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  • BDD Moderators: Keif’ Richards

Oxycontin dosage

N

nyancloud

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Joined
Jul 1, 2013
Messages
23
Just tried oxycontin OC for the first time, I took 7,5, an hour later 2.5, then half an hour later another 5 and 5mg. That would be 20mg in total.
I really don't feel the effects of it, should I take more? I just feel a little chilled out and that's all. No euphoria or anything like that. I mean, what the hell, I saw people writing 5-10mg would get you high, is something wrong with me?

A friend of mine who took 5mg is experience some effects and says he is definitely feeling something good.

Is it possible that I need more? I'm not heavy or anything like that. I'm really disappointed with oxy so far..
 
Some people are like that they seem to need ridiculously high amounts of oxy to feel it but oxy in general isn't really a crazy high IT'S pretty subtle I mean people only chase the high because its something they can function in, makes then happy, no one can tell they are in a drug, its a good painkiller, and because once you get an addiction its so dam physical that many people just cannot stop doing it.
If your looking for a good high I reccomed 30-40mgs and its really up to you if you want to keep chasing it after that I mean I know you will do what you do if you want to get high. When I was a kid we used to snort 80s and would puke almost every time or try our best not to puke and that was like too much oxy for us since we were only newbs.
Nowadays if someone gave me an oxycodone I wouldn't think twice about popping 200+mgs. Because mY tolerance has shot up so much after a decade of opiate abuse
 
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You spread it out a fair bit, and opiates are fairly subtle compared to some drugs, often a bit of an acquired taste. 15mg at once (along with a low dose antihistamine to prevent nausea) is what I'd suggest to new user.
 
Oxy ER(oc/op) sucks orally.

Did you know that Purdue itself did a study(prior to FDA approval) and they admit that 10mg OC (orally) was no better than a placebo for analgesia?

Think about that; 10mg oxycodone ER, no better than placebo. Now, clearly for adults, the "recreational" dose is higher than the analgesic dose. The analgesic dose is 20mg; therefore, MOST PEOPLE(you) will need more than 20mg OC for any recreational effects, even if opioid naive.

In your case, spreading the dose didn't help. Next time, take 40mg at once and you'll get what your looking for. I would advise taking an antihistamine, however, as it will reduce the effects of itching/nasuea, and if it's a first-generation antihistamine(diphenhydramine(Benadryl), doxlyamine,(NyQuil/Unisom classic), diphenhydranate,(Dramamine), chlorphineramine, etc) it will enhance the effects, though any AH will do.

Also, when you say "OC" are you referring to the new(abuse proof) OP's, or by chance do you actually have the classic OC's???

That is all!!!
 
Lorne??? said:
Oxy ER(oc/op) sucks orally.

Did you know that Purdue itself did a study(prior to FDA approval) and they admit that 10mg OC (orally) was no better than a placebo for analgesia?

Think about that; 10mg oxycodone ER, no better than placebo. Now, clearly for adults, the "recreational" dose is higher than the analgesic dose. The analgesic dose is 20mg; therefore, MOST PEOPLE(you) will need more than 20mg OC for any recreational effects, even if opioid naive.

In your case, spreading the dose didn't help. Next time, take 40mg at once and you'll get what your looking for. I would advise taking an antihistamine, however, as it will reduce the effects of itching/nasuea, and if it's a first-generation antihistamine(diphenhydramine(Benadryl), doxlyamine,(NyQuil/Unisom classic), diphenhydranate,(Dramamine), chlorphineramine, etc) it will enhance the effects, though any AH will do.

Also, when you say "OC" are you referring to the new(abuse proof) OP's, or by chance do you actually have the classic OC's???

That is all!!!
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40 is way too much for someone without a tolerance, he'll be throwing up and passing out.

15 - 20 IR dosed at once is plenty for most people starting out. If that doesn't hit the spot, he can top it up by snorting (if he doesn't have OP's) or just ride it out and increase the dose by 5 - 10mg next time.
 
^^^ he says he has oxy ER, NOT ir, so that doesn't apply. And he already took 20mg ER and got no effect.

Believe me, 40mg ER oxycodone is just fine, especially with an antihistamine. If he had IR oxycodone it would be a different story.

He says he has OC, but I doubt it. Probably OP, or one of the generics that gels up anyway.

And I'm serious about 10mg OC being no more effective than a placebo. Go check for yourself, at drugs.com.

Also, Cmax of oral oxycodone is less than half of the Cmax of oral IR oxycodone, so the peak effect will still be less than the peak of 20mg IR.
Trust me, he'll be fine.
 
Guess it comes down to what he actually has, if it's OP's then yeah 40 makes more sense.
 
Lorne??? said:
Oxy ER(oc/op) sucks orally.

Did you know that Purdue itself did a study(prior to FDA approval) and they admit that 10mg OC (orally) was no better than a placebo for analgesia?

Think about that; 10mg oxycodone ER, no better than placebo. Now, clearly for adults, the "recreational" dose is higher than the analgesic dose. The analgesic dose is 20mg; therefore, MOST PEOPLE(you) will need more than 20mg OC for any recreational effects, even if opioid naive.

In your case, spreading the dose didn't help. Next time, take 40mg at once and you'll get what your looking for. I would advise taking an antihistamine, however, as it will reduce the effects of itching/nasuea, and if it's a first-generation antihistamine(diphenhydramine(Benadryl), doxlyamine,(NyQuil/Unisom classic), diphenhydranate,(Dramamine), chlorphineramine, etc) it will enhance the effects, though any AH will do.

Also, when you say "OC" are you referring to the new(abuse proof) OP's, or by chance do you actually have the classic OC's???

That is all!!!
Click to expand...

Do you have any idea how the time release mechanism works on the OC/CR's? I think I read 50% is released immediately but do you have any definitive info on this?
 
An OC 40 crushed up and snorted isn't going to kill a person even without a tolerance now a oxy 80 or 160 crushed up that's another story.
He said he felt nothing so yes 40 is fine..
 
With extended-release oxycodone, I would recommend, if taken without defeating the time-release mechanism, no more than 20 mg the next time, regardless of the first experience. If the time release is defeated, I wouldn't go above 10 mg the next time, again regardless of the first experience. Opiates, like oxycodone, have different effects on different individuals, especially for those who have never before taken opiates. For some, the first opiate experience is thought to be the greatest thing in the world, for others quite underwhelming and leaving the individual asking what the hype was about. But, the opiate experience is one of a lot of euphoria, but particular and subtle euphoria, that for some does not really stand out the first time, the first few times, or sometimes really ever. Just because the initial experience is underwhelming, does not at all indicate the dose needs to be increased - this is rather impatient, and can lead to trouble. A great opiate experience does not always require a couple tries, but sometimes it does. The euphoria is extraordinary and powerfully lifting; it is just subtle, and can be easily ignored or tainted by certain unfit settings. The best setting to take an opiate for the first few times, at least, is really the user's home, usually best able to be appreciated while relaxing and lazing about, or upon retiring to one's bedroom in the evening when rest and relaxation are preceded for a couple hours before sleep. The user should not really expect anything, and just let the warmth envelop him, and the waves of euphoria roll over him, letting his mind go into fantastical daydreams and his body fall limp and still. That is how to enjoy the opiate. To sum it up: No expectations, a bed or comfortable couch, a place where the user could sleep if desired, minimal activity, rest and relaxation, no outside bothers, familiar environment, and there you go.
 
Numb19 said:
Do you have any idea how the time release mechanism works on the OC/CR's? I think I read 50% is released immediately but do you have any definitive info on this?
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The way it works with most CR opioids is that 30-40% is released initially, and the rest released gradually over the course of several hours. IIRC, with OC specifically, it is released in 3 stages, that has 1/3rd released each time.

But with oxy the Cmax is actually better short-term, because the half-life remains short. However with morphine CR, the half-life is actually extended, in some cases to 12 hours. This is why achieving steady-state takes longer with CR morphine, and can also lead to proportionally larger peak plasma.also keep in mind that the BA of oral oxycodone is highly variable, ranging anywhere from 40-90%, which contributes to the vastly different effects felt by people. But either way, 15mg IR morphine/oxycodone yields a higher Cmax than 30mg ER morphine/oxycodone. And 5mg IV will yield higher Cmax than 30mg ER!!!
(Well with oxy it could take 7.5)
 
he said oxycontin(continuous release) even an 80 wouldn't kill even an opiate naive person because it is designed to work for 12 hours. Thats less than 7mg/hr. now it does instantly release up to 15mg but taking that into consideration with the extended release thats less than 5.5mg/hr

basically oxycontin sucks unless you are already taking oxycodone then its a SMALL add on to the ir oxy
 
nyancloud said:
Is it possible that I need more?
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Well...

I really don't feel the effects of it, should I take more? I just feel a little chilled out and that's all. No euphoria or anything like that.
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Absolutely. Oxycodone is a mu-opioid agonist of comparable strength to morphine and heroin (though not as euphoric for most, or nearly as sedative). "A little chilled out" is clearly a case of dosing too low - oxycodone is strong.

Some people also metabolize it at different rates due to differences in their enzymes, and some people are more sensitive than others. You also spread your doses out a bit, and oxycodone is quite short-acting. In any case, while 20mg should be noticeable as a first time for most people, it's not a particularly large one. Especially if you didn't chew it - then it's a very normal analgesic dose (which the doctor would start you off with - 10-20mg), and most people would not feel very much, apart from reduced pain if they were previously in pain.

I'm 6'4" and am not generally sensitive to opioids, but for my first time taking oxy (or any opioid stronger than tramadol, in fact) I ate 40mg powdered up. That was a pretty damn strong dose, and 30mg would have probably done the trick as well, but it wasn't unpleasant.

Completely crush up 30mg and eat it at once, and see what happens.
 
Jesus Christ, I think we need to give the OP a little time to learn the opiate before moving him up to such relatively large doses for someone with no prior experience with opiates. It is very irresponsible, unsound, and this advice to up the dose seems to come with a lot of falsehoods in the reasoning to do so. Opiates are, though powerful, subtle euphoriants which are certainly an acquired taste for many, many people. I consider someone like me, who loved his first experience with an opiate (5 mg oxycodone instant-release), the different kind of person, - the next time I did it, I came to the very appropriate conclusion that 10 mg would be the best dose with respect to that opiate when I was, too, opiate-naïve. I only increased much later in my 'here and there' history of opioid use, save for tramadol, an can now tolerate and enjoy a dose of 30 mg of oxycodone as a strong dose, still never having gone above 40 mg oxycodone. Really, the OP needs to try oxycodone, at a dose of around 10 mg IR or 20 mg ER, and not much more to get the idea of what an opiate is; the first time, and first few times, are often flukes for users who later come to find they really enjoy them. But, let me also say that opiates are EXTREMELY ADDICTIVE, and in a particularly distinct and tricky way - be careful.
 
Alex000 said:
Jesus Christ, I think we need to give the OP a little time to learn the opiate before moving him up to such relatively large doses for someone with no prior experience with opiates. It is very irresponsible, unsound, and this advice to up the dose seems to come with a lot of falsehoods in the reasoning to do so. Opiates are, though powerful, subtle euphoriants which are certainly an acquired taste for many, many people. I consider someone like me, who loved his first experience with an opiate (5 mg oxycodone instant-release), the different kind of person, - the next time I did it, I came to the very appropriate conclusion that 10 mg would be the best dose with respect to that opiate when I was, too, opiate-naïve. I only increased much later in my 'here and there' history of opioid use, save for tramadol, an can now tolerate and enjoy a dose of 30 mg of oxycodone as a strong dose, still never having gone above 40 mg oxycodone. Really, the OP needs to try oxycodone, at a dose of around 10 mg IR or 20 mg ER, and not much more to get the idea of what an opiate is; the first time, and first few times, are often flukes for users who later come to find they really enjoy them. But, let me also say that opiates are EXTREMELY ADDICTIVE, and in a particularly distinct and tricky way - be careful.
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OP said:
Just tried oxycontin OC for the first time, I took 7,5, an hour later 2.5, then half an hour later another 5 and 5mg. That would be 20mg in total.
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If you'd have read his post you would notice he clearly says he took 20mg, and felt "a little chilled out and that's it." If 20mg is a threshold/mild dose, then adding another 10mg is unlikely to result in an unpleasant experience.
 
Psychonauticunt said:
If you'd have read his post you would notice he clearly says he took 20mg, and felt "a little chilled out and that's it." If 20mg is a threshold/mild dose, then adding another 10mg is unlikely to result in an unpleasant experience.
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It would be terribly unlikely that 20 mg, even if extended-release, would be anyone's threshold dose as you say. If you read my post, I think he needs to learn to appreciate a dose more appropriate for someone with no opioid tolerance, before taking this fast and loose approach of just increasing, even doubling by some suggestions! If nothing dangerous happens at that dose consumed in one sitting, it will at least jack his tolerance up nice and high and start off someone's opioid career with a real disadvantage. And, in reading his post, part of the important part that I read was that he dosed it in a way so as to space out many smaller doses to come to the larger one of 20 mg, even if extended-release, for that kind of dosing does dull opioid euphoria, which I will again iterate is a subtle euphoria, however powerful and lovely.
 
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