Oxycodone doseage

[Rio Fantastic]

How much oxycodone would I need to make me 'nod'? I've done it before and done up to 60mg over the course of 90 mins on 10mg lines...I get an awesome rush at the start but after that its just a nice opiate high but never actually nodding. If I wanted the full opiate experience, I mean REALLY high, how much should I take? Should I snort or take it orally?

I'm about 6'1 and 154 pounds by the way

 

[100mgbluepill]

If you go that far you will probably just end up throwing up.. But i would take like promethazine or maybe after you do your lines take some nighttime nyquil with acephetamine. That should make you noddd.

 

[Keif' Richards]

Getting the "full experience"? That's a toss up, because where I'm from, everyone snorts there oxycodone pills, and that's what we do to have a good time. In reality though, eating is the way to go with this particular substance. Time has slowly taught me this, as after two years of consistent using, I'm starting to break away and start taking them orally. It's just better in every way, providing you can wait the fifteen minute difference between onset times.

Oral bioavailability is higher by a factor of ~20% or so. It also lasts noticeably longer, which is great because this shit is expensive. To try to answer your question though... If you took 60mg without even a slight nod, or extreme drowsiness, than you could most likely bump it up to 100-120mgs. Keep in mind, I'm saying that you will "nod" and getting in that situation isn't always safe. By taking more, you are just getting closer and closer to a dangerous level of central nervous system depression which could mean a lot of bad things. Point being, have someone with you who won't be too fucked up to get help if its needed.

 

[BaybeX]

^WHOA. 100-120mgs? Are you fucking kidding me?
Someone without a tolerance, which it seems like the OP doesn't have too much of, should NOT being doing 100-120mgs of Oxycodone.
Start slow and see where it takes you.. if you don't feel as good as you'd like to at 60mgs, try 70mgs.. move up slowly as it's not that hard to OD on opiates, dude.

Don't start with 60mgs even if it didn't get you nodding last time. I'd suggest using some potentiators (diphenhydramine, white grapefruit juice, tagamet, etc) instead of dosing more Oxy. Take it slow.. you're going to end up nodding but throwing up if you do too much.

 

[Captain.Heroin]

Somnolence is more common with other opiates, I.E. hydromorphone or heroin, oxycodone tends to have stimulant-like effects for an opiate.

Basic dosage questions belong in BDD.

 

[Keif' Richards]

^WHOA. 100-120mgs? Are you fucking kidding me?
Someone without a tolerance, which it seems like the OP doesn't have too much of, should NOT being doing 100-120mgs of Oxycodone.
Start slow and see where it takes you.. if you don't feel as good as you'd like to at 60mgs, try 70mgs.. move up slowly as it's not that hard to OD on opiates, dude.

Don't start with 60mgs even if it didn't get you nodding last time. I'd suggest using some potentiators (diphenhydramine, white grapefruit juice, tagamet, etc) instead of dosing more Oxy. Take it slow.. you're going to end up nodding but throwing up if you do too much.

Read the post... It says he has done 60mgs and not gotten as high as he would like to be. Judging just by how he worded the rest of the post he wasn't that fucked up from it i.e. "wants to have a full opiate experience" or something to that extent. For the record I do not, and would never suggest 120mgs to someone with no tolerance, I was referring to this case specifically. Sorry if anyone was confused. I will admit that that advice may be a wee bit irresponsible though even given what the OP said, and going up slowly would probably be a better idea. I was just trying to decode full the "full opiate experience" comment if you catch my drift

 

[SeaDoc]

Empty stomach (like at breakfast), take orally with 4-8 oz room temp. to warm grapefruit juice. At 15-20 min. eat something like a whole wheat toast with hone or jelly. This is the recipe for me to get the absolute best out of high bio-available opiates.

Empty stomach = no competition

warm wgfj = increased absorption and 1/2 life, warm to speed dissolving of tablet.

chewy = mastication stimulates digestive process

whole wheat* = non water soluble fiber speeds stomach evacuation = getting it into small intestine where absorption occurs

honey or jelly = sweetness, again, stimulates digestion

*food generally speeds uptake of tables, but slightly slows capsule uptake.

SeaDoc

 

[Rio Fantastic]

Empty stomach (like at breakfast), take orally with 4-8 oz room temp. to warm grapefruit juice. At 15-20 min. eat something like a whole wheat toast with hone or jelly. This is the recipe for me to get the absolute best out of high bio-available opiates.

Empty stomach = no competition

warm wgfj = increased absorption and 1/2 life, warm to speed dissolving of tablet.

chewy = mastication stimulates digestive process

whole wheat* = non water soluble fiber speeds stomach evacuation = getting it into small intestine where absorption occurs

honey or jelly = sweetness, again, stimulates digestion

*food generally speeds uptake of tables, but slightly slows capsule uptake.

SeaDoc

Is it best to break open capsules and bomb them, even if its instant release? Or is it sufficient to just take them?

 

[SeaDoc]

Rio,

That depends on the med. No, when the capsule is protecting your stomach from some ingredient; otherwise, I would say yes. But, test a gel cap and I think you'll find that they dissolve pretty quickly.

Re: tablets vs capsules and food; I have seen the statement I made in several pharmacokinetics sections of drug info sheets.

SeaDoc