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Pick the next lysergamide RC

Which ever one is like LSD but but like half the duration.

The closest thing to such would be LSM....the few people I know who have tried it only had good things to say about it...and it's around 6 hours in duration...

I tried what was purported to be (and I have good reason to beliveve it was) ALD-52....I noticed no appreciable difference to LSD..

I like how Hamilton Morris' nickname of LSZ has stuck...Pickard had some fancy trade name for it...diazedine or some such...
 
That's pretty much the opposite of what i've read about LSM. And diazedine is a (more or less accurate) abbreviation of the chemical name.
 
Yes, but IMO it makes a lot more sense to keep names consistent with the abbreviation for LSD or -LAD.

I like λ (lambda), but plenty of people might not know what the fuck it is and before you know it they would be calling it half-life. Also I don't have an explanation for the name λ whatsoever.
 
And as for which one I'd pick - 6-allyl-6-nor-lysergic acid 2,4-dimethylazetidide aka al-lsz, don't even care if it would be active

izxm2w.png

I started thinking about AL-LSZ last night, and became a bit obsessed with the idea. I'm guessing it would be even harder to synth than either Al-LAD or LSZ, so maybe it won't get synthed. Maybe it would skirt the new UK ban? I think it must be active, since both AL-LAD and LSZ as variants on LSD are active at very similar doses.

While we're at it, let's try ETH-LSZ and PRO-LSZ too!
 
I don't know why it would be particularly difficult, it just seems like a bit of extra work to do both modifications / substitutions yes. AL-LSZ sounds very realistic to expect from what I pick up.

If it were up to me, I'd check if the changed UK laws to verify if indeed haloalkyl substitutions are not specified... but seems like fluoroeth-lad / FE-LAD / EF-LAD would be pretty nice... the allyl of AL-LAD makes me suspect that a δ- / electronegative group there wouldn't be a problem and it would sterically be a small step from ETH-LAD. Never heard about it though. fluoromethyl and fluoropropyl might also be ideas, who knows they may change duration and other properties of the trip?
At extreme potencies it may not really matter all that much but I remember from cannabinoids like AM-2201 that even-number halogenated carbon chains were not preferred since something like fluoroacetic acid is not a nice metabolite... but uneven carbon number chains should be fine, like fluoromethyl or fluoropropyl.
 
Really interesting ideas Solipsis.

Do you think we should hush up about these ideas and leave it to the production chemists so that we don't prematurely inspire lawmakers?
 
Really interesting ideas Solipsis.

Do you think we should hush up about these ideas and leave it to the production chemists so that we don't prematurely inspire lawmakers?

I've never heard about law makers reacting to something a dude said on a forum, only to actual developments in a dull and unimaginative way.

On the other hand I have heard about 'production chemists' getting ideas off the internet, although I've only seen that mention in the context of ill-advised and non-reviewed ideas. But yeah as far as the actual genuises go, we should totally leave it up to them, I don't really have any delusions about it.

If you still think it's best deleted I have no problem with that ;p
 
wish it would be ALD-52. but i think it will be banned soon in the UK - however this was recommended back in july..... dunno when or if they will act on it.

supposedly it does break down to LSD, but less visual distortions or whatnot?

i heard the "orange sunshine" acid sold back in the 60's was actually ALD-52. but what do i know.
 
nah this speculation is too much fun. But if someone else thought it should be deleted I would also have no problem.




What would an acetate of Al-lad look like? where would the acetyl group go?

replace the r1 nitrogen as with ald-52.

Out of the ones that are known I'd like to see (in order):
ALD-52
ETH-LAD
PRO-LAD

Not as interested in r2 sub LSx's when the r6 subs seem to work so well.
 
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It's inactive, though...?

You're right it probably is, but it should be noted the study that established this is quite old and if it turns out the researchers just missed out on it the first time through, well, I'll let the binding profile data speak for itself. Looks fairly promising to me, assuming it is indeed active of course =D Guess we'll just have to wait and see...

0Tp4coV.png


from Nichols et. all
 
I don't see why not? Although I don't see why either as imo lsz didn't offer any particular improvements over the original? Not sampled yet just going by what I've read.
 
Yes that seems to be the consensus regarding LSZ. My one trial would have to agree, but I want to keep an open mind to exploring it for it's unique character. So far, it has a few differences vs LSD, but they are minimal and not specifically improvements. I guess one improvement over the original is it's quasi-legal status.

Not really any particular reason at this point that N-Acetyl-AL-LSZ would be worth exploring. We'd probably want to see AL-LSZ and N-Acetyl-Al-LAD first.
 
Im sorry, but this thread seems absolutely ridiculous. How can anyone commenting know the possible effects of any given chemical based on on composition alone. Even if there are trip reports for LSD-pip or ETH-LAD, how can any of you know the effects?

Honestly to me this sounds absurd. Theres a certain point where being a drug know-it-all goes to far, and this is it. Everyone who has commented on this thread is basing their desires on anecdotal reports or molecular composition that means next to nothing, other than letting us know its similar to another comparable chemical.

im ready to be flamed, but seriously. This all seems like pretentious nonsense.
 
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