• Select Your Topic Then Scroll Down
    Alcohol Bupe Benzos
    Cocaine Heroin Opioids
    RCs Stimulants Misc
    Harm Reduction All Topics Gabapentinoids
    Tired of your habit? Struggling to cope?
    Want to regain control or get sober?
    Visit our Recovery Support Forums

Propoxyphene nasylate for opiate withdrawal

Status
Not open for further replies.
I find that trams allows you to taper easier because they're not enjoyable to me and there for I abuse them less.

yeah you have to be careful though not to get hooked on the trams because i have heard you get the normal w/d syndrome plus a SNRI like withdrawal/discontinuation syndrome. but short term i think it can be a useful tol like you said.
 
yeah you have to be careful though not to get hooked on the trams because i have heard you get the normal w/d syndrome plus a SNRI like withdrawal/discontinuation syndrome. but short term i think it can be a useful tol like you said.


What's weird is that I seemed to be getting a little euphoria this time.
 
The reason for the conflicting reports is the slippery nature of this drug, in that form.

Yep it was actually formulated so it could not be abused in that way.

This is not accurate. Propoxyphene Hydrochloride was being abused via IV. While Propoxyphene Hydrochloride is still available on the market in the US, Propoxyphene Napsylate is much more common. While Propoxyphene Hydrochloride is soluble in water, Propoxyphene Napsylate is not. Therefore, you cannot crush and dissolve them in water to inject.

Also, a CWE would be pointless if you had a Propoxyphene HCL-APAP combo tablet because the doses for recreational Propoxyphene use before you get to toxic and unpleasant side effects would require you to eat less tablets than contain the APAP maximum dose.

The problem is you are basically prolonging w/d. once it wheres off you are probably going to be back where you started. Did you say you had a script of TRams? you could goto that next and take it for a few days.

While he may slightly prolong the overall withdrawal syndrome, it has been proven that using Propoxyphene in a detox regimine lowers the severity of acute withdrawal symptoms. Up until the 1970s it was very common for an opioid addict to be presribed Darvon instead of Methadone- even today many doctors (GPs) will prescribe Darvon along with Clonidine and a Benzodiazepine for an opioid addict in withdrawal.


The benefit for using Propoxyphene to aid in withdrawal is the long half life of its primary metabolite, Norpropoxyphene, which is 30-36 hours (Propoxyphene's half life is 6-12 hours). Twice daily dosing with reducing dosages on a taper schedule will ease you into withdrawal, with less severe symptoms. In this manner it has a similar benefit to Methadone and Buprenorphine for detox; the long half life means it takes an extra long time for your body to show symptoms of dose reductions. This gradual decline in blood serum levels of opioids and metabolites makes the symptoms less severe and the experience easier to handle.

I posted a link elsewhere on BL about a Dr. who used a typical Benzo/Clonidine detox with Darvon with great success. Propoxyphene allowed a lower dosage of both Clonidine and the Benzodiazepine used with better patient response.

Good luck.
 
Well it seems like i was right in worrying. Last night turned out to be a horrible delirious experience. I got two panic attacks in a row which has never happened to me ever, usually i will get one once every month or so. I felt like I had pushed my body to its limit with this drug. The metabolite does seem to take forever to leave your system which is why i was so worried in taking the drug three days in a row. i would have been better off just going through the opiate withdrawal cuz i felt better when the darvon wore off. i guess i just took to much throughout the three days (12 pills in total)
 
More likely you just had panic attacks. That's not what happens when you take too much.


no no. Ive had panic attacks since i can remember. Ever since i started doing drugs they have become worse and more frequent. Occasionally when i take any opiate i will get a panic attack during the high but the opiate softens the panic attack. This happens very rarely usually i get panic attacks when sober or in stressful situations. Yesterdays panic attacks were caused by the propoxyphene without a doubt. I have never had two in a row. whenever i get one and it ends im so relieved cause i know i wont get another one for at least a month but yesterday was just horrible. I knew that the darvon was building up in my system and yesterday was the tipping point.
 
no no. Ive had panic attacks since i can remember. Ever since i started doing drugs they have become worse and more frequent. Occasionally when i take any opiate i will get a panic attack during the high but the opiate softens the panic attack. This happens very rarely usually i get panic attacks when sober or in stressful situations. Yesterdays panic attacks were caused by the propoxyphene without a doubt. I have never had two in a row. whenever i get one and it ends im so relieved cause i know i wont get another one for at least a month but yesterday was just horrible. I knew that the darvon was building up in my system and yesterday was the tipping point.

Sorry for the bad trip man. Im glad you're cool now. I am sure the panic was brought on by the Darvocet and what ever dysphoria you felt as well. I'm just saying I doubt you were in any physical danger as far as overdosing. Trust me I KNOW how narly things can feel when you think you have taken too much of a drug and it doesn't feel good, panic sets in. It happened to me last night with methadone. Not fun.
 
.


The benefit for using Propoxyphene to aid in withdrawal is the long half life of its primary metabolite, Norpropoxyphene, which is 30-36 hours (Propoxyphene's half life is 6-12 hours). Twice daily dosing with reducing dosages on a taper schedule will ease you into withdrawal, with less severe symptoms. In this manner it has a similar benefit to Methadone and Buprenorphine for detox; the long half life means it takes an extra long time for your body to show symptoms of dose reductions. This gradual decline in blood serum levels of opioids and metabolites makes the symptoms less severe and the experience easier to handle.

Good luck.


This was very informative to me thanks.
 
This was very informative to me thanks.

Norpropoxyphene has really no analgesic effect and im guessing almost no opioid effects either. Norpropoxyphene has a greater local anesthetic effect then propoxyphene and is much like lidocaine in this regard. This is why when you take propoxyphene over a extended period of time it can mess with your heart. I think it can cause QT prolongation.

So no propoxyphene is pretty much good for nothing including withdrawals. Hell as much as i don't like tramadol i like it 1000 times better then shitty old darvon. If your in withdrawals take some lopermide if you can't get anything else such as codeine or whatever. Lopermide would work much better i think then propoxyphene.
 
Norpropoxyphene has really no analgesic effect and im guessing almost no opioid effects either. Norpropoxyphene has a greater local anesthetic effect then propoxyphene and is much like lidocaine in this regard. This is why when you take propoxyphene over a extended period of time it can mess with your heart. I think it can cause QT prolongation.

So no propoxyphene is pretty much good for nothing including withdrawals. Hell as much as i don't like tramadol i like it 1000 times better then shitty old darvon. If your in withdrawals take some lopermide if you can't get anything else such as codeine or whatever. Lopermide would work much better i think then propoxyphene.


I also have about 90 trams. I have about 4 days before I can fill my hydocodone script. Just hoping it might help a little.
 
Sorry for the bump, but I plan on detoxing/going through WD's in a few days. All I have is seven 100/626 propoxyphene tabs. Ideally I'd have a few valiums(for me, at least, V makes even the worst WD symptoms all but nil), but darvocet will have to do. "gulp"

Regarding panic attacks, I experienced the same thing one evening six or seven hours after taking 400mg of darvocet. I never have "natural" panic attacks, as the previous one's were all triggered by smoking marijuana...and I'm assuming darvocet contributed to one as well.

I plan on taking one 100mg pill every 12 hours for 3 days...I'll let y'all know if it helps/etc

Oh yeah, I've been on a 100 day or so(5-10 bags a day---snort, no IV) heroin/dormin binge.
 
Last edited:
^I'm sure it'll take a bit of the edge off but I wouldn't expect too much from 200mg propoxyphene a day for a gram (presumably?) a day insufflated H habit.

If I were in your shoes I'd certainly stock up on other pharmaceuticals (OTC and/or Rx) to ease the withdrawal. A gram a day is not going to be pleasant.
 
^I'm sure it'll take a bit of the edge off but I wouldn't expect too much from 200mg propoxyphene a day for a gram (presumably?) a day insufflated H habit.

If I were in your shoes I'd certainly stock up on other pharmaceuticals (OTC and/or Rx) to ease the withdrawal. A gram a day is not going to be pleasant.

I agree... You should most seriously see a Doc if you had that much of a drug problem.
 
darvocet seemed to help me a lot coming off of oxy, although i was at b/t 1.5-2 80mgs a day, insufflated, and your habit is higher (i was doing at least that amount every day for 2 years though, so it wasn't like some 3 week binge). nevertheless, i think the propoxyphene, some loperamide, and any benzos u can get your hands on will really make it better. at least i felt like they did in my case.
 
Last edited:
Propoxyphene Woes

First of all a little technical correction: The word "Nasylate" is incorrect. The correct word is "Napsylate" and simply means that this form of Darvon is "salt based".

I was first written Propoxyphene Hcl 65 Mg in 1980. This after my family Dr. and I researched a few different medications that I could take therapeutically to manage ongoing systemic pain. I learned that medications with additives, or compounds, would not work for me. Any kind of NSAID dealt me fits and even OTC Acetaminophen, Aspirin or ASA caused me to have "flushed" feelings that were very uncomfortable. As it turned out 31 years ago "Propoxyphene Hcl 65 Mg" was my "magic pill".:) Absolutely no side effects and that for which the medication was indicated far exceeded my expectations without the least degree of a "high" or "euphoric" feeling, even when my dosage was increased in the mid 1990's from four capsules per day to six. Since starting the Propoxyphene I have enjoyed a career in law enforcement, been a husband and a father and obtained a degree in business. So "normal" was it for me to take the Propoxyphene almost every day of my life since 1980 that I would sometimes use up an entire months prescription and be surprised when it was due for refill - which was always a monthly thing. I never exceeded the prescribed dosage and often refused other medications post-surgery because I simply didn't need them in addition to the Propoxyphene and never really considered that a day would come when Propoxyphene would simply be taken off the market. For me, for my body chemistry, this was the most innocuous medication I had ever seen. I abruptly stopped taking it under my VA Dr's care the last week of November, 2010.:X It never once dawned on me that to stop taking Propoxyphene would mean an eventual and actual "withdrawal" process just about like any other opiate. To make a very long story short and to the point, my VA Dr. prescribed for me Oxycodone to replace the Propoxyphene and that was a mistake. I simply don't have any tolerance for Oxycodone nor Hydrocodone the Rx next in line when It was obvious I was on the cusp of a life altering event. Well into the 3rd day after completely stopping the Propoxyphene and now fighting as I have never in my life known was possible with the Oxycodone and Hydrocodone I began experiencing "withdrawal" (in emphasis here because I still cannot believe I'm actually saying that word and applying it's meaning to me).:X This is NOT a poor, poor pitiful me thing simply because I had to make changes in my life - this is a retired law enforcement Deputy Sheriff and former Special Forces Soldier in the US Army during the Vietnam Era. Until the moment I am writing these words a little over 3 weeks after total cessation of Propoxyphene I am still in shock. I endured withdrawal symptoms including severe restless leg syndrome, clinical anxiety, depression, panic attacks, 3 and 4 day and night insomnia, headaches, very serious face-down in the carpet weeping, and much more until:;) Now if you are or have been addicted to the opiate Propoxyphene or any drug in the "Darvon" family or an opiate do I have wonderful and amazing news for you. NOW you will be glad you kept on reading. So severe were my withdrawal symptoms that I sat on my sofa looking at my phone and maybe seconds away from calling an ambulance. In utter desperation I began punching up items on Google and any other search engine I could load. My question to the main search engine, "Is there any way I can stop the withdrawal symptoms from 31 years of taking Propoxyphene?" A URL came up that pulled my teary eyes to it like a magnet - "SUBOXONE" as a humane method of enduring withdrawal symptoms of the opiate found in Darvon related medications". Here is the URL I pulled up for Suboxone: http://www.drugs.com/suboxone.html Literally within a few hours I was sitting in front of a specialist at the VA Hospital - the only one at the entire VA campus who was licensed and trained to discuss and administer as a prescription Suboxone. (That is a condition of being able to discuss with patients and administer Suboxone. The prescriber must be specifically qualified). Within another couple of hours I was back home sitting on the same sofa staring at the clock with a prescription for 12 2 Mg tablets of Suboxone. It was approaching 5:30 pm. The instructions were to go home, take one Suboxone pill sublingually (under the tongue like Nitro Glycerin) with the words ringing loudly in my ear that were the answer to the most important question I asked the specialist - "When I take the first dose of Suboxone, what will happen to me?" His answer, very matter-of-factually given yet with a broad grin, "ABSOLUTELY NOTHING"! 10 minutes after I took the first 2Mg tablet of Suboxone and well into my "next" onset of withdrawal symptoms the most amazing and absolutely most welcome thing imaginable happened to me..... "ABSOLUTELY NOTHING"! Gone was the totally debilitating bout with Restless Leg Syndrome, gone was the headache, gone was the INDUSTRIAL STRENGTH pins and needles thing in my chest and arms - and as soon as I could ascertain for a certainty that what was happening was in fact this HUMANE relief from hell I never knew existed I once again found myself in the kneeling position on the floor totally soaking my living room carpet with tears. Tears that were in no way drug or withdrawal from drugs induced but tears of profound gratitude. I truly never even knew I was a prisoner to Propoxyphene and now to all intents and purposes I could force myself to stop just for a moment and say to myself - "You are FREE of drugs..." So dramatic was my experience and so deeply I want to reach out and help anyone I can find to experience the joy I came to know I have reduced the entire experience to an axiom... "There are times which mark our lives... moments when you realize nothing will ever be the same... and time is divided into two parts... before this and after this..."
 
Last edited:
Status
Not open for further replies.
Top