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potentiating methylone (5htp? oxiracetam?)

csrpj

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Joined
Nov 3, 2009
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161
i'm on methylone now, i'm underwhelmed (170 mg, i'm 140 lbs). i did it alone in hopes of a "therapeutic experience" - to think about my inner shit and stuff....

i've done it before with much greater feelings, now it's not especially great, and i'm thinking if i could take anything i have to make it stronger.

could i take 5htp now? it's been great for comedowns, but during the experience - could it potentiate it?

i've already taken piracetam. i have oxiracetam though - should i take this? (dam i wish i have aniracetam in stock - that's my favorite ;)

as far as other stuff, i only have vitamins/minerals/other supps, SAMe, selegeline, and aMT. any of those may help?

thanks, hope to get some replies soon.
 
I would not take selegeline or aMT at this point. Vitamins and minerals always help, I don't know much good they'll do during the experience, however, they may help with the comedown.
 
yeah i figured to avoid both of those...

i guess i should just relax and accept things as they are, but lately i've been feeling so bad in my life, i was looking forward to a strong empathogenic solo experience.... anyway, any guess if 5htp, SAMe, or oxiracetam may aid the experience?
 
i'm on methylone now, i'm underwhelmed (170 mg, i'm 140 lbs). i did it alone in hopes of a "therapeutic experience" - to think about my inner shit and stuff....

i've done it before with much greater feelings, now it's not especially great, and i'm thinking if i could take anything i have to make it stronger.

could i take 5htp now? it's been great for comedowns, but during the experience - could it potentiate it?

5-HTP supplements do absolutely nothing. It's a placebo.

And all of the "scientific test" that show otherwise are all flawed. Because they take someone who has not taken any substance and suffers from depression. The test group takes the SSRI and the other group takes the 5-HTP... well of course you're not going to see any improvement, or even worsening of symptoms of the groups taking SSRI's. It takes at least 30 days for them to begin working properly. And generally they worse depression during the first 30 days.

The best thing you can do is simply take multi-vitamins. If you are taking tablets, dissolve them first.

Exercise and keep a healthy diet.

You will naturally improve as opposed to taking strange supplements that are hardly regulated at all.

There is a reason why they are not regulated by the FDA.

Only a tiny fraction of consumed 5-HTP is actually converted and makes it through the blood brain barrier.

In theory: Tryptophan --> 5-HTP --> Serotonin.

However, what is not taken into account how much of it is destroyed in the digestive system.

And it can be proven that virtually all of it is excreted because one only has to look at the metabolites that 5-HTP creates that would be excreted from the body. The amount of this metabolite is only even remotely higher than normal if the subject was to take GRAMS of 5-HTP.

It simply doesn't work. It's based on a theory (and in theory in theory it seems as if there is no doubt that it would work. However, it doesn't. And it was long debunked. But people just want to believe and listen to junk science because it makes them feel better, like God or saying you want to take America back.... from what? The majority of Americans who voted for the president (he won the popular vote AS WELL as the electoral vote) and the representatives in the House and Senate?

i've already taken piracetam. i have oxiracetam though - should i take this? (dam i wish i have aniracetam in stock - that's my favorite ;)

I don't know about oxi or ani, but Piracetam does actually work. Although I'm not sure what it does to re-up your supply of neurotransmitters.

as far as other stuff, i only have vitamins/minerals/other supps, SAMe, selegeline, and aMT. any of those may help?

Your honest to God best bet would be to eat healthy food that contains all of the vitamins and minerals you really require. Your body assorbs vitamins and minerals more efficiently that way. Many supplements are a joke. And if you want to take a multi-vitamin, do a test first. Drop whatever into a glass of vinegar, which closely mimics how a human stomach will break down a pill. If it's completely dissolved within 45 minutes, it will work. If not, like Centrum, you should crush it up first.
 
5htp does work but you needed to have taken it two days before the methylone. IME methylone is a bit shit.

best avoided
 
No experience with any of the things you've mentioned there, but there are a few things i have used successfully to potentiate methylone. Taking some quick acting antacids immediately beforehand will basify the stomach and reduce the amount destroyed before absorption takes place. Grapefruit juice contains some furocoumarins which inhibit CYP3A4 & CYP3A5, which are liver enzymes that are involved in the metabolism of a large number of drugs. Though I'm unaware of any hard data on if this has definite effects on M1 or MDMA. I've attempted this a couple times, and it did seem to increase the duration of the desirable effects, might have made the subjective effects a bit more intense, but that's hard to quantify. Definitely tread lightly if you decide to attempt that method. In the realm of other drugs, i've had good luck with dosing 2c-c and/or 2c-d about 1-2hrs beforehand. Dosing MDAI at the same time also works wonders :D. Remember though, YMMV and always slowly step up combinations over several experiences to make sure you don't have an idiosyncratic reaction.
 
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