Quickly Reducing Opiate Tolerance?

[tolerantmind]

Are there any ways that pain medication tolerance be quickly reduced other than just stopping the drug completely? I read something in an article about there being medications that can actually reset tolerance instantly. The article didn't name any of the medications though. There has to be a way to accelerate the loss of tolerance even while tapering off of a drug. Does anyone know of any methods or medications that can reduce tolerance quickly or even completely?

 

[Aether]

I believe NMDA agonists can reduce opiate tolerance.

 

[lazylazyjoe]

There is no miracle drug that will magically reset your tolerance (heard rumors ibogaine might, but never heard 1st hand report)f your just trying to get the most of your drug, you can always potentiate your use with an NMDA antagonist (Ketamine, Benzos) or antihistamines. Just remember to dose accordingly, as your risk of OD increases exponentially.
However, best way to lower your tolerance is to taper yourself down, then reuse (at a lower dose than normal ofcourse). Antagonists like naltrexone can speed up the process, but Precipitated WD is very unpleasant.
As far as I know, there is now way to get your tolerance lower than lowering your use or quitting. Your tolerance will never reset to the state from before you started, and there is nothing that will make it any lower once clean.
**As a post script , a good friend of mine told me that the best part of getting clean was the relapse...

 

[lorne667]

No, ibogaine is unfortunately bullshit. All it does is invoke a powerful psychadelic experience, which helps some people see within and finnaly WANT TO QIT. It effects physical symptoms. And there is now ay whatsoever to lower tolerance, except as lazylazyjoe said, by tapering down or just not using for a couple of days to help your receptors reset. NMDA antagonists don't reverse tolerance as far as I know; they help slow down, and in some cases almost completely stop the build up of tolerance, though if you combine tapering with NMDA antagonists you might achieve a similiar result.

In short, no, there is no "miracle drug" to stop things, the article was most likely misguided bullshit, like all the people who say ibogaine is a "miracle cure" that is illegal, when in reality it doesn't cure shit, and is illegal for a reason.Hope this helps

 

[tolerantmind]

I went back and reread the article and it said, "There are even some medications which can reset the nervous system completely, although medications like this are not made for all types of tolerances." So it's obvious that opiates are one of the tolerances that such a medication is not made for. I'm not a recreational user. I am prescribed medication for chronic pain. The problem with my situation is that my doctor who has me on pain management is not a pain doctor. He has very little knowledge about anything relating to the subject. I myself literally know more than he does that's how little he knows because it's simply not his field. I've gone to two different pain doctors and the first suggested switching from oxycodone to morphine sulfate ir. That was horrible as I went into withdrawal because the dosage of MS IR was nowhere near the dosage of Oxycodone IR I had been at. The second doctor just told me, "You're in the wrong place." I've begun tapering already. I'm just extremely frustrated as I haven't had true relief since the end of March. I'm a very atypical patient though according to all the specialists I've seen. My tolerance resets so quickly when I'm not on any medication. My body will reset in a week to exactly the way it was before I ever took anything. I'm extremely grateful for that. I just want to get to "ground zero" asap without causing myself too much torture as I'm already in a lot of pain anyway.

 

[Violenza666]

There really isn't going back to ground zero... Unless you've been off for years... I taper every month just so I can get some "feeling" too it.

 

[nsauce]

I have recently been doing research on Ibogaine, and it seems like there may be SOMETHING to it, but I think it is largely due to post-"trip" analysis of your experience, as directed by "specialists" to tailor-suit an interpretation. I do believe it helps some people, but I doubt it helps more than a LSD trip you can take on your own. I remember being pretty tranquil for a few days after heavily tripping (many years ago) and being inside the heart and mind of the universe so to speak. As I am currently having trouble with opioids, I found some pretty interesting interviews on youtube concerning this. If you want to have a look, just search youtube for "iboga experience" .

 

[OhSeeAT]

LORNE667 Have you ever done Ibogaine? Ibogaine does cure physical withdrawl when taken the proper dose, and a large amount of people who have done it, choose not to continue down their path of doing drugs.

I have a good friend who has had Ibogaine treatment for heroin addiction. He has done it twice, because of how spiritual and enlightening the first time was, and he remains clean. Ibogaine is on a whole other playing field than LSD, if you take LSD while withdrawling there's a very very good chance you are going to remain sick and have an overall shitty trip. Withdrawls are completely relieved upon taking Ibogaine. There's a big argument on why Ibogaine is illegal in the United States and legal in so many other countries. There is a lot of money in the addiction/treatment/drug court/prison/DEA system...

 

[tolerantmind]

There really isn't going back to ground zero... Unless you've been off for years... I taper every month just so I can get some "feeling" too it.

Yes, I'm fully aware how it is for most people. My body is very very different. I'm completely atypical medically. An example is this past spring my doctor messed up prescription directions and the directions read that I could take up to 12 Percocets a day when he actually wanted it to read for me to only take up to 10. So for a week I ended up having to go without anything at all. I'd been on daily pain medication for about 3 years at that point. So to begin I felt fine that week. I just had some body aches but nothing beyond that. I had a tylenol w/ codeine from awhile ago and at the end of the week I took it before I was about to get my next months Percocet prescription. The tylenol w/ codeine felt like the first time I took it. It completely got rid of my pain and just really really really had a strong effect. My doctor said I should've gone through a lot more than body pains and he said that the tylenol w/ codeine shouldn't have done squat for me. Multiple times I've reset myself and it's ALWAYS the same. My body goes back to square one. So much that I'll experience that first time flushing feeling when I do a reset. So that's why I'm saying I'm grateful because even my tolerance builds much slower than usual. I made the mistake of not doing a reset for awhile though. I'm anxious to see if I still completely reset in just a week. I've done it at various different levels but never this high up. I've seen a lot of doctors and they all ask if I'd want to possibly help other people by being studied and having some research done for awhile to see if they could possibly find out just exactly why my body acts this way. So in November I'm starting that. Hopefully they can figure out a way so that other people on pain medication can have that advantage. Good lord not even mentioning how all that Tylenol from the percocet didn't do anything to me. My liver numbers were fantastic. My doctor did some other tests and they all came back completely normal also. The sucky part of this is that 95% of the time the rules of medications or medical procedures don't apply to me. So doctors really don't know what to do with me or how to help me. I was hoping to find someone else like me on these boards. I'd laugh if it was all due to the insanely healthy diet I stick to.

 

[tolerantmind]

This can be closed. Th answer to my question has been answered by various posts. Thank you.

 

[effie]

Okay, no problem, glad you got your answer

Closed.