Plugging Heroin

[Beefy]

Hey, I recently heard about a friend of a friend doing this. From what this person said, it seems he gets higher than shooting it IV. I was wondering if anyone has done this, if it's suggested or if u have 2 bags, you're better off just using IV than plugging it. Thanks

 

[DoctorShop]

I don't use anymore. If I did though I'd probably just shoot it.

In saying that though, I know of people who use the slightly larger syringes with no needle tip. They draw the solution up, stick it up their bum and release the solution. Apparently it kicks in quite quickly due to all the nerve endings up there.

 

[Tryptamino]

It does not get you higher than IVing, since the bioavailability of IV is 1% higher than rectal (IV = 100%, rectal = 99% ) and the onset is a bit slower, however it is a safer ROA, than IVing by FAR and many former IV users of various drugs choose to plug it instead, myself included, although I have personally never plugged heroin, however I have plugged morphine, oxy and hydrocodone, crystal meth/desoxyn, adderall/dexedrine, MDMA, cocaine, and a few others, and it is definitely the best ROA for most drugs, seeing as it has essentially the same bioavailability as IV yet it is less immediately dangerous to the body than almost any other ROA aside from oral. It will not give as intense a rush as IV or smoking, but it's long-lasting and healthier. I recommend you switch from IV to plugging wholeheartedly, save yourself the possibility of some serious bodily harm.

Use as small a syringe as possible (no needle, obviously), prepare the exact same size shot as you would usually do, lube up the syringe, stick it up your behind, and pull the plunger. Make sure the syringe is at least 4 inches in.

 

[tentram]

^4 inches is a little far. you needn't go any further than 2-3 knuckles deep, really - so two inches. the difference in high is going to negligible is there is only a 1% difference in BA as well. so it's essentially going to be the same.

and pull* the plunger.

*push.

 

[Mr.Scagnattie]

Depends what you're looking for out of your dope.. if you're a rush chaser, (like I am.. it's basically the only reason I fell in love with heroin).. you just don't get it via any other way other than IV. I'd still never advocate one to do it.. but when people say they can't use any other way, despite the safety, despite the high BA of plugging, etc.. I get it. Some of us just love the rush and the entire act of IV'ing way to much. But, if you can plug dope and feel satisfied, more power to you. I wish I could.

 

[helium-4]

It does not get you higher than IVing, since the bioavailability of IV is 1% higher than rectal (IV = 100%, rectal = 99% ) and the onset is a bit slower, however it is a safer ROA, than IVing by FAR and many former IV users of various drugs choose to plug it instead, myself included, although I have personally never plugged heroin, however I have plugged morphine, oxy and hydrocodone, crystal meth/desoxyn, adderall/dexedrine, MDMA, cocaine, and a few others, and it is definitely the best ROA for most drugs, seeing as it has essentially the same bioavailability as IV yet it is less immediately dangerous to the body than almost any other ROA aside from oral. It will not give as intense a rush as IV or smoking, but it's long-lasting and healthier. I recommend you switch from IV to plugging wholeheartedly, save yourself the possibility of some serious bodily harm.

Use as small a syringe as possible (no needle, obviously), prepare the exact same size shot as you would usually do, lube up the syringe, stick it up your behind, and pull the plunger. Make sure the syringe is at least 4 inches in.

Please cite your source for the bioavaliability for rectal administered heroin. I have yet to find anything supporting such a number, and it also seems a bit high as well imo. The bioavaliability of rectal administration isn't always close to IV, or the next optimal choice next to parenteral routes of administration (IV, IM, etc.). For example in the case of methadone, rectal administration is less effective than IV, nasal, and oral administration. I'm hoping you aren't assuming the rectal admin. is always a superior choice, when in reality it isn't

 

[Swimmingdancer]

It does not get you higher than IVing, since the bioavailability of IV is 1% higher than rectal (IV = 100%, rectal = 99% ) and the onset is a bit slower, however it is a safer ROA, than IVing by FAR and many former IV users of various drugs choose to plug it instead...

It will not give as intense a rush as IV or smoking, but it's long-lasting and healthier. I recommend you switch from IV to plugging wholeheartedly, save yourself the possibility of some serious bodily harm.

I agree with everything you said except for the bioavailability being 99% with rectal heroin. I have never seen any published numbers in the medical literature on the BA of rectal heroin, it hasn't been studied much. (Please correct me if you got that statement from somewhere and weren't just making an assumption though )

Honestly I don't even understand how they determine the BA of heroin. Are they checking the morphine and/or 6-MAM levels after heroin administration? If you go by the BA of heroin itself, then IM has a BA of 380% [source], and according to this very small study, the BA of heroin itself after rectal and oral administration was 0%. Heroin is a pro-drug for morphine and 6-MAM, so the actual heroin levels are not responsible for the effects - the levels of morphine and 6-MAM are more important. Regardless, bioavailability is not a measure of the strength of a high, just the total absorption. Something could have an excellent-sounding BA, but be absorbed slowly, creating a weaker but longer-lasting high, for example. And BA is not set in stone, it varies greatly from person to person (and even within the same person).

No ROA for heroin is quite comparable in effect to IV injection, as you won't get that same rush that is caused by heroin rapidly entering the brain and being converted to 6-MAM. But rectal administration definitely gets many people strong effects and is preferable to injection for numerous reasons.

 

[my84firebird355]

I don't think I could ever stick a syringe up my ass.

swimmingdancer - I think you're incorrect in saying that IM has a bio-availability of 380%. If you read your source more carefully 380% +/- 157% was the mean BA for diacetylmorphine, monoacetylmorphine, and morphine.

 

[Mr.Scagnattie]

A stat like 380% +/- 157% is basically just saying, "I have no fucking clue."

 

[Pagey]

I've never IV'd or plugged but from what I've heard, plugging is the closest you'll get to the rush and euphoria felt when you IV in terms of all the other ROAs. And it's definitely safer to plug than IV, it's really much better to avoid IV'ing at all costs so yeah please consider switching to plugging.

 

[Swimmingdancer]

swimmingdancer - I think you're incorrect in saying that IM has a bio-availability of 380%. If you read your source more carefully 380% +/- 157% was the mean BA for diacetylmorphine, monoacetylmorphine, and morphine.

I don't think so. It says:

Intramuscularly administered diacetylmorphine (200-250 mg) exhibited linear diacetylmorphine, monoacetylmorphine, and morphine kinetics and resulted in sustained diacetylmorphine exposures (bioavailability, 380% 157% [mean SD])

I think that implies they are talking about the BA for diacetylmorphine (heroin).

A stat like 380% +/- 157% is basically just saying, "I have no fucking clue."

Not really, nearly all BAs have a large +/-, it just shows there was large variability from person to person.

Anyway, I'm still confused as to how published BAs for heroin are generally determined. I've been reading a bunch of studies and it's hurting my brain right now 8(. Many just appear to be determining an "estimated" bioavailability based on the total excretion of morphine in the urine within a set time period.

My conclusion is that when it comes to heroin it's really just wisest not to obsess over the numbers, and to find what works for you personally, (since everyone is so different anyway). I think plugging is a viable alternative for many people and has a lot of advantages.