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  • BDD Moderators: Keif’ Richards

oxy vs hydro? I need answers about the two? mixing?

H

Help_Me?

Greenlighter
Joined
May 29, 2010
Messages
5
I have a couple 10mg oxycodone, and
a few 5mg hydrocodone, vicodin..
i was just curious about some things.
I have a fairly high tolerance...i can take 6-7 5mg hydros,
and 4-5 10mg hydros sometimes more...i havent experimented much
with oxy's thats why im curious i want to be safe any answers are appreciated.
Thanks in advance.
my questions are,

1. Are they safe to mix?

2. Whats the difference?

3. Which gives you a better buzz?

4. Is difficulty breathing from high doses normal?

5.Whats a safe yet fun dose for a person with a high opiate tolerance?

6. Ive heard both are codiene based? is this true? if not what are the different chemical compounds.
 
1. Yes they are safe to mix, just know your tolerance and don't overshoot it. You can use a dosage converter if you need to, like this one.

2. Some people find oxycodone more stimulating an opioid, otherwise not really much difference between them. Oxycodone is somewhat more potent (i.e. stronger mg for mg).

3. As the late, great Gary Coleman could have told you, Diff'rent Strokes for Diff'rent Folks. Some people prefer one, some the other, we can't tell you what you will like better.

4. Yes, this is from respiratory depression and you want to be careful here and don't add in any other CNS depressants (e.g. alcohol, benzodiazepines, etc) at this point.

5. If you take 40mg of hydrocodone as you say you do, which is not that high really, that is around 25-30mg of oxycodone using the opioid converter I linked you to. Your results may vary somewhat.

6. Read the Wikipedia pages for them, but I believe both were originally synthesized from codeine yes. I've read a few different synths for hydrocodone starting from codeine.

And now OP, in return for all that, I have a question for you: What the fuck are you posting this in Australian Drug Discussion for? We don't even get hydrocodone here? Also, did you use the search engine? All those answers could be found here on this site already.
 
Why is this in AusDD? You don't even get hydrocodone in Australia. I will attempt to answer your questions as best I can.

1. They are safe to mix in low doses, they probably increase the effects of one another so the first time you try the combo you should start with about 40% of your usual dose of each drug.

2. I believe hydrocodone is more sedating, as we don't get it in Australia I am not certain.

3. Which gives the better buzz is subjective. Oxy is more commonly abused because it is available in formulations that are not mixed with acetaminophen, if hydrocodone was available in 80mg tablets it may well be as popular or even more.

4. Difficulty breathing on high doses of any strong sedative is pretty normal although it indicates you are close to the danger zone, if not there already. Hydrocodone and oxycodone are both opioids, opioids are CNS depressants, so yes it is normal but you may want to try taking less to be safe.

5. You would have to define "high opiate tolerance".
http://www.globalrph.com/narcotic.htm this chart puts 30mg hydro equal to 15-30mg oxy.
http://www.pharmer.org/forum/discussion-prescription-and-otc-meds/opioid-comparison This one compares 4.5-6mg oxy to 16.67mg hydro. So going by these orally, mg for mg oxy is aout twice as strong. Surely if you have high opiate tolerance you know your tolerance to one or both these substances, those charts should help you figure it out.

6. Neither are "codeine based". Oxycodone and hydrocodone are both opioids that are synthesised from thebaine I believe.
 
^ I beat you to it, d_m! ;)

But I will correct for six in my post in that oxycodone is mainly synthesized from thebaine but can be synthed from codeine. Probably not as economical though.

I imagine hydrocodone is synthesized mainly from thebaine as well, but not sure.
 
Haha, only just! I wouldn't be surprised if both oxy and hydro can be synthed from codeine, but as far as I was aware thebaine was a more common starting point and almost certainly the way a pharmaceutical company would make it. Even if it was synth'd from codeine, it would be a bit of a stretch in my mind to call a medicine "codeine based" on that basis.
 
^ Yeah it was a mistake on my part, I've been waiting all day for a decent question to answer on AusDD and so I jumped right in without checking my recollections first! :|

I think also part of it is that recently I have been looking into those synth methods out of curiosity after another BL'er mentioned them to me and so have the codeine methods on the brain. I would bet that synthing from codeine isn't the most economical method and thebaine is definitely what the pharmaceutical industry seems to prefer. :)

ETA: Oxycodone was first synthesized from thebaine, my German isn't very good but I believe from the page I'm looking at hydrocodone was first synthed from codeine, just to sate the curiosity of anyone else out there. :D

ETA 2 - Electric Boogaloo: I hate saying things are 'something' based, it reminds me of people who used to say different pills were 'speed' or 'heroin' based. :p
 
Last edited:
Crankinit said:
Why AUDD? You can't even get vicodin here, afaik.
Click to expand...

He posted it in the australian section, so I thought i'd shoot it here to see what you codeine users might have to say.

I'll leave it here for a bit longer than shoot it off to BDD.

Moved.
 
sorry didnt mean to post it in the wrong place, im new to this n thanks for the help
 
Help_Me? said:
1. Are they safe to mix?

2. Whats the difference?

3. Which gives you a better buzz?

4. Is difficulty breathing from high doses normal?

5.Whats a safe yet fun dose for a person with a high opiate tolerance?

6. Ive heard both are codiene based? is this true? if not what are the different chemical compounds.
Click to expand...

  1. They're safe to mix, just don't over do it. Know your tolerance levels as Oxy is stronger then Hydro
  2. Potency. Oxycodone is stronger then Hydrocodone
  3. IME, oxycodone gives you a better buzz with less pills. But everyone prefers their own DOC
  4. You have to watch for CNS depression which isn't something to mess around with. Know your dosage and don't over do it. You can always take more 30 mins later or so if it's not the high you were looking for
  5. Only you know your tolerance and it's better to take less and have to re-
    dose then to take too much and not be able to take less. I personally take 30-40 mgs of Oxycodone but I know my tolerance levels and that just barely gives me the nods.
  6. Neither are codeine derived. I'm deathly allergic to codeine and I can take Hydro and Oxy. They are synthesized from Thebaine.
 
^ Hydrocodone was first synthesized from codeine. Your deathly allergy probably has to do with the fact that codeine is a very potent histamine receptor agonist, which is the same reason it can be fatal to IV.
 
And here I always thought, and believe I read somewhere, that hydrocodone was derived from codeine, and that oxycodone was derived from morphine. But with several answers saying thebaine is the root of both I will accept that. Could be that I read that the wd's from hydro were like codeine, while oxy wd's were similar to morphine.
 
Both oxy and hydro CAN be synthed from codeine, but they are economically non-viable. Thebaine is a much better alternative in terms of yield, and therefore profit.

OP your questions ahve been answered well so I have nothing to add. :)
 
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