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  • BDD Moderators: Keif’ Richards

Pregabalin 300mg Advice needed

yenyama

yenyama

Greenlighter
Joined
May 15, 2026
Messages
2
I’ve been wanting to do Pregab but my friend’s friend had a seizure from it and I’m Highkey scared to do it. I opened up the capsule of pregab 300mg like half and half most likely not exactly the amount I thinked it was. I did that twice. And I felt nothing. So I wanna do 300mg now. But I’m still scared. I just need a bit of reassurance. I’m 172cm And 68kgs
 
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You should be fine for 300 - 600mg at once. Going over a gram and it starts to get a bit risky IMHO.

As Shinji says it takes a while to kick in. Caught me out the first time. Oops.
 
Like mentioned ⬆️ & ⬆️⬆️ takes a lot of time to kick in the first dose. So 150 mg for a novel user will hit like a bomb, going from my first time experience 20 years orso ago.

Dosing more seems overkill, but YMMV. Wont kill ya but expect next day lingering !
 
I would add that you've done the scary bit already, you've had some as an allergy test....

take it slow if you're worried and gradually increase the dose, but 300mg in 1 go shouldn't be an issue

also in terms of time to kick in 90-120 mins oral isn't unusual, it's much faster insufflated though
 
placebonaut said:
also in terms of time to kick in 90-120 mins oral isn't unusual, it's much faster insufflated though
Click to expand...
Does that work ? i did try several times but never felt it happened. Kick in and then someone brought one Zwitterions properties explaining that it couldnt be insufflated.

Even trying to understand a term like that going above my head i accepted as the reason why it didn t work. No idea if it is though, but when done that way the drip is horrible ime. Doesnt lend itself for that ROA. It reaches the stomach eventually so ..

https://pmc.ncbi.nlm.nih.gov/articles/PMC6608624/
 
I find 450mg is my sweet spot for a recreational dose, it takes about 45 min to start coming up and as has been stated about 2 hours to really kick in.
 
emkee_reinvented said:
Does that work ? i did try several times but never felt it happened. Kick in and then someone brought one Zwitterions properties explaining that it couldnt be insufflated.

Even trying to understand a term like that going above my head i accepted as the reason why it didn t work. No idea if it is though, but when done that way the drip is horrible ime. Doesnt lend itself for that ROA. It reaches the stomach eventually so ..

https://pmc.ncbi.nlm.nih.gov/articles/PMC6608624/
Click to expand...
yep snorting works, faster onset, shorter duration, harder hitting, makes it a bit more edgy for me.

you can get 300mg up your nose without any drip, use both nostrils. If you're getting drip you're being too aggressive with it, I like to pour it into my nose from the capsule with my head back and give it a little sniff.

just had a look at the paper and not sure I'm seeing what's relevant around ROA here, it's more about stability and ability to press into pills I think, the H2O makes the compounds more flexible and less likely to shatter.

not sure about Zwitterions properties either, quick search and 1 of the factors is that they tend to have high water solubility, I thought it was pretty common knowledge that you can snort pregab?
 
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quick and lazy search, there aren't that many papers about it but there are some out there


Intranasal Pregabalin Administration: A Review of the Literature and the Worldwide Spontaneous Reporting System of Adverse Drug Reactions - PMC

Background: It is repeatedly reported that pregabalin (PRG) and gabapentin feature a potential for abuse/misuse, predominantly in patients with former or active substance use disorder. The most common route of use is oral, though reports of ...
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
 
300mg pregabalin is a pretty subtatial dose for a first time, but you are not going to suffer any damage from it, worst case cenario is you get dizzy and nauseous and have to lay down to stop it.

If you are not planing on get right out intoxicated, but just want the euphoric soothing, mood lifting kind of effect, 50mg ought to be plenty for a first time.

Then again everyone's brain chemistry is a bit different.

As with many unfamiliar drugs also it is more likely a case of you not knowing how it works, how to feel it and what to pay attention to, than it actually not working as it is supposed to.

Also personally I prefer to eat it.

To me it actually works better that way.
 
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Dont snort this, just eat it and wait. 150mg for first time made me drunk-like, 300 would do something definitely. And yes it can cause seizures but if not combined and not using more than 600mg it's very rare.
 
In the past I've taken 300mg! But if I remember rightly they were 50mg capsules so I'd take 6 at once then afew hrs later I'd repeat to make it 600mg felt wobbly as if I'd drank 6 pints of lager lol
 
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