SNR
Bluelighter
- Joined
- Apr 20, 2011
- Messages
- 140
Hopefully bluelight merged my doublepost.. But anyways. Here's a list of selective and or high affinity ligands for the sigma 1 receptor. Maybe you would find it useful.
L-687,384
PRE-084: agonist
PD 144418
3-[[1-[(4-chlorophenyl)methyl]-4-piperidyl]methyl]-1,3-benzoxazol-2-one: very high affinity and subtype selectivity[17]
1'-[(4-fluorophenyl)methyl]spiro[1H-isobenzofuran-3,4'-piperidine][18]
1-benzyl-6′-methoxy-6′,7′-dihydrospiro[piperidine-4,4′-thieno[3.2-c]pyran]: putative antagonist, selective against 5-HT1A, 5-HT6, 5-HT7, α1A and α2 adrenergic, and NMDA receptors[19]
1'-benzyl-6-methoxy-1-phenyl-spiro[6H-furo[3,4-c]pyrazole-4,4'-piperidine][20]
(−)-(S)-4-methyl-1-[2-(4-chlorophenoxy)-1-methylethyl]piperidine[21]
L-687,384
PRE-084: agonist
PD 144418
3-[[1-[(4-chlorophenyl)methyl]-4-piperidyl]methyl]-1,3-benzoxazol-2-one: very high affinity and subtype selectivity[17]
1'-[(4-fluorophenyl)methyl]spiro[1H-isobenzofuran-3,4'-piperidine][18]
1-benzyl-6′-methoxy-6′,7′-dihydrospiro[piperidine-4,4′-thieno[3.2-c]pyran]: putative antagonist, selective against 5-HT1A, 5-HT6, 5-HT7, α1A and α2 adrenergic, and NMDA receptors[19]
1'-benzyl-6-methoxy-1-phenyl-spiro[6H-furo[3,4-c]pyrazole-4,4'-piperidine][20]
(−)-(S)-4-methyl-1-[2-(4-chlorophenoxy)-1-methylethyl]piperidine[21]
