Promethazine/Codeine | Hydrocodone

[Alx4m916]

So I'm on about 25mg of hydrocodone atm and I'm wondering what's the difference between the two? Is promethazine/codeine anything like hydrocodone?

 

[MikeRWK]

Hydrocodone is stronger, youd be better of combining the prometh with hydrocodone.Someone can correct me if im wrong

 

[pally pete]

I guess the Promethazine would potentiate the Hydrocodone.

 

[MikeRWK]

I guess the Promethazine would potentiate the Hydrocodone.

As will dph but dph will also make you drowzy

 

[pally pete]

As will dph but dph will also make you drowzy

So will Promethazine, thats what i actually meant by 'potentiate' (Increase the Nod factor) that is if that what you are looking for?

As a another + either of these 1st generation Anti-Histamines also will help with any itchiness or nausea you may experience.

Have fun and stay safe!

 

[Pjkt2501]

Actually, "potentiate" means "to increase the effects of" - and falling asleep isn't an opiate's #1 goal. Thus, DPH isn't actually potentiating the opiate, just potentiating the nod.

Promethazine does the same. They both however have anticholinergic effects and cause delirium at higher-than-recommended doses.

Codeine is much weaker than Hydrocodone. The syrup probably has an unfavorable ratio of codeine to promethazine for it to be recreational in itself, but adding it to the base hydrocodone with intensify effects of all compounds (aside from the promethazine-induced delirium if you reach that point).

 

[Mr Blonde]

Codeine is weaker (no personal experience 'cause we don't get hydrocodone here) but I still like it. Can cause uncomfortable histamine release in larger doses. Mixing with promethazine is a good idea, but if it's in the syrup as was pointed out by Pjkt2501 it's not the best ratio and will limit the amount of codeine you can comfortably consume.

 

[GABAking]

1) Go to nearest gas station
2) Get a styrofoam cup and fill it with sprite
3) Pour that promethazine-codeine syrup in with the sprite (I think I did like 4 or 5 oz??)
4) Drink that over a couple hours.

even though codeine is weaker than hydrocodone, "purple drank" fucks me up wayy more

 

[NeighborhoodThreat]

^The reason for that is the high amount of promethazine in most codeine/promethazine syrup preparations.

 

[RedBaron]

1) Go to nearest gas station
2) Get a styrofoam cup and fill it with sprite
3) Pour that promethazine-codeine syrup in with the sprite (I think I did like 4 or 5 oz??)
4) Drink that over a couple hours.

Make sure there's crushed ice in dat there styrofoam cup! But as everyone mentioned here, they syrup mainly effects you with prometh, and codeine is in there for a light blanket.

I know I came across some codeine in solution and I was already at the ceiling dose 8). I wanted to turn it into something yummier, but no luck with what was needed.

Also to those saying to use antihistamines, I've heard that they inhibit CYP450 enzymes that turn codeine to morphine. So you will actually reduce your dose potentiation, and become mostly drowsy... The only things I use for codeine are GFJ 1hr before, tonic water 45 mins before, immodium+dxm 30mins before, 1500mg calcium carbonate(tums) 10mins before. That's the best combo I've found. I can still get pin-point pupils off a ceiling dose!
DXM supposedly dose similar CYP inhibition to antihistamines, but not to a large degree (i.e. the benefits of tolerance stop/reduction overcome the very slight decrease in effect. The reduction in tolerance probably increases the overall effect.)

 

[Pjkt2501]

The conversion to morphine accounts for ~10% of codeine's actual analgesic effects, so while yes this does occur, it doesn't hinder the effects of codeine in any significant way.

I can find the source if needed, but I'm referencing what was mentioned by another (very knowledgeable) moderator.

Also - ceiling dose in individuals varies by user. I know of two instances where it's been effectively nearly doubled per use (and done multiple times per day).