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Opioids Oxycodone hydrochloride

Oh, I forgot to mention that the autoinjectors also had a sort of wax at the bottom. You put a yellow cross on the forehead of someone who has been given a yellow top and guess what? A red cross for the 10mg morphine autoinjectors. AAIs (adrenaline autoinjectors) I've never seen.

Protocol was that you use the autoinjector in the muscle just above a limb injury so it doesn't just bleed out & because morphine also acts on peripheral MOR receptors. For a body injury just into any handy bit of muscle. Head injuries, no morphine. I have NO idea if someone with a head injury would or would not be given a yellow top. I'm GLAD I never had to find that one out.

Now COULD a seriously injured casualty be given more than one red top? Yes. Each pack contained two. I only know of a single example and yep, a second red cross went onto their forehead.

But just to be clear, my information is 23 years out of date. Protocols change. I think ketamine was trialled for a bit then fentanyl lozenges. But I think they have gone back to M. It works, it's understood, it's cheap.

Patrols were each issued a morphine coffin and I suspect whatever analgesic is actually in them, the nick-name won't change. Squaddie humour.
 
FYI that pre-tretment I couldn't remember the name of. Well I checked - 2-PAM (Pralidoxime iodide). I GUESS the iodide was also designed so if a radiological hazard was encountered, it would reduce the amount of 131I absorbed. But to be clear - that IS just my guess.

It turned out to be a likely cause of what is (or was) called 'Gulf War sydrome'.
 
alright you gunna want micro filters since its a pill. Looking at your tolerance I would say 2 mgs should be good.

Oh yea what brand of pill or what are the markings on it?? I hear alot are simply not IV'able anymore -- but I am way behind the scene

Make sure you use sterile water! I recently learned that tapwater coulda got me dead. (Well I had a reverse osmosis 0 ppm system at the time, maybe that saved me..)

mix the powdered pills with a couple ml of water -- filter thoroughly until you have a clear solution.

do what ya gotta

this is not medical or any kind of advice

ps dont misquote me like that I dont want ppl to think im using again
 
Was in the army in SF unit.
All of the “medics” had a bag full of whatever you’ve ever wanted
Injectable benzos , ketamine , morphine , fentanyl can’t even remember what else but we had it all , if you were slightly injured let’s say you strain a muscle or an ankle or whatever you got a morphine injection IM very easily. If you happen to be injured to the field you got a cocktail of morphine or fentanyl along with ketamine , we learned that in such a situations say you’ll lose an arm and in front of you your best friend have it’s brains blown out , you need an opioid along with ketamine , analgesia isn’t enough in such situations you must be out of it completely.
 
Dextro .45 said:
Well….just like any XR formulation…..you can pulverize the beads into fine powder, it’s now IR

BIPHENTIN 80mg XR beads (Methylphenidate) …..40% is IR remeaining 60% released 4-6 h later…..for bi phasic release, hence the name Biphentin

I pulverize my XR caspules so it’s IR Ritalin (Methylphenidate)…..essential in my oral cocktail

Methadone 100-125mg (160 tablets monthly)
Ritalin (Methylphenidate) 50-70mg IR
Avizafone (Pro-Diazepam) IM injection 80mg = Valium 40mg
Pregabalin 300mg
Ethanol & cigarettes

I’ve been on this daily for 20+ years so I’m extremely tolerant ……the dopaminergic stimulant is ABSOLUTELY essential. A staple. Period. Enhancing the analgesic properties of the opioid, reducing any sedation and improving cognitive functioning, increased vigilance, potent mood-boosting properties

Very euphoric & pleasurable…..but when ACTUALLY needed for chronic pain…..Fck, is like drinking water and eating……without it, I’d be barely alive . I’m 6’ male 240lbs tolerant to all substances so my doses are very manageable and low ish for ME ……a lethal dose for many others

Brompton Cocktail 🍸…..can’t be beaten even a proper Speedball


Pharmaceutical grade Diacetylmorphine (Heroin) and pure Cocaine HCL pharma grade……Amytal a proper barbiturate……..fuuuuuuuuuck, your melting into heavens warm blanket of security & comfort

1850 in Royal Brompton Hospital in England ….reserved for end of life suffering usually

An oral Brompton Cocktail 🍸 is my daily drink…..seriously
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God i wish I could get Focalin prescribed again I really love those. Probably the most ego enhancing prescription stim for me and extremely euphoric when you abuse it. It has a terrible crash which is what led me too abuse it. Id pop 2 or 3 40 mg xrs and my pupils would take up my whole eye ball lol. Then it made me crazy horny and I started skipping school. Way more recreational than Adderall in my opinion Id rather socialize on it then hyper focus on something like Adderall. It was fun mixing liquor and benzos with it too. Really rolly feeling for me with the phenidates.
 
fuckabout89 said:
God i wish I could get Focalin prescribed again I really love those. Probably the most ego enhancing prescription stim for me and extremely euphoric when you abuse it. It has a terrible crash which is what led me too abuse it. Id pop 2 or 3 40 mg xrs and my pupils would take up my whole eye ball lol. Then it made me crazy horny and I started skipping school. Way more recreational than Adderall in my opinion Id rather socialize on it then hyper focus on something like Adderall. It was fun mixing liquor and benzos with it too. Really rolly feeling for me with the phenidates.
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Ritalin (Methylphenidate) is VERY euphoric & pleasurable……nearly identical to Cocaine, both compete for the same binding receptors at the monoamine transporter DAT/NET (Cocaine DAT/SERT/NET)

Taking Ethanol with Ritalin increases d-threo-Methylphenidate (Focalin) by 40% SIGNIFICANTLY enhancing euphoric properties in all study participants. Also produces Levo-Ethylphenidate (inactive) NOT the desirable d-Ethylphenidate…..and Ritalinic Acid (inactive)

Opioid + Ritalin (Methylphenidate) + Ethanol/alcohol is AMAZINGLY Euphoric ….plus a Xanax or Valium even

Adderall & Vyvanse (d-Amph) I’ve had…….Adderall I’d select but Dexedrine first……but Ritlain (Methylphenidate) to me is Sooooooo euphoric & pleasurable plus its improved safety profile……far less cardiovascular taxing then the Amphetamines easily . Only Desoxyn / Methedrine (d-Methamphetamine) is safer cardio wise
 
Dextro .45 said:
Ritalin (Methylphenidate) is VERY euphoric & pleasurable……nearly identical to Cocaine, both compete for the same binding receptors at the monoamine transporter DAT/NET (Cocaine DAT/SERT/NET)

Taking Ethanol with Ritalin increases d-threo-Methylphenidate (Focalin) by 40% SIGNIFICANTLY enhancing euphoric properties in all study participants. Also produces Levo-Ethylphenidate (inactive) NOT the desirable d-Ethylphenidate…..and Ritalinic Acid (inactive)

Opioid + Ritalin (Methylphenidate) + Ethanol/alcohol is AMAZINGLY Euphoric ….plus a Xanax or Valium even

Adderall & Vyvanse (d-Amph) I’ve had…….Adderall I’d select but Dexedrine first……but Ritlain (Methylphenidate) to me is Sooooooo euphoric & pleasurable plus its improved safety profile……far less cardiovascular taxing then the Amphetamines easily . Only Desoxyn / Methedrine (d-Methamphetamine) is safer cardio wise
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Too bad I abused the fuck out my prescriptions lol. Those days are long gone, thinking about going in to get Spravato for my depression which is gonna end up killing sooner or later. That I know I can get because I can't use any of the psych drugs anymore I get to many side effects. I have a liberal psychiatrists and had her since I was 10 I give her a break because shes very kind just brainwashed by the system.
 
notsmokeymcpot42088 said:
^ Facts - shooting oxy is not great for many reasons. Morphine I would empathize with ...

100 - 125 mg methadone a day as you know it would cost you a damn arm and a leg to get a good high on pharm pills (Perhaps literally if you insist on IV'ing *rimshot*)

NOW THE REAL ISSUE -- said serotonin toxicity. I just said in another thread somewhere nothing scares me like serotonin syndrome and I did not know it could be gained through poly opiate abuse --- and wonder a bit....
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After I started on Subs, I started noticing serotonin syndrome symptoms whenever I tried to take SSRIs.

I tried to explain to my doctors that I don't think I can handle SSRIs on Suboxone because I believe Suboxone MUST be playing some role in serotonin, even though it's not recognized as a serotonin realeser or reuptake inhibitor or anything.

But check this out -
pubmed.ncbi.nlm.nih.gov

Serotonin syndrome triggered by a single dose of suboxone - PubMed

Suboxone (buprenorphine/naloxone) is an oral medication used for the treatment of opiate dependence. Because of its mixed properties at the opiate receptors, buprenorphine has a ceiling on its euphoric effects. We report the first case of serotonin syndrome caused by buprenorphine and review...
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

I find this rather odd that somebody could get serotonin syndrome from buprenorphine alone if it has ZERO effect on serotonin whatsoever. But it's clearly been documented. Yet there's still no research out there about what buprenorphine might be doing to serotonin to cause such events.

I imagine Methadone probably affects serotonin. It's not just an opioid, but also an NMDA antagonist. It's quite interesting though.
 
Hey, good to see you still here @4DQSAR !! :D
I took a long break from here cause I was tired of people ganging up on me & bugging me.
But I've been missing talking to intelligent & like-minded people, so I came back!

Hope you're doing good man! Cheers!
 
Single cases are often classed as idiopathic side-effects.

That's just doctor-speak for 'we don't know why'.

Each of us has our own unique and complex biological systems and there is almost no medicine in history that hasn't seen rare but real cases of unexplainable side-effects.

MOR and DOR ligands are known to act on certain parts of the brain to increase serotonin efflux while KOR ligands tend to reduce said efflux.
 
DeathIndustrial88 said:
After I started on Subs, I started noticing serotonin syndrome symptoms whenever I tried to take SSRIs.

I tried to explain to my doctors that I don't think I can handle SSRIs on Suboxone because I believe Suboxone MUST be playing some role in serotonin, even though it's not recognized as a serotonin realeser or reuptake inhibitor or anything.

But check this out -
pubmed.ncbi.nlm.nih.gov

Serotonin syndrome triggered by a single dose of suboxone - PubMed

Suboxone (buprenorphine/naloxone) is an oral medication used for the treatment of opiate dependence. Because of its mixed properties at the opiate receptors, buprenorphine has a ceiling on its euphoric effects. We report the first case of serotonin syndrome caused by buprenorphine and review...
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

I find this rather odd that somebody could get serotonin syndrome from buprenorphine alone if it has ZERO effect on serotonin whatsoever. But it's clearly been documented. Yet there's still no research out there about what buprenorphine might be doing to serotonin to cause such events.

I imagine Methadone probably affects serotonin. It's not just an opioid, but also an NMDA antagonist. It's quite interesting though.
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what an unlucky person/situation!

I try and stay away from SSRI's --- my ability to trip has been affected by sub ( I think, or excessive nbome and lsd ) I lean towards the suboxone having something to do with it.
(of course the benzos in the system doesnt help but at 2mg a day I should be able to get through that)
 
@notsmokeymcpot42088 - If nothing else, it seems that most antidepressents blunt or even stop the action of entactogens and psychedelics. Long, long ago in The Netherlands I was gifted a (very small) bottle of liquid crystal LSD and at first I thought it was a con. I kept on taking more and more until eventually it DID work.. but then it lasted for 48 hours. Before anyone points out acid can't do that, well, all I can say is that if the half-life is 2.5-4 hours, at some point whichever enzyme oxidizes the stuff must eventually be overwhemed.

I can remember thousnds of tiny 'Fred The Flour Grader' men walking all around the room and across every surface.

BUT I couldn't reach ego death which is what I look for in a psychedelic. Just cease to be a person and explore the universe while quietly lying on my bed.

freeimage.host

ftfg

Image ftfg hosted in Freeimage.host
freeimage.host freeimage.host
 
4DQSAR said:
@notsmokeymcpot42088 - If nothing else, it seems that most antidepressents blunt or even stop the action of entactogens and psychedelics. Long, long ago in The Netherlands I was gifted a (very small) bottle of liquid crystal LSD and at first I thought it was a con. I kept on taking more and more until eventually it DID work.. but then it lasted for 48 hours. Before anyone points out acid can't do that, well, all I can say is that if the half-life is 2.5-4 hours, at some point whichever enzyme oxidizes the stuff must eventually be overwhemed.

I can remember thousnds of tiny 'Fred The Flour Grader' men walking all around the room and across every surface.

BUT I couldn't reach ego death which is what I look for in a psychedelic. Just cease to be a person and explore the universe while quietly lying on my bed.

freeimage.host

ftfg

Image ftfg hosted in Freeimage.host
freeimage.host freeimage.host
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Absolutely true -- I am not currently on any anti depressants. I honestly found I would rather be able to roll/trip whenever I wanted as they did nothing for me. ( cant blame the pills, I question the diagnosis; but I don't for reasons you could prolly deduct )

Now just the 2 mg kpin and 1 of bupe --- oddly I seem to nod everytime I take mushrooms. Like 3 - 5 grams dried -- than wake up and they aren't fake I can feel something. But at that dosage the walls should be breathing at least?

Same goes for the last few hits of lsd I had took -- without the nod; I feel the comeup --- than it just never breaks into a full trip.

IDK haha not that big of a deal as I dont have access to jack shit lately or in the forseeable future --- I still dont love it though!
 
Dr. John Thackery said:
the rush and the ritual.
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I guess we have different priorities. I am concerned only with my legally prescribed meds taken properly. Opiods are a tool for managing pain or at least lessening it enough to not be miserable from pain.

At least in my case. And they are great without shooting them, or years ago were. Now it wouldn't give, me or someone on long term chronic pain management a rush. Even smaller doses produce high tolerance while being able to control pain some.
--‐----‐----
In the past I was only interested in the ritual of opening the bottle or I suppose cans of beer and pouring them into a big plastic cup,lol.

I am not an IV drug user, so I don't understand the ritual. The ritual of trying to find a vein, and going through the whole mixing of it with water and heating the spoon and injecting seems almost masochistic and much more dangerous.

I would not even be able to come close to being able to shoot a large enough of a dose of Oxy to get a rush. Too much mass with fillers and binding shit.

Besides ruining veins seems horrible, not that I am afraid of needles. I suppose that getting high off it; and being able to eat without a lot of pain, are two different issues.

I have never wanted to shoot anything and I do understand that rush, kind of. Severe alcohol wd/s and the rush of pharmaceutical Dilaudid IV and Ativan( Lorazepam), was kind of a rush; especially when you are in horrible shape from countless severe alcohol wd/s and that warm feeling of relief from pain and all the other misery associated with having to deal with past alcohol wd/s is, very very pleasant.

But Oxy ir, today if it can be obtained might cause a rush if you haven't been on it it everyday several times a day for so many years.

But sublingually taken works guick and even just regular oral kicks in fast, 20 minutes or so, maybe longer for others.

Besides the ease of taking it( legally in my case because of a chronic condition) seems to the whole point. Besides recreationally tolerance builds fast and is very expensive from what I have read on here.

I suppose that people into the old school original Oxycontin, back ~20 years ago or longer were just taking a large conentrated dose and being able to shoot large amounts with less shit to add size to the IR ones( the no Tylenol ones of course) of today.

But, snorting it is a waste, up the butt, Hell No!! Shooting seems pointless( no pun intended,lol) with it working so well orally.
 
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