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Opioids plugging vs IV

plugging oxy is alright idk what the BA (bioavailabilty) is, though, i'd look that up before doing it
 
The best way to take oxycodone is orally.

There is no advantage to IV, a 13% gain in BA is no reason to be injecting and as you said, you're running out of veins. This is the reason why.

What are you using to filter your IV oxycodone??
 
I wouldn't bother plugging.... IV isn't that much better.... if you wanted to be safest outside of IV and not orally, do a method to break it down and snort.
 
i get a rush comparable to dilaudid when injecting oxy it's just like 2/3 as intense but i've heard plugging works similar to IV i was just wondering if thats true
 
Are you serious? I've never met anyone who got a rush from oxycodone, even the most hardcore addicts that I know who usually slam are smart enough not to IV oxycodone and always take them orally, they don't even waste time snorting them. They all say the same things: there's no rush, there's no point, many claim that the duration of action is reduced pretty significantly, it's no more intense than the peak of an equal dose taken orally, etc.

Can you describe the "rush" you get from oxycodone, and also describe how a dilaudid feels to you? Are you absolutely sure you're not just confusing immediate onset with a bonafide rush?

Silenced said:
I wouldn't bother plugging.... IV isn't that much better.... if you wanted to be safest outside of IV and not orally, do a method to break it down and snort.
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How is that safer? Snorting the fine particles of a powdered pill into your lungs is not going to be a good thing in the long term, Silicosis was a major concern with the octagonal Opana ER that people were snorting.
 
it starts by making my throat and neck tingly then a warmth runs up my spine to my brain the i feel overwhelmed with euphoria
 
But no allergic reaction? Like you don't puff up or have any constriction in your airways do you?

Definitely skip the opioids altogether if possible, and if not, then tell your doctor about any adverse effects including histamine induced allergic reactions.
 
Plugging dilaudid is great but honestly I would take half your dose rectally (for the fast onset and longer duration) and half intranasally in an aqueous solution (also increases onset and euphoria).

I like plugging with dilaudid because if you have the tolerance for it, you can pack over a whopping 333mg/mL in water.

So if you aren't concerned with "wasting" drugs and you have a tolerance, then just rectally administer a hefty dose of hydromorphone, not too high, start low. Then titrate your dose up so you know how much you should be plugging all at once, it will take trial and error.
 
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I've have friends that've had great success with plugging hydromorph...however, I'm just too much of a needle/rush fiend. Though, the amount of pain my hands are in today from shooting coke for 2 days is starting to make me reconsider... (not really)

I'm fucked up.
 
I've heard of many who've said IV oxycodone gave them a rush. Smoking OGs gave me a rush not unlike smoking H(please don't turn this into a debate about wasting drugs,). Bioavailability is 50+% up to 87%. Those that get 87% might not notice much except a fast onset and rush, while those that get 50-60% it may be twice as strong.

Plugging isn't that much more effective than oral, according to some studies( http://www.ncbi.nlm.nih.gov/pubmed/1485370 and http://www.ncbi.nlm.nih.gov/pubmed/7818116) though it did have a longer duration. I think with the old oxycontin they did find that had slightly higher(+10% ) peak concentration rectally than orally.

It strange how so many say rectal morphine, hydromorphone, and heroin work almost like IM. Yet a lot of studies I've read that they don't have much higher bioavailability or speed of onset than orally, sometimes lower and slower. Yet I've heard many people, online and in real life, say that rectal is almost like IM. Maybe it's the preparations inactives and the amount of shit up there that alters the bioavailability and speed of onset?

Besides snorting(fucks up your nose/lungs)/smoked(burns up some, doesn't last long, hard on the lungs), which are not without their own problems, the best way is to drink some grapefruit juice and take it either orally or sublingually(if you can stand the taste). Still, nothing can replicate IV with modern technology.
 
mrflowers00 said:
i get a rush comparable to dilaudid when injecting oxy it's just like 2/3 as intense but i've heard plugging works similar to IV i was just wondering if thats true
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I disagree. There is no rush to be had with oxycodone. I mean the drug hits you fast when you IV.. but that's not the rush people desire. It's a joke compared to a heroin rush and the laughing stock of the party compared to the freight train cocaine rush.
 
THC2LSD said:
I've heard of many who've said IV oxycodone gave them a rush. Smoking OGs gave me a rush not unlike smoking H(please don't turn this into a debate about wasting drugs,). Bioavailability is 50+% up to 87%. Those that get 87% might not notice much except a fast onset and rush, while those that get 50-60% it may be twice as strong.

Plugging isn't that much more effective than oral, according to some studies( http://www.ncbi.nlm.nih.gov/pubmed/1485370 and http://www.ncbi.nlm.nih.gov/pubmed/7818116) though it did have a longer duration. I think with the old oxycontin they did find that had slightly higher(+10% ) peak concentration rectally than orally.

It strange how so many say rectal morphine, hydromorphone, and heroin work almost like IM. Yet a lot of studies I've read that they don't have much higher bioavailability or speed of onset than orally, sometimes lower and slower. Yet I've heard many people, online and in real life, say that rectal is almost like IM. Maybe it's the preparations inactives and the amount of shit up there that alters the bioavailability and speed of onset?

Besides snorting(fucks up your nose/lungs)/smoked(burns up some, doesn't last long, hard on the lungs), which are not without their own problems, the best way is to drink some grapefruit juice and take it either orally or sublingually(if you can stand the taste). Still, nothing can replicate IV with modern technology.
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I'd say lots of trollish blighters find it funny to have people stick stuff up their ass because they told to on the interwabs.
 
mrflowers00 said:
how can you fit 333mg of diladid in 1 ml of water?
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L0dgik said:
Doubt he meant 1ml of water
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The Merck Index says 1 parts of hydromorphone hydrochloride is highly soluble in 3 parts of water.

This means hypothetically 1cc = 1mL = 333mg hydromorphone, or one gram of hydromorphone in 3mL.


mr.scagnattie said:
Yeah, comparing the hydromorphone rush to oxy is pretty crazy in my opinion..hah. It's a night and day difference..one's like eating a 50 dollar steak..and the other's like cat food...
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^
 
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