-dimethylamino-ethyl)-2-(benzyl)-indole

3-(2-dimethylaminoethyl)-6-(2-aminopropyl)-indole.png


THE_CHAIN_GANG
3-(2-dimethylaminoethyl)-6-(2-aminopropyl)-indole

1-(4,7-dimethoxy-6-bromo-indole-3-yl)-2-amino-propane.png


SEX_ON_WHEELZ_OF_STEEL
1-(4,7-dimethoxy-6-bromo-indole-3-yl)-2-amino-propane

Now, Tell Me How You Feel.
 
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1-phenyl-1-carboethoxy-2-methylaminopropane.png


JON_SNOW
1-phenyl-1-carboethoxy-2-methylaminopropane

cyclopropyl%202-phenyl-3-ethylaminobutyrate.png


YANA_SOPHIA_EMORY
cyclopropyl 2-phenyl-3-ethylaminobutyrate

^-- from N-ethyl-PPA

1-phenyl-1-hydroxy-2-ethylaminopropane.png
 
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A Streamlined MPH Synthetic Outline:

1-phenyl-1-(2-piperidinyl)-methanone.png


1-phenyl-1-(2-piperidinyl)-methanone

-->

1-phenyl-1-(2-piperidinyl)-methanol.png


1-phenyl-1-(2-piperidinyl)-methanol

-->

1-phenyl-1-(2-piperidinyl)-1-chloro-methane.png


1-phenyl-1-(2-piperidinyl)-1-chloro-methane

-->

1-phenyl-1-(2-piperidinyl)-1-cyano-methane.png


1-phenyl-1-(2-piperidinyl)-1-cyano-methane

-->

1-phenyl-1-(2-piperidinyl)-1-carboxy-methane.png


1-phenyl-1-(2-piperidinyl)-1-carboxy-methane

-->

1-phenyl-1-(2-piperidinyl)-1-carbomethoxy-methane.png


1-phenyl-1-(2-piperidinyl)-1-carbomethoxy-methane; MPH; Ritalin. CII Controlled Substance.
 
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1-pentyl-2-benzyl-3-(2-dimethylamino-1-oxopropyl)-4-hydroxyindole.png


SIMPLY_JEFF
1-pentyl-2-benzyl-3-(2-dimethylamino-1-oxopropyl)-4-hydroxyindole

1-(indole-3-yl)-2-dimethylaminopropane.png


DAYTONA_MATTHEWS
1-(indole-3-yl)-2-dimethylaminopropane

from

3-(methanoneyl)indole.png


3-(methanone-yl)indole

The Darkest Minds (movie)
Heart Of Darkness by Joseph Conrad (book)
The Nappy Rootz, "Watermelon, Chicken, n Grits." (rap group)

1-(4-hydroxyindole-3-yl)-2-dimethylaminopropane.png


THE_MELLOW_MUSHROOM
1-(4-hydroxyindole-3-yl)-2-dimethylaminopropane

from

3-(methanoneyl)-4-hydroxyindole.png


3-(methanone-1-yl)-4-hydroxyindole
 
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What is Oma? I have never heard of it. Ortho-Methoxy-Amphetamine? What does it feel like?
 
Last edited:
I think this will work.

2-carboxypiperidine.png


2-carboxypiperidine

H3PO2

hypophosphorous acid

Benzene.png


benzene, C6H6

-->

1-phenyl-1-(2-piperidinyl)methanone.png


1-phenyl-1-(2-piperidinyl)methanone
MPH (methylphenidate) precursor
 
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1-(indole-3-yl)-1-carbomethoxy-1-(2-piperidinyl)-methane.png


DREAM_SO_REAL
1-(indole-3-yl)-1-carbomethoxy-1-(2-piperidinyl)-methane

1-(furan-2-yl)-2-aminopropane.png


L.O.V.E_TRACTOR
1-(furan-2-yl)-2-aminopropane
 
So, You Want To Roll HARD!?

1-(4-methoxyphenyl)-1-carbmethoxy-2-methylaminopropane.png


JENNIFER_ANISOLE
1-(4-methoxyphenyl)-1-carbmethoxy-2-methylaminopropane

from

1-(4-methoxyphenyl)-1-hydroxy-2-methylaminopropane.png


1-(4-methoxyphenyl)-1-hydroxy-2-methylaminopropane
 
1-(4-methoxyphenyl)-2-methylethene.png


1-(4-methoxyphenyl)-2-methylethene

(4-methoxy)-1-(methanone-yl)benzene.png


(4-methoxy)-1-(methanone-yl)benzene

1-(4-methoxyphenyl)-2-nitropropene.png


1-(4-methoxyphenyl)-2-nitropropene

1-(4-methoxyphenyl)-2-nitro-1-methoxypropane.png


1-(4-methoxyphenyl)-2-nitro-1-methoxypropane

1-(4-methoxyphenyl)-2-nitro-1-hydroxypropane.png


1-(4-methoxyphenyl)-2-nitro-1-hydroxypropane

1-(4-methoxyphenyl)-2-nitro-1-chloropropane.png


1-(4-methoxyphenyl)-2-nitro-1-chloropropane

1-(4-methoxyphenyl)-2-nitro-1-cyanopropane.png


1-(4-methoxyphenyl)-2-nitro-1-cyanopropane

1-(4-methoxyphenyl)-2-nitro-1-carboxypropane.png


1-(4-methoxyphenyl)-2-nitro-1-carboxypropane

1-(4-methoxyphenyl)-2-amino-1-carboxypropane.png


1-(4-methoxyphenyl)-2-amino-1-carboxypropane

1-(4-methoxyphenyl)-2-amino-1-carbomethoxypropane.png


1-(4-methoxyphenyl)-2-amino-1-carbomethoxypropane

1-(4-methoxyphenyl)-2-methylamino-1-carbomethoxypropane.png


1-(4-methoxyphenyl)-2-methylamino-1-carbomethoxypropane

Erm, This Is The Best Synthetic Outline I Could Come Up With Off The Top Of My Head. It Looks A Bit Labor Intensive. Your Constructive Feedback Is Always Welcome, Though.
 
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1-(4-methylphenyl)-1-carbomethoxy-1-(piperidine-2-yl)-methane.png


4-METHYL-METHYLIN
1-(4-methylphenyl)-1-carbomethoxy-1-(piperidine-2-yl)-methane

Start with toluene. If there is some 2 and/or 3-methylphenyl impurities in the final product, it's not going to hurt anything.
 
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