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Misc Parnate

O

obsoletebg

Greenlighter
Joined
Jun 13, 2013
Messages
25
Is anyone here on parnate? My doc just started me on 20mg a day for atypical anergic depression, hypersomnia, and anhedonia. I am going to post my results on here. Right now it has only been 2 days. Haven't felt much except for an increased feeling of wakefullness a little bit. I am really counting on this one because SSRI and SNRI have not worked for me too well and my depression is getting to the point where I cannot even get myself out of bed.
 
I'm sorry you are having a problem with depression. I have not personally ever taken "parnate", but I still wanted to tell you that you are definitely not alone in feeling the way you do. Some peoples lives can be much harder than others, for many reasons, but trying to stay positive(even if it's just a little bit), and keeping yourself busy are usually good ways to help yourself get out of that "slump" that you can feel like your in.
I've had my share of depression because I became disabled in 2010 at the age of 22 and every day since I live in my bed. Just like you, I can't get myself out of bed. I have to spend at least 23hrs a day in bed, I have no choice in the matter. And even though I'm stuck in bed for different reasons than you, it still makes me feel depressed often because I was a bigtime athlete my whole life. Now I need a wheelchair to go to my drs visits.
Basically, life can be VERY hard... and sometimes this can make you feel depressed, so I'm very glad you decided to come on BL to get help/advice. I would even recommend that anytime your feelin' down you come onto BL and just talk with people, because there are a lot of people here who care.
Good luck to ya.
 
jamesBrown said:
I'm sorry you are having a problem with depression. I have not personally ever taken "parnate", but I still wanted to tell you that you are definitely not alone in feeling the way you do. Some peoples lives can be much harder than others, for many reasons, but trying to stay positive(even if it's just a little bit), and keeping yourself busy are usually good ways to help yourself get out of that "slump" that you can feel like your in.
I've had my share of depression because I became disabled in 2010 at the age of 22 and every day since I live in my bed. Just like you, I can't get myself out of bed. I have to spend at least 23hrs a day in bed, I have no choice in the matter. And even though I'm stuck in bed for different reasons than you, it still makes me feel depressed often because I was a bigtime athlete my whole life. Now I need a wheelchair to go to my drs visits.
Basically, life can be VERY hard... and sometimes this can make you feel depressed, so I'm very glad you decided to come on BL to get help/advice. I would even recommend that anytime your feelin' down you come onto BL and just talk with people, because there are a lot of people here who care.
Good luck to ya.
Click to expand...


Good luck to you also. I really feel for you regarding being bedbound. The mornings I wake up are the hardest for me. Sometimes I will break down when I wake up in the morning because I feel so depressed and hopeless. I currently am on leave of absence for 2 weeks from work to try to get to the core of the problem. Since I didn't respond to SSRI's, my doctor thinks my brain is not producing enough dopamine and is the reason why I have no energy and bad depression. He stated the parnate will help raise my dopamine levels which should help with me getting out of bed and not sleeping so much.

Wish me luck guys.
 
Sorry to hear that times have been rough. Hopefully it helps. I'm on Parnate- same sort of deal, went through a few medicines. Although my depression was a bit different, I can say it worked well with anhedonia and morning depression. (At 70 mg, but again, different kind of depression.) Try to take it right when you get up and do some small things in the morning. Really helped with pushing through and connecting to a few behaviors in the day. I had no issues with food, although I monitored my BP meticulously because of how I sort of am. Avoided the usual large amounts of aged cheese and my friend's homebrew beer. Everyone is different, though, and it appears there is a subset of people with a real sensitivity to the Tyramine reaction. Other side effects may vary. Saying it isn't a clean drug might be a bit of an understatement.

It might be a good idea to spend the two weeks doing normal things and getting back to a somewhat better schedule. Just kind of living and doing things without focusing on depression and all that. I've seen some people try to get to the root of depression or whatever problem at their lowest point, and to be honest, my experience is that it is too easy to get caught up in identifying problems or forming plans rather than going through the day and experiencing life. It can be tempting to want a target or definite explanation, but if that search isn't helpful, maybe it would be best to hold off while you feel your worst and spend time on living a regular day. Whatever works. On the other hand, maybe it is a more definite thing with you and there are clear issues to be sorted out. I can't say.

Again, hopefully you feel better with the Parnate. Depression is tough. Best of luck.
 
^^^see what I mean obsoletegb?..... there most definitely ARE people here in the BL community who care. You are welcome to PM me if you like if you feel like talking to someone . Plus... I'm cheap!.... I don't charge $200/hr, in fact it's free! That was a bad joke, but I truly am serious about you PM'ing me if you want to.
Best of Luck!
 
obsoletebg - I have been a Bluelight lurker for about 7-8 years and finally registered in order to reply to your thread. When I was first prescribed Parnate I was extremely reluctant and fearful to take it because of how MAOI's are portrayed and I tried doing some research on the web but could find absolutely nothing - which is why I wanted to share my experiences with you. Finally I sucked it up and finally started taking it because I suffer from extremely treatment resistant bipolar 2 disorder and atypical anergic depression. I can undoubtedly say after over a decade of violent drug reactions/interactions and much suffering Parnate literally saved my life. Not only have I been able to become a productive member of society, I also lost nearly 70 lbs of "bloat" gained due to atypical antipsychotics like Seroquel. Definitely a good option if all else has failed.

Parnate in irreversible inhibitor of MAO-A and MAO-B so it will definitely help you out in the dopamine, serotonin, phenylthylamine, etc....department
 
That is good to hear skeletor. I was reluctant too because I was scared of the "cheese effect", but so far I haven't experienced anything bad as side effects go. I'm on a pretty bland diet, mostly chicken, corn bread, sandwiches, ice cream. Can't eat pizza , sausage/dried meats, soy or Chinese food anymore, but its not too bad. It turned out that Parnate is probably the easiest antidepressant I've taken with regards to side effects. As long as my diet is good, I rarely feel any side effects. I always thought MAOI would have the most side effects, but from what my body is telling me is that it is one of the least harshest antidepressants I've ever have taken with regards to side effects.

It only been a week now, at 30mg a day. So far I feel a little "lift" in my mood. Depression doesn't bother me as much. Seem more resilient. For a few days I did experience tiredness and sluggishness and a feeling of wanting to lay down and sleep on day 3 and 4. But the tiredness started to lift after day 5-6. Doctor told me to be patient because he said MAOI's have a habit of taking around 2-3 weeks and their effects tend to creep up slowly. One great thing is the feeling of hopelessness when I wake up in the morning is not there that much anymore. And I am able to get up in the morning without it becoming a big mental battle. It seems my mind doesn't "think" about it that much anymore.

I go back to work on august 4th. so that gives me another week for the parnate to settle in. Its not a miracle, and I do still have symptoms but I feel the "relieving" effect on my mood which has probably blunted around 60% of it. It will be interesting to see how I function at work next week.
 
obsoletebg said:
That is good to hear skeletor. I was reluctant too because I was scared of the "cheese effect", but so far I haven't experienced anything bad as side effects go. I'm on a pretty bland diet, mostly chicken, corn bread, sandwiches, ice cream. Can't eat pizza , sausage/dried meats, soy or Chinese food anymore, but its not too bad. It turned out that Parnate is probably the easiest antidepressant I've taken with regards to side effects. As long as my diet is good, I rarely feel any side effects. I always thought MAOI would have the most side effects, but from what my body is telling me is that it is one of the least harshest antidepressants I've ever have taken with regards to side effects.

It only been a week now, at 30mg a day. So far I feel a little "lift" in my mood. Depression doesn't bother me as much. Seem more resilient. For a few days I did experience tiredness and sluggishness and a feeling of wanting to lay down and sleep on day 3 and 4. But the tiredness started to lift after day 5-6. Doctor told me to be patient because he said MAOI's have a habit of taking around 2-3 weeks and their effects tend to creep up slowly. One great thing is the feeling of hopelessness when I wake up in the morning is not there that much anymore. And I am able to get up in the morning without it becoming a big mental battle. It seems my mind doesn't "think" about it that much anymore.

I go back to work on august 4th. so that gives me another week for the parnate to settle in. Its not a miracle, and I do still have symptoms but I feel the "relieving" effect on my mood which has probably blunted around 60% of it. It will be interesting to see how I function at work next week.
Click to expand...

I can completely relate to you as far as the uphill battle to get out of bed. I used to sleep in until 1-2pm most days because I just did not have the motivation or drive to do anything. These days I wake up basically when the sun comes up, jump out of bed, and get to my day feeling pretty good most of the time. Parnate literally saved my life. I have been on 30mg a day for about a year and a half now and I am able to eat pizza, cured meats/sausage/cheese/etc....without any problems (these are some of my favorite foods). The worst side effects I have gotten from the Parnate have been the result of forgetting to take my dosage for a day or two and then I start to get light headed, almost as if my head is a balloon floating away, but that is about it. Definitely has boosted my energy/metabolism, sex drive, concentration, mental stamina. It really is a shame that this drug is used as a "last line of defense" type drug for very treatment resistant cases of atypical anergic depression.

My depressive phases are managed very well by the parnate (it stabilizes everything to a pretty neutral point) however there are times where I begin to get hypomanic and I use .5-1.0 mg Xanax to settle down, as well as removing myself from the stimulus.
 
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