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  • Trip Reports Moderator: Cheshire_Kat | M!$ter-ED

Phenibut- Methadone OD Experience

StarshipHigh

Greenlighter
Joined
Jan 4, 2026
Messages
1
Just wanted to post my experience so others are aware of the danger.
In 2017 I had been Methadone Maintenance for going on 2 years. At that point I hadn’t gotten my shit together and was still using various things.
I was perscribed 105mg of Methdone for 18ish months at the time.

I remembered when I was in college using phenibut to potentate Kratom. For me it was very effective. An additional plus was I didn’t have to worry about it popping on my drug test.

I bought around an ounce of phenibut HCL and was using it in doses between 1-2 grams for about a week. I was taking it literally just before taking my methadone dose. In my mind this was completely safe. I had a steady tolerance to the methadone dose as I had been on it for 18 months. In my past experience with Kratom, I knew it potentiated Opiates. However, I didn’t think it was to the degree benzodiazepines did. I knew that combination was dangerous, even with a tolerance to the methadone.

Anyways, there were warning signs I paid no heed to that week. I was waking up passed out on the floor in the bathroom literally having ripped stuff off the wall and pulling the shower glass away from the wall. It was probably around 2pm when I passed out in there and I didn’t come to until late that night (8-9pm-ish).

Another day that week, I had passed out on the car ride home from the clinic and woke up in the driveway. The person I was with told me we had been there 10 minutes and he tried shaking me with no response. This was an hour after taking both substances.

Anyways about a week in, weatherization was doing the windows in the apartments in the house I live in. After arriving back from the clinic at 11am (1 hour 15 mins after dosing both substances) I told the workers to knock when they were ready as they were finishing up in the apartment next to mine. Apparently around noon they knocked and I didn’t answer. They called the landlord who I knew pretty well and knew about my drug problem. Around 1230 (so 2 and a half hours after dosing) they opened the door to find me literally just inside the door passed out on the ground. I was completely unresponsive to any stimulus including a sternum rub and they weren’t even sure if I was breathing because my breaths were so shallow.

I woke up to a trooper and my landlord standing over me, having been narcaned. They asked me what I took. I told them I didn’t know. Honest to God, truly in that moment I didn’t know. I knew I took the methadone and phenibut but didn’t see how either of them could have resulted in my OD’ing (which is clearly what had happened given I was unresponsive until right after I was narcanned. I was so confused.

Shortly after the ambulance arrived and I was carted off to the ER. I was not in great shape, having been narcaned while being on a daily dose of 105mg of methadone. It was my second time ever being narcaned, but the first time I was opioid dependent. Obviously, it sucked.

On the way to the ER it finally occurred to me it had to have been the phenibut and I told the responders and later the doctors.

In the end, given both the methadone and phenibut we’re still being absorbed, methadone’s insanely long half life of 24-48 hours, and phenibut taking around 4 hours to fully take effect, it’s very likely if weatherization wasn’t doing windows in my apartment that day and hadn’t found me right around the time they did I would have very likely fully succumbed to the OD and died.

Given the shape the found me in, unresponsive and breathing so shallowly they literally couldn’t even tell that I was breathing… and the fact both substances were still being absorbed and weren’t at full strength it’s almost a certainty.

I just felt it was important to share the experience. I was well versed in drugs. I spent my 4 years at college learning everything I could about them. I knew how they all affected the brain and how to potentiate different substances. I thought I knew everything I would ever need to know. I thought I knew what was dangerous and what wasn’t (not that it truly ever stopped me from doing anything dumb).

Even with everything I knew about the substances and the danger of mixing CNS depressants, I truly didn't think mixing phenibut with my daily dose of methadone was dangerous. I found out the hard way, it’s deadly dangerous.

Hope someone sees this someday and maybe reconsiders mixing the 2 or doing it very carefully. Yes I know for the average person 105mg of methadone is a TON and would kill the average person. However as a maintenance dose, it’s truly not that big. I was only doing around 1.5-2g of phenibut with it, which isn’t that large of a recreational dose. In the end, the 2 together did exactly what opiates and benzos do mixed. They likely doubled the strength of each other leading to far more CNS depression than my body could handle and I almost payed for it with my life.

If weatherization didn’t happen to be doing my windows that day, I’d likely not be here to be writing this post! Please be careful mixing phenibut with larger doses of opiates…. Even if it’s the same dose you’ve taken everyday for over a year. That tolerance made zero difference in stopping it from causing an overdose in me!

It was just over 8 years ago from that happened, which gives me just over 8 years clean. I just finished tapering off the methadone as well.

Hope all of your 2026 goes well for you! Stay safe!
 
Bro, first off congratulations on your 8 years. I tip my hat to you sir while winking awkwardly.

I wish I could say I had that much time. Im always happy to hear someone has made it out.

Thank you for taking the time to share this. Im going to move it to our dedicated trip report section.
 
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