When I abused high doses of pregabalin (6 grams EOD) and cold turkeyed from that. I got a severe psychotic and suicidal depression with major anxiety. They put me on 30mg of olanzapine and 45 mg mirtazapine for 3 months. I was healed from the pregabalin withdrawal within 4 months.
However, I cant trip on psychedelics anymore. Its been over 6 months since I quit both olanzapine and mirtazaline and I still cant trip. I tried multiple tryptamines and LSD from legit sources, and no matter what dose, nothing happens.
I know both olanzapine and mirtazapine block 5ht2a receptors. But I would assume that my now they are out of my system and dont bind to any of these receptors anymore.
Did the use of these medications changed the expression and sensitivity of the 5ht2a receptor longterm or even permanent? Anyone has any knowledge on this or experience with this?
However, I cant trip on psychedelics anymore. Its been over 6 months since I quit both olanzapine and mirtazaline and I still cant trip. I tried multiple tryptamines and LSD from legit sources, and no matter what dose, nothing happens.
I know both olanzapine and mirtazapine block 5ht2a receptors. But I would assume that my now they are out of my system and dont bind to any of these receptors anymore.
Did the use of these medications changed the expression and sensitivity of the 5ht2a receptor longterm or even permanent? Anyone has any knowledge on this or experience with this?