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Potentiate Lunesta?

EliseBug

Greenlighter
Joined
Sep 21, 2017
Messages
18
I just got switched from ambien to lunesta and it?s not nearly as strong, I haven?t been able to find anything about grapefruit potentiating lunesta but I thought I saw it on here a long time ago. Does it?
 
Lunesta is metabolized via CYP450 3A4 and CYP450 2E1, so WGJ might help a little, Cimetitidine as well, but the gains from either are most likely going to be negligible. You're probably going to have a longer duration of action vs an improved sedative punch, but if it does somehow work miracles for you please report back.
 
Hmm, Interesting..Would you say it added to the sedative effect or duration? Any hangover effects?
 
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