Preparing a multi use iv/im/subq vial

[crazycatman]

No I am not intending to do that, just courious if I missed anything important.
You would need a sterile sealed vial, syringes, needles, micron filter , bacteriostatic water, substance to be dissolved (pure powder not pills), glass beaker.

First sterilize the beaker in boiling water (leave for 30 min or more).
Then add the powder and some bacteriostatic water (draw it with a sterile syringe obviousely).
Draw the solution into a syringe, attach a filter and to it a needle.
Inject that to your sterile vial. Maybe add some more preservatives.

Is this about it or did I miss something? How long would the shelf life be? Would it need to be refrigirated?

 

[Swimmingdancer]

It depends on the substance. If it is in fact truly pure and it's not just whoever sold it claimed it was pure - in the latter case I would filter the solution. Different substances have different shelf lives in water. Some things degrade in water very fast and aren't suitable for storing this way, whereas some are fine for a very long time - most are in between, but you'd have to be more specific in order for me to give better info.

 

[crazycatman]

It was just a general question no specific substance in mind, but lets say the substance was pharm grade and stable (like one of the 2c-x for example).

I know things like HGH would have to be kept cooled and thinks like steroids can take a lot of abuse.

 

[Swimmingdancer]

If it was definitely pharmaceutical IV grade and/or you're filtering it properly and it was definitely stable in water, then everything sounds good except that boiling the beaker wouldn't necessarily truly sterilize it. Dry heat is better for sterilization. Like you could put it in the oven.

 

[crazycatman]

Thanks for the tip. So that + filtering it should make it sterile? How about a pressure cooker instead of an oven?

(it's just a really interesting subject thinking about those things)

 

[Swimmingdancer]

The problem with a pressure cooker is that you will need to add a bit of water in the bottom of the pot, and so the beaker will come out moist, so when sterilizing with a pressure cooker it is normally recommended to put the item in the oven to quickly dry it afterwards anyway. But I'm sure you can look up instructions for sterilization using a pressure cooker.

Whether filtering will make it sterile depends on the filter and pore size used and whether there is any incidental contamination after the fact. But honestly, to make something sterile means to pretty much guarantee that it is totally free of all live bacteria and other microorganisms (and their spores). In reality that's impossible to fully do properly at home without specialized equipment and handling. For general purposes getting as close to that as possible should be good enough in my opinion. And the bacteriostatic water will stop any bacteria from growing if there were any that made it in, so it would be unlikely that there would be high enough numbers that your body couldn't fight them off. It is certainly way better than how many people prep drugs for injection!

 

[crazycatman]

The filter would be 0.2um (that's the smallest right). I know it wouldn't filter viruses and maybe some bacterial spores is there anything else? Could you expose the finished product to UVC radiation assuming that the drug in question is stable enough? Or some sort of radiation source (not that that is freely available)? And of course you can buy an actual autoclave on ebay if you're lucky...

>And the bacteriostatic water will stop any bacteria from growing if there were any that made it in, so it would be unlikely that there would be high enough numbers that your body couldn't fight them off.
Yes that's what I read on some steroid homebrew sites - a tiny amount of bacteria is acceptable for people with normal immune systems and most infections come from stupid injection practices. Of course steroids are in oil which usually isn't as friendly to bacteria.

Anyway I feel this is an interesting discussion HR wise, if anyone has some more to add, please do, it's an interesting subject for me.

The only problem I see is if the powder is contaminated with heavy metals and such.. or prions (do filters remove them? don't think so).

And now I actually make to want this, just to prove I can make it safe.

Any takers on using UVC and or Xrays to sterilize it even more? Or would Xrays be to strong and destroy the compound?