Golden post mate, lots of good info. I forgot about the liver issues. Any idea whether if it's high doses that are bad for the liver or is it just bad all the way around? I'm worried as my 13 year old sister takes 100mgs for sleep and my dad has been on 900mgs a day for like a decade. I still think I'm going to try to get back on a lowish dose because it really is the only non addictive drug that can put me to sleep. My mother also mentioned that my sister's neurologist said there are studies show that it may be used to combat G.A.D. or even better it could help with my crippling social anxiety/agoraphobia. Fingers crossed...
I would believe no matter what dose you are on Seroquel is never good for you and is most likely the opposite aka bad for you.
Of course though, it goes without saying that the higher the dose the worse for you it will be and the more pressure it will be putting on your body (including the liver yes) and brain.
If you are going to use it then for the sakes of harm reduction start of low and work your way up until you find a dose which works for you.
I'm no Dr... But knowing that some Dr's prescribe Seroquel for sleep (Which is a big no no especially if you haven't tried medications intended for sleep & are safer or less toxic first. Something that seems all too common these days from reading forums such as Bluelight, etc) makes me question if I am just as clever if not more clever than some Drs. lol.
I have never taken a dose bigger than 50mg.
I find 30mg to be sedating enough. I remember the first time i took it, i took 30mg and i was almost glued/paralyzed to my bed.
I remember semi-getting up once in the night as i needed to pee (drank more than usual before bed) but was so bloody sedated I had to hold it until the effects were reduced a bit. It was only then I could actually stand up and go to the bathroom.
Even when i managed to do this however, the body load and sedation i felt from the Seroquel was extremely powerful.
I remember the morning after using it for the first time one of the most pervasive thoughts going on in my mind at the time was questioning how my friend (the one who gave me them to try) and many others take 100mg or more of this shit on a daily basis ! - Many of whom do this when it's first prescribed with no tolerance to the drug as well 0_0
I was originally going to listen to my friend & the internet when they suggested I take 100mg or at least 50mg minimum my first time. But i'm so glad i didn't listen. If i took the 100mg my guess is that I would have literally slept for maybe close to 40 hours.
The 30mg already made me sleep a good 12 hours and had me waking up kinda groggy. Tbh if I didn't use it on a weekend like I did and used it during the week when i have work &/or classes idk how i would force myself to get up lol after taking Seroquel the night prior.
Or well I don't take it at all and only took it a few times so who knows (people who take Seroquel regularly?) - Maybe when taken more often, Seroquel tolerance kicks in and the super strong sedating effects become more bearable and not so intense.
BUT ^ tolerance to Seroquel is not exactly something you want as it can be addictive and have some pretty nasty withdrawals. To withdrawal you would have to taper off the medication. Something which may sound easy but i know a few people trying to quit it and are tapering. They are finding it extremely hard.
One of my good friends has been taking it for almost 2 years now and over the last 6 months has trying to be tapering off Seroquel to the point where his dose is so low he can stop.
He's told me that the withdrawals from the medication make him feel like utter shit. He can barley sleep and when he does the sleep isn't of good quality. He is also having nightmares more often, thrashes around in bed.
From this lack of sleep he feels fatigued every day, irritable and not in the greatest state of mind.
Sometimes he caves because of this or other reasons, can't take it and takes a larger dose that will stop his Seroquel w/d but kind of ruin his taper regime which he has come so far with until he caved.
Not to mention some more worrying side effects or withdrawal effects he's told me that he's getting and aren't uncommon amongst others weaning of Seroquel... More physical effects like akathisia, restless legs, tardive dyskenia, liver issues and other side effects such as a higher risk of parkinsons desiese when older especially from meds playing around with the brain's dopamine reuptake.
Anyways, yeah definitely try it if you want. But if you can try and ask your Dr. about trying some safer.
Like i mentioned earlier there are much, much safer and less toxic options available in terms of medications for insomnia.
My favourites include Remeron (Mirtazapine), Trazadone, St. Johns Wort, Valerian, marijuana (For some. I know for some it can keep you awake. Strain can also play an important role in it's success for insomnia treatment) and if they don't work then Benzodiazepines...
Benzos i don't believe are good for you either and would advise against using them unless you really need it and have tried other, safer/less toxic/less side effect meds first (aka the other ones in the list above). In fact benzos aren't good for you at all and i find they are horrible when it comes to the side effects they have on ones cognitive function which i guess can be reduced by taking a small dose vs large dose - but this doesn't make the cognitive side effect completely go away. Just reduced.
However, even though I believe benzos are bad for you & don't think you should take them unless really necessary I personally still believe they do less damage to ones body when compared Seroquel. And this is the only reason as to why i listed it ^
My favourite sleep aid would be either Remeron (Mirtazapine) or a heavy indica weed strain with not much weed tolerance in me (With high tolerance I find weed barley works. However after coming back from a tolerance break from weed when having a low tolerance I find it is then that it works like a charm for helping one get to sleep and stay asleep.).
I would recommend them^ and they are my favourites as they...
1) Get me to sleep and keep me asleep. Something that keeps me asleep is something I need as I have more of a problem with that than getting to sleep.
2) Seem, feel safe, least toxic and have low side effect profiles (both short term and long term) when compared to other medications used for insomnia.
3) Don't make me nearly as groggy and/or out of it in the morning and throughout the day when compared to other medications used for insomnia. After waking from using these medications before falling asleep I feel my cognitive functions haven't been negatively effected all too much - Especially when compared to other medications like Seroquel or Olanzapine aka Zyprexa (an psychotic which shouldn't have been prescribed to me in the past for sleep but was anyways -_-. A year later after being prescribed it I've still got the box of pills, untouched lol.)
I mean theres nothing better than a drug free, good quality sleep. But for many of us that is hard to come by and I feel my favourite medications for insomnia that help me come closest to sleeping a drug free, good quality sleep would be Mirtazapine &/or Cannabis.
4) They seem to have the least addictive qualities... Sure, blasting some opiates every night or taking a handful of benzos would make me sleep and keep me asleep great but at the same time it would be a terrible idea as the addiction formed is not worth the good sleep. This applies to Seroquel, Olanzapine and even Trazadone. However, i find when i've used Mirtazapine or Cannabis a bit too often, more than I've liked or too much it's easier vs the other meds i've mentioned to stop with side effects/withdrawal symptoms no where near as bad as the other insomnia medications mentioned in my post.
Hopefully this helps!