In the course of watching a fairly wide spectrum of people experiment with DPT some important aspects of the drug have become evident. There is a huge amount of variability in the dosage curve, physical effects, and subjective psychological response. Some people have been completely smashed with as little as 50 mg insufflated while others required 200 mg to really get where they wanted to go. Many people reported being uncomfortable with the physical aspect and body load that manifests as a very specific body vibration. It could be described as the classic kundalini archetype. There has been a wide variability with this, and the people who are more sensitive to the drug typically manifest more of the tremor effect. I have personally witnessed a hard core freak out with 60 mg insufflated and I feel obligated to strongly warn people about the serious nature of this drug. DPT is not for everybody, and certainly not for those just looking for a recreational good time.
There are several routes of administration which have varying time courses and effects. For the initial exploration of this substance I would strongly recommend starting with smoking small amounts of the freebase (20 mg) over the time course of 5 minutes. Smoking provides the fastest onset with almost immediate entry and a relatively short duration (20 minutes). This is by far the best way to learn DPT. Insufflation (Hcl salt) also works very well, but there is a much higher level commitment involved with a 2 hour duration. There are also distinct differences in the subjective effects of each route of administration. Among those who have experimented extensively with this substance the most direct and preferred route is intramuscular injection (Hcl salt). Most of the DPT we have seen available has been in the Hcl salt form and is not very efficient for smoking unless converted to freebase using standard kitchen chemistry basification methods. Although it was mentioned in TIHKAL that DPT is orally active, we found this route to be quite unpredictable when taking it without an MAOI. Recent reports indicate that propyl-huasca works very well using the standard amount of MAOI combined with 75-150 mg of DPT.
Again, we have observed that milage varies considerably from person to person with DPT. Some people were blown away with a lower end dosage level while others required two to five times as much to manifest the full effect. My advise is to work up gradually starting with a very low dosage level in order to acclimate yourself and then boost up as desired. There have been several major freak outs by those who chose to take the plunge and then could not handle the power of DPT.
