Post-study caffeine administration enhances memory consolidation in humans

slimvictor

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It is currently not known whether caffeine has an enhancing effect on long-term memory in humans. We used post-study caffeine administration to test its effect on memory consolidation using a behavioral discrimination task. Caffeine enhanced performance 24 h after administration according to an inverted U-shaped dose-response curve; this effect was specific to consolidation and not retrieval. We conclude that caffeine enhanced consolidation of long-term memories in humans.

http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.3623.html
 
How Caffeine Can Boost Your Memory

Caffeine is known to confer a number of brain-boosting benefits, but its influence on our ability to store and recall information has never been properly explored. A new study corrects this oversight, showing that caffeine can help us recall certain memories — and it's an effect that lasts for at least 24 hours.

Caffeine is considered a cognitive enhancer on account of its stimulant properties. Though the effects are subtle, it's known to improve mood and mental and physical performance. Studies have also shown that, in conjunction with L-theanine (a common amino acid found in green tea), caffeine can (slightly) boost working memory. But prior to this new study, which was conducted by researchers at Johns Hopkins and the University of California-Irvine, it wasn't known if caffeine has an enhancing effect on long-term memory in humans.

The answer, it would appear, is yes.

To figure this out, the researchers set-up a double-blind experiment in which volunteers who did not regularly eat or drink caffeinated products were administered either a 200 mg tablet (equivalent to a strong cup of coffee) or a placebo. The volunteers were asked to study a series of images — but interestingly, the tablets were taken not before, but five minutes after the study session.

The following day, both groups were tested to see how much information they retained. The test, a behavioral discrimination task, included images from the previous day, but also ones that were slightly altered and some new images altogether. Results showed that members of the caffeine group were able to correctly identify the images as being "similar" to the previously viewed images as opposed to just saying they were identical. It was an effect that lasted for at least 24 hours.

This ability — called pattern separation — allows us to recognize the differences between two similar but not identical items. The researchers say it reflects a deeper level of memory retention.

http://io9.com/how-caffeine-can-boost-your-memory-1500213465
 
I bet they would get even better results if they tried this with methamphetamine.
 
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