edgewise1
Bluelighter
Ha! You could easily take that many pills up the jacksy (in solution, of course) but it's worth bearing in mind plugged drugs hit a helluva a lot harder than oral doses and I suspect that with such massive doses the seizure risk would be even higher however high your tolerance is. Along with the fact that tolerance is neither here nor there when it comes to seizures as you mentioned. I would personally advise against plugging such large amounts - maybe try halving your dose and see how that sits if you go for the tradesman's entrance option![]()
Does the bioavailabilty have anything to do with the onset and strength? If I remember correctly there is only about 3% difference between oral and anal.