Diphenhydramine gives me restless leg syndrome, so I try to avoid it. Plus, in high doses it causes very creepy, uncomfortable trips.
I did doxylamine a few times but didn't notice much of an effect from it, good or bad.
I've only had promethazine mixed with codeine in cough syrup, so I'm not sure what it's like on its own.
They put me on a megadose of hydroxazine when I had chicken pox, but I don't remember any psychoactive effects from it. I was so uncomfortable from being sick that I don't think I would have even noticed.
Basically, anticholinergics/deliriants just aren't any fun. The only time I take them is in therapeutic doses when my allergies are acting up.
