Stimulants Possible Amphetamine overdose resulting in damage to nervous system, need input.

[farnorth]

Hello everyone,

After some searching, I decided to use this forum to try to find some input and advice on my situation.

Monday night I aquired 2 grams of what was supposed to be cheap coke. It being cheap, I know it was cut and accepted this no problem. Not knowing purity is a huge issue here, still. I have what was leftover that I could examined to help any possible treatment a doctor could offer.

Anyways, came home and started my session for the night. I've done quite a bit of coke and have never had issues with going overboard, so I usually don't measaure precise dosages. 2 grams in a night has never been an issue.

After 2 or 3 lines, it became apparent this was super speedy shit based on 1 previous meth session. Felt like it was mostly speed actually, with very little if any coke.

Because of my ignorance and zero previous research on amphetmine, i was treating the powder like the coke i usually get. This was a mistake.

I went entirely overboard, using somewhere around 500-700mg in the first 15 hours, dosing probably twice an hour, small bumps. I was super wired and sweating buckets. Definitely experienced amphetamine psychosis. Hearing faint voices, sounds, slightly hallucinating, basically freaking out. Thought I had possibly brought out some underlying schizophrenia. Was up for somewhere around 40 hours before being able to sleep for 5-6 hours. Then, like a dipshit went right back to it when I woke up, using another 200-300mgs which wired me for another 20 hours or so. The schizophrenic like symptoms were more than likely due to the sleep deprivation. 5 hours of sleep in 4 days.

Anyways, throughout this process I was not being responsible at all. Was not keeping properly hydrated, not keeping myself from overheating, etc. Afterwards when coming down, my entire body felt completely beat up due to not eating or drinking while putting this much stress on the body. Was severely tweaking during this time.

5 days later I'm somewhat back to normal. Still having issues sleeping normally.The voices, hallucinations, etc are all gone. Still feel way off in my mind. Feel like I'm stuck in a slightly stimulated state, almost feels like the speed brought out some anxiety. Not my usual relaxed, level headed self. Can't think 100% clearly, balance is little off, and just a general empty feeling in the head. Feels like a chemical imbalance. Doing some research, I've found that these are all symptoms of amphetamine psychosis and usually relieve themselves in time. 10-30 days sometimes, with a small chance of never going away.

I have no illusions about this whole episode doing damage to the brain with those high dosages and general irresponsibility , I can feel it. Looking for people experienced with these types of situations to give input on how severely I fucked myself up and what I can do to help the situation before I go see a doctor. Any input is appreciated.

 

[Pineappleexpress42]

I've exprenced Phycosis with k6 a synthetic marijuana. I've freaked out on weed but never nearly as much as k6. It left me with a loss of reality and derealization, I feel it will never go away and doctors don't know what to do. I can't say much for phycosis under amphetamines though. Try to forget about it and go back to your normal life. I know the more I concentrate on the "phycosis" I'm still under the more paranoid I get to the point I think I have skitz.

 

[farnorth]

I'm completely in touch with reality, and don't feel like my thought process has been affected. It's hard to explain, but it's just a cloudy feeling, a little dizziness and imbalance, and not being able to relax. Feels like I'm still up, but at the same time feels like I need the rest of a good nights sleep but persists after 2-3 nights of sleeping normally.
Thanks for the reply and good luck

 

[Pineappleexpress42]

Thanks. So you have slept for 3 nights? If you can't fall asleep take dyphydramamine. If it continues like you said 10-30 days all I can say is doctor?

 

[sekio]

I have no illusions about this whole episode doing damage to the brain with those high dosages and general irresponsibility , I can feel it.

This kind of experience happens quite commonly with stimulants (and to a lesser extent psychedelics).

Most people who claim they can "feel" neurotoxicity actually don't have either evidence nor the symtomology of actual nervous system damage. And quite a lot of people who do suffer physical brain damage (stroke, etc) are not aware of it, aside from "something is seriously fucking wrong".

Brain damage from amphetamine usually requires chronic high-dose abuse (>100mg every day for months) or single massive doses that result in overheating/blood clots (very very unlikely).

Do remember that amphetamine has a 12-14 hour half life, so a large dose will remain active in your body for quite some time.

Most of the "damage" you're feeling comes from simple stress (aided by sleep deprivation) and monoamine depletion. Eat a high-protein meal or two and get some good, non-drugged sleep, and you should feel much better in a week or two.

Try to forget about it and go back to your normal life.

This is really the best advice to take.

 

[farnorth]

Ya, I've slept but it's been rough, and I've had to use melotonin, Excedrin pm, and even trazodone to help me relax enough to sleep.

Best case scenario is these are the classic symptoms of amphetamine psychosis and they will reside within a month at most. Worst case is I fried my central nervous system a little and will never feel normal.

 

[sekio]

It's still a massive dose, but lucky for you amphetamines can be fairly forgiving once you get past the long half-lives. People have survived ~2g MDMA IV'd before, less than a gram of amphetamine (though it's a dumb, dumb idea) is probably not going to cause permanent damage.

 

[farnorth]

This kind of experience happens quite commonly with stimulants (and to a lesser extent psychedelics).

Most people who claim they can "feel" neurotoxicity actually don't have either evidence nor the symtomology of actual nervous system damage. And quite a lot of people who do suffer physical brain damage (stroke, etc) are not aware of it, aside from "something is seriously fucking wrong".

Brain damage from amphetamine usually requires chronic high-dose abuse (>100mg every day for months) or single massive doses that result in overheating/blood clots (very very unlikely).

Do remember that amphetamine has a 12-14 hour half life, so a large dose will remain active in your body for quite some time.

Most of the "damage" you're feeling comes from simple stress (aided by sleep deprivation) and monoamine depletion. Eat a high-protein meal or two and get some good, non-drugged sleep, and you should feel much better in a week or two.



This is really the best advice to take.

Wow, this is very reassuring. This is what I was leaning towards as I don't really feel like I have brain damage. Just a little off, not my normal self. Have had this with other drugs in the past and it's always relieved itself. Only reason this time is different for me is because of how terrifying the experience was. Is profuse sweating caused by overheating? I don't remember feeling overheated at all, but i did sweat gallons.

You don't think those dosages were extremely high? Most people talk about 200mg being a massive dose of speed. I know purity is an issue and i know my dealer wouldn't sell 100% speed and call it coke. No way to know how much actual speed was used, but the amount of powder i put up my nose has me worried. 1g of pure amphetamine over 15 hours would be a serious issue for someone, yes?

Regardless, if these symptoms are not gone within a week or so, i will see a professional.

Thanks for the input Sekio

 

[sn0wburt0n]

don't buy from that guy again.

200mg seems like a massive dose of speed.

would try and give yourself a lot of good healthy loving after that binge. vitamins, eating well and exercise for a couple of weeks before doing anything illicit.


see how you feel after that, then see a dr.

 

[Swimmingdancer]

It's very rare to get permanent damage from doing it for just a couple days, even in high doses. Most symptoms will be temporary and are alleviated by time, sleep/rest, proper nutrition and hydration. Don't worry too much, I doubt you are going to feel this way forever. Just chalk it up to a learning experience and try to be more careful in the future.

Even with extreme stimulant psychosis, studies have reported ~65% of people recover within 10 days of stopping amps and ~80% recover rate within a month after amphetamine cessation. People with severe psychosis lasting more than a month are said to only have around a 10% rate of full recovery. You said your psychosis is already gone and it's only been 5 days, so I think that's a great sign. Feeling off, "foggy" and anxious is very normal when recovering from high doses of stimulants. Take some vitamins, eat healthy, drink plenty of water and get lots of sleep and I bet you'll be feeling a lot better in a few days.

 

[farnorth]

It's very rare to get permanent damage from doing it for just a couple days, even in high doses. Most symptoms will be temporary and are alleviated by time, sleep/rest, proper nutrition and hydration. Don't worry too much, I doubt you are going to feel this way forever. Just chalk it up to a learning experience and try to be more careful in the future.

Even with extreme stimulant psychosis, studies have reported ~65% of people recover within 10 days of stopping amps and ~80% recover rate within a month after amphetamine cessation. People with severe psychosis lasting more than a month are said to only have around a 10% rate of full recovery. You said your psychosis is already gone and it's only been 5 days, so I think that's a great sign. Feeling off, "foggy" and anxious is very normal when recovering from high doses of stimulants. Take some vitamins, eat healthy, drink plenty of water and get lots of sleep and I bet you'll be feeling a lot better in a few days.

Most of the symptoms are gone at this point, except a little fogginess and just a general off feeling.

I just really worry that I may have overheated and caused some damage, but I've been told this kind of damage would go a lot further than a foggy feeling.

 

[tyrael]

....Most people who claim they can "feel" neurotoxicity .....

I've heard this from people also - in the sense where they're sitting there smoking a pipe and come out something along the lines of "oh may I can feel the damage". I've heard about serotonin, GABA and dopamine receptor too. Regardless of the neurotransmitter, it's highly doubtful one could "feel their neurons being damaged"

......
Brain damage from amphetamine usually requires chronic high-dose abuse (>100mg every day for months) or single massive doses that result in overheating/blood clots (very very unlikely)....

Of course I don't disagree, however I am extremely well stuck of the impression (that is, all my studies/research/conversations with GPs, those specialised in the drug / drug rehab field. Basically everything I know leads me to believe) irrespective of ones dose*, an element of neural (amongst others) toxicity will
be experienced! And of course depending on the locate of the damage if this can be recovered (eg, the body cannot perform any sufficient** neural damage/replace. others areas can!)

Most of the "damage" you're feeling comes from simple stress (aided by sleep deprivation) and monoamine depletion. Eat a high-protein meal or two and get some good, non-drugged sleep, and you should feel much better in a week or two......

Maybe not "most" but I definitely well agree with you sekio. I think many people don't think about the more distal effects it can induce.

You mention specifically monoamine depletion - which I kind of a general statement. Can you point me toward where I can more about this?



* clearly I'm implying doses which would be considered recreational.

** of course one could argue, suggest, etc possible reaction (read: not recovery) to damage of brain matter such as forms of neural-plasticity, possible affects produced by common neural support cells such as the oligodendrocyte, astrocytes and others (too late to think of the others! Lol)

 

[tyrael]

.....Even with extreme stimulant psychosis, studies have reported ~65% of people recover within 10 days of stopping amps and ~80% recover rate within a month after amphetamine cessation. People with severe psychosis lasting more than a month are said to only have around a 10% rate of full recovery. You said your psychosis is already gone and it's only been 5 days, so I think that's a great sign.....

This is really interesting, specifically since I haven't really ever been told or have seen any specific figures regarding stimulate use (and/or over-use) and the lingering mental affects after extreme events - an OD, an endued psychosis, etc!

You also talk about "recovery", can you specify what you mean by this? As in after said period there are no lingering mental effects nor any cognitive impairments? Or are you referring to a more physical recover?

 

[farnorth]

Update:
Have definitely noticed some cognitive and memory issues.
Hard time recalling simple things from before the night this all went down, and had to recount a stack of cash 3 times this morning due to scatter brain. Aside from this, starting to feel normal so hopefully this is just a little shock to the brain from such a large dose.
Giving it some more time before I see a neurologist. I'm figuring if I'm truly worried about it, I can just have a full evaluation including CT, MRI, all that kinda shit.

 

[Supsup]

Hey I'm goin through the EXACT same thing went on a 4 day bender on mamph no food no sleep ALOT of alcohol barely any water this was about 15 days ago I'm slowly starting to get my mind together although I felt as if I may have caused perm damage in the beginning I believe now was just caused buy beating my body up n it needs some time to get over it starting to feel 100% again I reckon ull pull up alright. Thanks for everyone's input phas Deffinatly put my mind at ease

 

[Tricsta]

One year i did 1 week on no nothing... then 1 week sleep, drag my arse out of bed to sit on loo, to the fridge for milk and cheese for the whole year. I have issues apparently. Don't do it, as hard as it is, force yourself. Little bite of a sand which, biscuit, glass juice etc whilst you are high.