Just a little pinprick
Bluelighter
- Joined
- Dec 8, 2019
- Messages
- 1,144
I can’t stand the next day yawning, fucking hate it.
Classic WD from opi syndrome. Just gotta wake and take a shot or two. Hair of the dawg, baby.I can’t stand the next day yawning,
Nitpicking but I'd say it's the D2 antagonismus (like your favourite antipsychotic does) which causes loss of interest in sex. SSRIs tend to mess with the ability in men but less so the interest. I'd love to separate the antipsychotic alkaloid from the opioid mitragynime but once I'm not a chemist and twice I read that it might be mitragynime itself having those side effects but it's possible that they confused the terms, wouldn't be the first time.providing a mild SSRI type effect, which wasn't something I signed up for. I noticed If I used fairly large doses of kratom then my interest in sex dropped significantly. This seems to be a common side effect and not one I can accept.
Nitpicking but I'd say it's the D2 antagonismus (like your favourite antipsychotic does) which causes loss of interest in sex. SSRIs tend to mess with the ability in men but less so the interest. I'd love to separate the antipsychotic alkaloid from the opioid mitragynime but once I'm not a chemist and twice I read that it might be mitragynime itself having those side effects but it's possible that they confused the terms, wouldn't be the first time.
But based on the withdrawal symptoms it's indeed likely that we have a SSRI here - the paper I read only described 5ht2a, D2 antagonism, mu partial agonism and adenosine antagonism (like caffeine). Then kanna (Sceletum tortiosum) would be a good aid for Kratom withdrawal, it was effective for venlafaxine which is one of the worst antidepressants in relation to abstinence effects. Or fluoxetine which after a while has a half life of more than a week and tapers itself.
One encounter with Codeine. Some Tramadol. And o-DesmethylTramadol. I honoustly didn't experience any of the described effect's on Kratom. Neither on my libido or as of coming of a SSRI which sounds like horror.Nitpicking but I'd say it's the D2 antagonismus (like your favourite antipsychotic does) which causes loss of interest in sex. SSRIs tend to mess with the ability in men but less so the interest. I'd love to separate the antipsychotic alkaloid from the opioid mitragynime but once I'm not a chemist and twice I read that it might be mitragynime itself having those side effects but it's possible that they confused the terms, wouldn't be the first time.
But based on the withdrawal symptoms it's indeed likely that we have a SSRI here - the paper I read only described 5ht2a, D2 antagonism, mu partial agonism and adenosine antagonism (like caffeine). Then kanna (Sceletum tortiosum) would be a good aid for Kratom withdrawal, it was effective for venlafaxine which is one of the worst antidepressants in relation to abstinence effects. Or fluoxetine which after a while has a half life of more than a week and tapers itself.