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Pregabalin / Lyrica

chinup said:
i have the opportunity to get some pregabs so i might as well, might help with the brutal insomnia that's been making me suicidal recently. i haven't had them since i was using, and only had diverted scripts so they were def legit and dosed as stated.

my mate is getting these off the darkweb, the options are Sandoz, Signature, or UK Pharma (dunno if that's a brand or just meaning some UK company...). there is a significant price difference. anyone got any experience with pregabs from any of these? she is usually quite good in choosing vendors etc for making sure things are what they say they are but i know some brands are hit and miss.
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Signiture 300 i had few thousand they legit from India
 
I've done this a few times now, been through benzo WD, so not sure about tolerance.

900 wiped me out and turned me into a dribbling wreck.

450 has me buzzing, but just not enough. If I snort another 150mg will it hit me quickly?

I'll do 600mg next time, might be the sweet spot.
 
I've read through this whole threat but still not really got the answer I was looking for.

First time I tried it 400mg had me feeling like I was 21 again, the muscle relaxation, felt happy go lucky and like my mobility/agility was so good.

I've tried 300mg a couple of times now but didn't get the same feeling. And I only have 300mg capsules, which I suspect 600mg would have be too noticeably fucked up.
 
^rip a small square of paper towel. pull apart the 2ply so that you have a thin piece of paper towel. open the second capsule. pour out one third. ball it up and swallow.
 
Nipper76 said:
I've done this a few times now, been through benzo WD, so not sure about tolerance.

900 wiped me out and turned me into a dribbling wreck.

450 has me buzzing, but just not enough. If I snort another 150mg will it hit me quickly?

I'll do 600mg next time, might be the sweet spot.
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I just recently discovered Pregblin/Lyrica and fell in love with it's effects instantly. It's like valium without sending me mad and looking for other drugs after.

I find 300mg doesn't quite get me where i want to be.

450mg first thing in the morning parachuted, is like feels good, and if I don't eat for a while i do have notable effects.

600mg first thing (like I had this morning) is enough to give you all the pain relief and energy of 1000 men.

900mg, i think would be too much first thing in the morning. However I went to make up 2 x 450mg doses inside rizlas for tonight and tomorrow morning, trying to ration the rest of my stash. And guess what? I've taken both them parachutes down with hot coffee.

I have noticed it's like the redose is never as strong as the initial dose, and you are definitely better having it before food.
 
How many mgs should I first timer need to get good stoney effects? Like i tried snorting 75mg last night and got a minor effect, mostly just made me lethargic/lazier. I know i should have took them orally (partachuted) because the first pass metabolism is needed for the recreational quality; but i thought 75mg would be nothing oral. Im looking for a decent stone, couch lock high, which sounds like what a sufficient dose should do. 150-300mg??

Sorry for bumping old thread but it seems like a nice one to revive.... instead of making another whole Lyrica/pregablin thread.
 
Yeah snorting pregabs is no good at all.

From my experience it's not a couch lock substance. It's energising. 75 mg boosted my mood. 150 I mixed with other things so will comment on that later.. more than 300 felt like a bad trip, sans psychedelia. (I know this is just my brain chemistry, and it's unlikely that anyone else will react in the exact same way that I do)

But I've never seen a substance that has so much YMMV as pregabs. Everyone that's posted about it on here reacts totally differently to different doses.

This is a terrible HR thing to say, and could be dangerous or fatal if you don't work up carefully and gradually with each substance, and learn how you combine them, erring on the side of caution always. And it could still go wrong if you're susceptible..

Pregabs can enhance the effects of other downers. Rather than doing much of that in it's own right.

As I said it's very dangerous territory, and probably totally irresponsible of me to make this post.

In my defense, I have warned of the dangers. Please heed them very seriously.
 
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thegardensallnighterz said:
How many mgs should I first timer need to get good stoney effects? Like i tried snorting 75mg last night and got a minor effect, mostly just made me lethargic/lazier. I know i should have took them orally (partachuted) because the first pass metabolism is needed for the recreational quality; but i thought 75mg would be nothing oral. Im looking for a decent stone, couch lock high, which sounds like what a sufficient dose should do. 150-300mg??

Sorry for bumping old thread but it seems like a nice one to revive.... instead of making another whole Lyrica/pregablin thread.
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Just take 150mg and increase if you're comfortable with that. Or be daring and do 300mg. Neither should be a problem.
 
Ok thankyou guys
I took 100mg. I just dumped the powder in a cup of tea and I have another 50 in an hour kinda like how ppl stage the gabapentin capsules. Im also on methadone and taking promethazine and hydroxzine, with a trazidone.
 
Yeah layering smaller doses works very well ime. I bomb the doses in a rizla as the powder doesnt taste good.

I hope you were OK with all of that combo, but seeing as you're already on Methadone, which I didn't realise, then you'll know the score re combining downers.

You may have had trouble waking up and getting out of bed this morning.

Pregabs and /or Soma do that to me.
 
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Yeah, there is some confusion about that, so I just expressed it simplified.

Basically oral dose has best bioavailability and all that, even if one could get stuff work by other ROAs too, I don't suggest that. Also because gabapentinoids are often cut with talc and taking a habit of snorting talc-gabapentinoid compound might be unhealthy for your lungs eventually.
 
No point snorting gabapentin or pregabalin imo. Positively pointless.

Works well orally or rectally ime.

I took 900mg of pregabalin first time I tried it. This was not wise. I literally struggled to stand without repeatedly falling directly upon my arse. For hours. Walking was a sure fire no-go.

As for combining with GBL/GHB… holy fuck is that insanely euphoric. Like beyond belief euphoric. Was quite literally rolling around onna concrete floor borderline orgasming for a couple hours. Truly ridiculous shenanigans.

/hr
 
Bleaney said:
Yeah layering smaller doses works very well ime. I bomb the doses in a rizla as the powder doesnt taste good.
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I just took 200mg (dissolved capsules in coffee) and staggered another 75mg about 2-3 hours after the 200mg. It took a while to start feeling it, but it crept up on me after 3-4 hours.

Im starting to feel kinda dizzy or a little tipsy and my head feels really light. Im gonna dose another 75mg in about 2-3 hours, 200+75+75 totaling 350mg. Seems 200mg is where the buzz starts.

Staggering kinda working:
dosing another 50-75mg an hour or 2 after the first dose. It kinda boosts the good effects very well. That's how I got gabapentin to give me such a strong weed like effect. I like these gabanergics they are fickle.. but when they work they have some fuzzy wuzzy buzz and have good legs
 
Just take the capsules on an empty stomach. It is already absorbed rapidly and nearly completely unlike gabapentin. Like 90% bioavailable. Taking the capsules apart and parachuting is not going to change that and bits of active ingredient may be lost in the process. Here's a copy pasta from the pubmed pregabalin stats page:

Pharmacokinetics

Absorption: Pregabalin is absorbed in the small intestine and proximal colon in a linear and dose-proportional fashion. However, differences have been noted between pregabalin controlled-release and immediate-release formulations. Pregabalin controlled release (CR) achieves peak plasma concentrations within 8.0 hours (range: 5.0–12.0), contrasting with the more rapid attainment of peak concentration seen with immediate-release pregabalin, typically occurring at 0.7 hours (range: 0.7–1.5).

Distribution: Pregabalin's apparent volume of distribution is approximately 0.5 L/kg. Pregabalin does not bind to plasma proteins.[20] Pregabalin readily crosses the blood-brain barrier.

Metabolism: Pregabalin does not induce or inhibit liver enzymes such as the cytochrome P450 system.[21]

Excretion: Pregabalin is primarily eliminated from the systemic circulation via renal excretion as an unchanged drug. In normal renal function, the mean elimination half-life of pregabalin is 6.3 hours. Pregabalin elimination is closely linked to creatinine clearance and is approximately proportional to creatinine clearance.
 
Shambles said:
I took 900mg of pregabalin first time I tried it. This was not wise. I literally struggled to stand without repeatedly falling directly upon my arse. For hours. Walking was a sure fire no-go.
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Key consideration here. Pregabalin lasts fucking forever. I'll take 300-450mg around 7pm and still be bumping into things and sliding off walls late the next morning. Not one to take when you have work the next day.
 
Since lyrica stays(lasts) so long you think adding like 75-100mg, to like a starting dose of 250-300mg, after like 3-4 hours will increase the effects of the initial 250mg?
 
Shinji Ikari said:
Key consideration here. Pregabalin lasts fucking forever. I'll take 300-450mg around 7pm and still be bumping into things and sliding off walls late the next morning. Not one to take when you have work the next day.
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I agree that it does make getting out of bed more difficult on the following morning.

But I can only feel the 'psychotropic effects' for around 4-6 hours, hence the re-dosing or layering at those kind of intervals, where it definitely stacks up.

It's kind of subtle at the 100mg at a time doses I take, but I notice a further reduction in anxiety and inhibitions when out and about.

I tend to use it as background substance to combine with other things that work well together; like kratom, benzos, and weed.
 
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