• N&PD Moderators: Skorpio | someguyontheinternet

Preperation of Dex to stop me abusing it

I have never had sodium valproate, it sounds awful due to the drowsiness, cognitive impairment and general 'zonkage.' That is why I cannot tolerate phenytoin--it knocks me the fuck out. I am currently on dexamphetamine SR, venlafaxine XR (Effexor XR) and Lamictal (at 300mg qD). I definately think that the combination of dexamphetamine and the right mood stabilizer (absolutely key, to prevent amphetamine-precipitated mania) is a great combo for bipolar disorder. Everyone has different responses to different mood stabilizers--for me, Lamictal has been the best.

It sounds to me, streetsurfer, like you are on the IR version of effexor, so you might have had a dose wear off during the day and never reached stabilized plasma levels. Try the Effexor XR or BID/TID dosing of itty-bitty portions of regular effexor. Also, maybe upping the Lamictal (slowly, only as fast as you can tolerate it and have no dermal side effects) would help. I know that Lamictal has been a godsend for me as a mood stabilizer, but unlike lithium and phenytoin, it does not stabilize my mood by just zonking me out--it actually has anti-depressive properties in addition to its anticonvulsant properties. I am also bipolar ('BP II,' mainly depression), but your pharmacogenic profile may vary.
 
I was screwing around with the valproate, anywhere from 500 - 1200 day. I was manic on Dex at the time


I am on the XR venlafaxine.
I am taking 75mg in the am, and a half dose at lunch and that seems to have fixed the problem.

Lamictal at 300mg qD? Once daily yeah? We don't tend to use that abreviation over here. It would be written 300mg nocte or mane.

So what do u arm for Rieman, do u aim to be bubbley and happy or what, how do u decide how well is well and how long since ur last med change. Also do u think tolerence will set in for effexor? Can u cycle antidepressants for a good effect?
I only have regular dex's. It takes 2 to get me going propperly, how should I dose for the rest of the day?
Thanks
 
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Ok, Dex's are here today I am going to make up a capsule as follows:

7.5mg Dex
300mg ibuprofen
25mg lamictal



I know that for me picacetam noticiably potentiates stimulants. Maybe picacetam might increase the pyscho stimulant effects of the selegiline and be enough?

I assume u mean pirecetam? yeah I want to give that another go, It would be great if I could ditch dex altogether and substitute with aniracetam and pirecetam

Agree with the above, but like I said perhaps it is best to focus on the issue that causing the most problems, and I imagine that the depression would be it. Once that is pretty sorted then you could look at the ADD.

Depression is pretty under control with sideffexor, except for the god damned dyskenesias
 
I'm pretty sure whoever that is means 2-(2-oxopyrrolidin-1-yl)acetamide. I've found that piracetam and aniracetam don't do anything for me except make me feel like I've had a mild nicotine overdose (cold sweats, hot flashes, nausea, dizziness, fatigue, etc). Apparently these "nootropics" work for some people though.
 
streetsurfer said:
I was screwing around with the valproate, anywhere from 500 - 1200 day. I was manic on Dex at the time

I found a good combo:

I take 10mg of Dex after breaky, then i take 10 mg of Dex after lunch, and with that 40mg of Propranolol which is a great combo, and would suit you alot i think.

The Propranolol (beta blocker that enters the brain) gets me high, but i loose the Dex scatered ness, and makes you feel much calmer and focused.

Then after dinner 500mg of Sodium Val to get a nice sleep, and if you are still wound up from the dex, another 40mg of Propranolol, and you will sleep like a baby and feel super calm and relaxed but still focused.

I find 40mg of Propranolol gets me a bit high, but 80mg actually makes me a bit flat. In the day i want to be a bit high, but late at night, especially trying to sleep i want to be a bit flat and have nice sleep.

Propranolol is Very easy to get off the internet, and my GP gave it to me no problem- just say you want a slow heart while you sleep.

Hint: alpha1b receptors increase dopamine, beta receptors lower dopamine.
 
Riemann Zeta said:
I have never had sodium valproate, it sounds awful due to the drowsiness, cognitive impairment and general 'zonkage.'

i have read that a few times but it is simply not true.

I have been on 500mg after dinner most nights (I skip when i want to drink alcohol because i get a bad reaction) and it just makes me sleep better - the next day i am totally fine and not groggy at all.

My best 2 friends (one is Bi-polar type I and the other is ADHD - both are visual artists) are on 2000mg a day and are not 'zombies' at all. They are still 'full of beans' , but they just act alot more normal.

Try it before you knock it !

Hint : It goes REALLY well with Dex amphetamine.
 
I had an idea of a way you could do it, what if you disolved a dose in a certain ammount of water or other liquid. That way I would be limited by how much I can drink. Could you store it (say in the fridge) for a month or two without it breaking down? Could you mix it with cola? pepsi max? cordial? Thanx
 
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