i think this is true, its worked on my doses and ive been from 70, to 85, to 100 currently. and sorry about babbling or anything, 2nd day missing my methadone dose.....uggghhhghhh
tagamet, WHITE grape fruit juice (real).dxm, ibuprofen, benedryl, alcohol, #benzos# BUT (benzos are a HUGE NONO when on methadone it can be very very dangerous, like straight up DEADLY. drinking alcohol and any other sedative, or over drinking/getting drunnnnnnnnkk with just your regular methadone dose can be just as bad) ive taken benzos on my dose but always has been at least 1.5 days after my last dose. ive banged em too (yeah dumb, but when you are lookin for instant relief you get a lil crazy and stupi.
the tagamet/cimetidine makes your body metabolize the methadone slower, and the white grapefruit juice does as well. it inhibits certain chemicals that break down the drug resulting in longer activity and stronger feel, it will affect a whole range of drugs, most recreational ones in fact it seems. the data is easily found and very valuable economically speaking

just get comfortable with what you are doing and take the time to learn the right dosing and timing and drugs to use with what drugs. aside from not doing more harm to your body, youll get the most out of yur stash/dose. search for "cytochrome P450 inhibitors" on google and wiki and this site is great-
http://www.opioids.com/opiates/index.html and this one too
http://opioids.com/index.html
i havent been on here in forever, so im sorry if direct linking is bad or what, just let me know.