Opioids Perc and Dilaudid Cross tolerance?

[starlett7]

If I've been taking dilaudids then switched to percocets, would I have any tolerance to the percs?

 

[LeLouche]

Yes. They are both active on the mu opiod receptor. You'll also have cross tolerance with most other opiates.

 

[eukaryote]

As above, yes indeed. You will be cross tolerant to all other drugs which bind to the same receptors , so essentially, anything binds to either the u-opiate or k-opiate receptors... which covers the vast majority of anything one would call an opioid.

A rough estimate of the equivalency of oral hydromorphone to oral oxycodone is double the milligram dosage. 10 hydromorphone should be replaced with 20 oxycodone.

This is just a rough estimate and obviously it should be titrated to optimal effectiveness in a safe manner.

 

[starlett7]

thankyou for the info!

 

[Tripman]

I'm closing this.

In the future a simple use of the search engine would have solved this query.

Or taking a walk through the OD directory.

Please utilize the resources you have before making a thread about it.

Closed.