Phenibut

[Allein]

I've taken the question over to BDD, looking at it Phenibut's main action is to bind to the GABA-b receptors, which would help with GHB withdrawal, but at higher doses there is evidence it binds to the GABA-a which is what Benzos do and clearly the effect that I'm interested in.

 

[scrooloose]

I've taken the question over to BDD, looking at it Phenibut's main action is to bind to the GABA-b receptors, which would help with GHB withdrawal, but at higher doses there is evidence it binds to the GABA-a which is what Benzos do and clearly the effect that I'm interested in.

Chok dee krap

Just had a look,be interested to see how it goes.

 

[Treacle]

Yeah, phenibut hits GABA-b receptors, whereas benzos hit GABA-a. Phenibut also causes very fast downregulation of receptors. It may work for a while, but you'll be left with withdrawals, then you'll need a phenibut taper. It might not even cover your symptoms - like benzos don't work too well for GBL/GHB/phenibut withdrawals. I'd honestly go on a benzo taper. You may just end up hooked on both.

 

[Allein]

From what I've read at higher doses it does have some action on GABA-a, I need to taper faster without increasing the risk of a seizure, the discomfort and anxiety are things I can deal with, I juts need off the Benzos ASAP, before I slip up in a big way and end up at square one.

I've seem someone withdrawn from GBL on Benzos and read about people withdrawing from Phenibut using Benzos so it seem it may well hit both a and b at some level, its juts the risk of seizure that has me worried. May be Valerian root would be a better bet but info is very thin on the ground.

Tapering is all very well but e are talking about months of slowly counting down the pills, its torture and I fear I may not make the finishing line, if I could CT I'd do it today WDs don't scare me as I'd know it was going to get better over time and anxiety is a way of life.

Even of alternate daily dosing ca ease a quicker taper it would be something, maybe I'll look at ensuring there is no dangerous interaction with Valerian root and be that guinea pig...whats the worst that could happen ....that was rhetorical.

 

[Treacle]

Valerian is unlikely to work, at all, with any benzo tolerance. I can say that benzos are crap for a serious G/phenibut withdrawal, and I'd bet the reverse is true. You might be able to alternate your days with both. Might. Just be careful.

 

[Allein]

Thanks Treacle, I'm on the last stretch of the Benzo taper and have no intention from deviating from the original schedule, that I laid out at the beginning.

Having read up on Phenibut, although there is little information it dos seem that it does have some GABA-a activity but there si an element of playing with fire here in that I could end up off the benzos but with another habit just as bad.

I've experimented with dosing over the last 3 days and found that about 1g gives a small potentiation to the Benzos and relieves the anxiety I am suffering towards the end of the day. I only ever dose either in the evening and regardless of my tolerance 2g is my limit or the lot gets flushed, the last thing I need is another taper to deal with.

Now I know the dosage its a strictly every other day thing at most and then only if I feel I need something as the end of the Benzo taper is always the worst, counting out and ever decreasing amount of tablets everyday when a big part of me is saying, fek it just this once, treat yourself and have a few extra.

I ain't complaining I got myself in and it's only me that can get my way out.

From what I've read people get into massive doses of Phenibut and can get into real trouble with it but in some countries its being widely sold as a "smart drug" along side stuff like Piracetam which I remember getting hold of way back in the early 90's because me and a friend had heard that it worked well with LSD, we did a big dose fek knows whether it worked, I mean we were on acid, hardly a place from which top make any kind of objective

 

[Treacle]

You sound fairly in control, so just keep tapering the benzos. If you do end up with a phenibut withdrawal, it won't last as long and won't kill you - so that's something. The thing is, GABA-b withdrawals will sometimes kick in - despite continuing to use the same amount. If it does, then you may confuse it for benzo withdrawal, and increase both. Again, be careful and stay strict with yourself. This won't end, if you keep having little treats. I know this from personal experience. Those are for after you've kicked it, and can handle occasional use.

 

[Meat Bag]

Thanks Treacle, I'm on the last stretch of the Benzo taper and have no intention from deviating from the original schedule, that I laid out at the beginning.

Having read up on Phenibut, although there is little information it dos seem that it does have some GABA-a activity but there si an element of playing with fire here in that I could end up off the benzos but with another habit just as bad.

I've experimented with dosing over the last 3 days and found that about 1g gives a small potentiation to the Benzos and relieves the anxiety I am suffering towards the end of the day. I only ever dose either in the evening and regardless of my tolerance 2g is my limit or the lot gets flushed, the last thing I need is another taper to deal with.

Now I know the dosage its a strictly every other day thing at most and then only if I feel I need something as the end of the Benzo taper is always the worst, counting out and ever decreasing amount of tablets everyday when a big part of me is saying, fek it just this once, treat yourself and have a few extra.

I ain't complaining I got myself in and it's only me that can get my way out.

From what I've read people get into massive doses of Phenibut and can get into real trouble with it but in some countries its being widely sold as a "smart drug" along side stuff like Piracetam which I remember getting hold of way back in the early 90's because me and a friend had heard that it worked well with LSD, we did a big dose fek knows whether it worked, I mean we were on acid, hardly a place from which top make any kind of objective

Those dosages are ridiculously high. Phenibut can cause fatty liver in dosage over 7g. And it may be (and possibly is) hepatotoxic in dosage over 1g.
Phenibut does not have GABA-a activity in therapeutic dose, and therapeutic dose is 250-500 mg. Recommended maximum single dose is 750 mg.
The best anti-anxiety regimen is 250 mg 3 times a day for 2, maximum 3 weeks. With this regimen you don't need to taper it off and it does not cause much GABA downregulation.

And yes, it works perfect with LSD! Took 500 mg 30 min. before dosing with LSD and you have virtually zero chance to have a bad trip! And it's does not affect any of the LSD effects, unlike benzos and antipsychotics.
One time I take 500 mg. after I started to panic heavily on LSD and after 30 min. I was calm and happy. Virtually zero anxiety, very good humor. I even managed to go outside and pick up some beer in local pub (and the public there was very unfriendly). Basically it was my first good trip on psychedelics.

 

[Treacle]

250mg wouldn't affect a baby. Doses under one gramme don't seem to produce much of an effect - certainly not as effective as a benzo. Anyone else find it works in ridiculously low doses? The reason it won't downregulate receptors as fast, is because it's not really doing anything. Sources for the apparent liver issues?

 

[scrooloose]

I've never heard of liver issues with phenibut. Anything under 1.5 grams,for me anyway is a waste of time,as in no effect.

 

[Meat Bag]

Nah. no sources. Only instruction from the box. There are some researches, but they are in Russian and I don't think, that they are available on the net. (pretty old, made in soviet era)
250 mg is fine! 250 mg is a standard dose of one tablet. 20 tabs in a box. Doctors always prescribe 250 mg 3 times a day. It's not recreational dose and it wouldn't get you fucked up. But I'm pretty sure it HAS the effect. Higher doses (up to 750 mg) used to threat alcohol withdrawal.
It's just a clue, but maybe RC phenibut powder, that sold in US and EUR is less potent than pharmaceutical grade phenibut tabs, that sold in RUS? Cut with something or any other reason? Because I could definitely feel some minor effects from 250 mg. tab. Two 250 mg tabs give some real effects and three 250 mg tabs make me fucked up a little. (blurred vision, slightly slurred speech, etc.)

It also cause eosinophilia with the large doses. (source only in Russian http://www.rlsnet.ru/tn_index_id_5320.htm )

 

[Onandoff]

I got 100g of phenibut(primaforce) coming my way. Do I have to use gel caps/veggie caps for this or can I just toss and wash it down with water or juice?
I basically want to use this once in a while to fix my sleeping pattern and getting off of my kratom habit. I don't have any tolerance to benzos... would 500mg be a good starter dose?

 

[scrooloose]

You will find 500mgs too weak and redose. Just go for 1.5 grams,mix it in juice,water ,whatever.Takes ages to kick in,two to four hours proper. My recreational dose is 2 to 2 and a half grams. The taste isn't too bad,just bitter.I'm assuming you have bulk powder. See how you get on and remember how long it takes to work if you use it for sleep.Don't redose because you think it isn't working. 1.5 grams should give you an idea what it's about. I've been reckless with it before,using on consecutive days.No more than two days in a row.

 

[naughtynicknails]

Nah. no sources. Only instruction from the box.

My phenibut came with the recommended doses at 500mg to 3000mg daily

I take 1200 - 2100mg.. but not every day.. I was addicted to it for about a year and the withdrawals are naaasty.

 

[Treacle]

I got 100g of phenibut(primaforce) coming my way. Do I have to use gel caps/veggie caps for this or can I just toss and wash it down with water or juice?
I basically want to use this once in a while to fix my sleeping pattern and getting off of my kratom habit. I don't have any tolerance to benzos... would 500mg be a good starter dose?

Juice/water is fine. It's got a bitter, citrusy taste, which is likely to make you screw your face up, but I've tasted much worse. 1.5 grammes is a good place to start. Don't jump in at over 3 grammes, like I did, because that gave me a panic attack - weirdly enough. It can be quite odd stuff.

 

[Mr. Tambourine Man]

I recently ordered some phenibut for the purposes of occasional use as an anxiolytic/social lubricant. It sounds like it would come in handy for stressful social situations such as public speaking and family events, which is what I intend to use it for.

Having read all the horror stories, and given my partiality to GABAergic drugs, I am setting my limits beforehand. The plan is no more than 1-2 uses per week, with at least 3 days between uses. I also don't intned to mix it with alcohol or other GABA depressants. Should I use twice in a week for more than two weeks, or have any control issues, I'll give this stuff a long break (or toss it as appropriate). I've been through benzo WD, and have no desire to be in that position again.

I am usually quite good at sticking to a use schedule if I set it before hand, even with opiates. Assuming that I follow these rules, does this seem like a safe approach?

 

[Acidtek]

atm23, from your posts it seems like you are so close to beating your benzo issues, I'm glad to see another person manage to tame the beast! I only used 300mgs a day for a year and I finished my taper nearly 8 weeks ago! I must admit I've used about 5 etiz in about that time, but for me they are not moreish like proper benzos! Keep up the hard work atm23, you've nearly conquered it now mate! Ecstatic for you bud!

 

[Treacle]

I recently ordered some phenibut for the purposes of occasional use as an anxiolytic/social lubricant. It sounds like it would come in handy for stressful social situations such as public speaking and family events, which is what I intend to use it for.

Having read all the horror stories, and given my partiality to GABAergic drugs, I am setting my limits beforehand. The plan is no more than 1-2 uses per week, with at least 3 days between uses. I also don't intned to mix it with alcohol or other GABA depressants. Should I use twice in a week for more than two weeks, or have any control issues, I'll give this stuff a long break (or toss it as appropriate). I've been through benzo WD, and have no desire to be in that position again.

I am usually quite good at sticking to a use schedule if I set it before hand, even with opiates. Assuming that I follow these rules, does this seem like a safe approach?

Sounds like a pretty good plan. Just don't do massive doses, because that can also downregulate receptors.

 

[Onandoff]

Thanks for the dosage guidelines. I got my phenibut powder(primaforce) and it smells like stinky piss stain lol. Is this normal?
I took 1.5g before bed the other night but the effects were rather subtle. Is it possible this brand could be carrying bunk batch?

 

[rolls_]

Yes it smells terrible and tastes even worse. 1.5 grams isn't a huge dose, I would have thought you would feel more than a subtle effect but as you slept through it it is possible you just didn't notice.