I am thinking about trying my first dose of 2C-N tomorrow. I found myself 350mg of it. I'm not expecting anything ground breaking but I want to do a workup of an incredibly rare substance and add to the report literature. I don't know of any reports at the 60mg level. Most reports are at 100mg or more, and they report heavy, sometimes concerning bodyload, and positive effects ranging from good feels to wild visuals, and a short duration. My tentative plan is the following trials:
60mg oral
130mg oral
65mg rectal
95mg rectal
This will allow me to assess whether it is about twice as potent rectally as orally. I would assume it is since all the other 2C-Xs are. And hopefully it would also reduce the bodyload. Then I would get a chance to get 4 doses out of it, and also report on a lower dose than I know of any reports of. The only potential concern I have is the 95mg rectal dose, that should be equivalent roughly to 190mg oral which is substantially higher than any other report I've read about, and some reports talk about frightening physical side effects. I guess I'll just judge whether that is a good idea as I go. The 130mg oral dose seems to be right around the "typical" dosage reported (morninggloryseed's +4 experience where he relived childhood memories and had an incredible experience, and where he also puked out of both ends and experienced terrible stomach pain, was at about that level).
PIHKAL reports don't seem to suggest anything particularly noteworthy, but I find PIHKAL reports to almost always leave something to be desired.