I have to say I fucking loved Masteron (enanthate). DHT based. Strength, vitality, drive to train and fuck!
Also serves well to keep E2 in check when using other aromatizing steroids. (not as good as using Anastrozole etc though)
Test 2-300 + mast 3-400mg per week will have you feeling amazeballs.
You can run it alone even but I stick with test as a base for anything, just my preference.
Want to look good, feel good and actually aid your body while at it? Pharma HGH is where it is at. $ tho
Just because masteron doesn't aromatise, doesn't mean it acts as an aromatase inhibitor..
Masteron by Peter Van Mol:
I've read this stupidity in so many threads on here, and literally every other board, book and article, that I just decided to make this into a new thread. But apparently no one in the whole AAS game understand the difference between androgen mediated repression of estrogenic actions and actual anti-estrogenic actions.
SERMS, are partial agonists and partial antagonists at the ER. Where they are antagonistic (like all of them are in the breast), they can be considered anti-estriogens. Aromatase inhibitors are anti-estrogens.
Dihydrotestosterone and ONLY dihydrotestosterone, as an androgen, has very mild anti-aromatase activity and could be considered a very mild anti-estrogen.
THIS DOES NOT, NEVER DID, AND NEVER WILL MEAN THAT EVERY 5-ALPHA-REDUCED HORMONE (or DHT derivative as some like to call it) HAS ANTI-AROMATASE ACTION.
Androgens of all sorts, including actual testosterone, have been used in the clinical treatment of breast cancer, because androgen receptor binding in the breast, outweighing estrogen receptor activation, will counteract the estrogen-induced proliferation of breast cells. This is not an anti-estrogenic action, this is merely a function of androgens in the breast to counteract breast growth. This applies to :
- Mesterolone. Basically 1-methyl DHT, but the A-ring modification would interefere with aromatase binding. Meaning if DHT is a weak anti-aromatase drug, then the activity mesterolone might still have would require in excess of 500mg per day to have any direct anti-aromatase effect worth having.
If you are using Proviron specifically as an anti-estrogen, you are wasting your money. It's effect in this regard is no different than any other potent androgen.
-Drostanolone, the 2-methyl group isn't just an A-ring modification that prevents or limits aromatase binding, it structurally protects the 3-keto group from being reduced, which is a requirement for aromatase function.
Drostanolone is absolutely NOT an aromatase blocker. This is just some label given to it by people who saw it was predominantly used in treatment for breast cancer (which it was quite good at, because despite its weak nature, it is a very pure androgen, with little or no interaction outside of the AR) and the fact that it was structurally related to DHT.
-Epistane, similar to drostanolone, the non17AA version Epitiostanol was principally used to treat breast cancer. There is no evidence or suggestion that points to either structure having the least bit of affinity for aromatase, let alone being a functionally active inhibitor in doses used.
- Stanozolol, is MOST DEFINITELY NOT an anti-estrogen. On the contrary. The study mentioned below shows that Stanozolol can actually induce partial estrogenic sexual maturation in ovariectomized female rats. It would actually be an extremey weak estrogen, rather than an anti-estrogen.
Whitney AC, Clark AS. Effects of acute stanozolol treatment on puberty in female rats. Biol Reprod 2001 May;64(5):1460-5.
So please, do not confuse these things. known AI's like letrozole, anastrozole and exemestane are anti-estrogens. SERMs are conditional anti-estrogens. DHT, as a very, very mild AI, could potentially be termed modestly anti-estrogenic. Pretty much all other androgens we use
ARE NOT ANTI-ESTROGENIC. Their effect in counteracting estrogen is purely based on their activity at the AR, and the effect is always going to be greater for more potent androgens.
If there is no evidence of anti-estrogenic action, please don't go around saying it's anti-estrogenic. Any increase in A:E ratio by the addition of a non-aromatizing, non-estrogenic androgen will in fact have some apparent estrogen countering effect, simply because you are increasing the ratio of androgens to estrogens.
Big Cat..