Oral hydromorphone- better than advertised

[trippinspirals]

Mods- no hurt feelings if you think this thread is worthless

basically I just wanted to dispell the myth (IMO) of oral hydromorphone being so worthless. Doing any search for dilaudid or hydromorphone you will get a bunch of people talkin about how amazing it is to inject (and I have little doubt this is true) accompanied by the overall opinion that it is just crap when insuffated or taken orally.

For a serious opiate user orally probably isnt very practical with dilaudid, particularly because they are kinda scarce and it would take a ton of those little 4mg pills.

However for those with little tolerance, like myself, they do the job just fine. Taking orally 2.5 4mg pill and snorted the other 1/2 and I was quite impressed. It felt like over 30mg hydrocodone and hit hard enough to where I was having a little trouble walking- which under 30 mg hydrocodone has never done to me. So I found them to be quite under-rated.

Now if it takes an oxy 80 for you to even think about feeling something, then dilaudid orally prob isnt for you.

anyone else had a pleasant experience with oral/nasal administration?

 

[geetered]

Well it dosent necessarly suck when taken orally but as far as oral opiods/opiates go hydro/oxy-codone are the best for oral use... hydromorphone also have a high street value where im at 4mg-$10 so its just a waste of $$$ if you take them orally seeing as how most opiate users could eat up 20mg easily, and when injected its a very nice rush so i just think its a waste when taken orally but thats just my opinion.

 

[anafagodma]

You are right. Certain opiates are simply ineffective when swallowed. Morphine and buphenorphine are two very good examples. ( I know that buph is currently in use in VERY high dosages for detox and I don't know whether these pills are swallowed, but the traditional formula for buphenorphine pain-killer is a 200 microgram pill that must be taken sub-ligually in order to be effective).

Regardless of tolerance, any user will have a more positive reaction to opiates like hydromorphine or oxycodone taken when swallowed than to opiates like morphine ingested the same way, because of the part of the body in which metabolism takes place and how long the metabolism lasts. Orally, for instance, 90 percent of morphine is metabolised in the "first pass" through the liver. Without involving a bunch of scientific mumbo-jumbo that may be less than accurate, I can at least tell you with certainty that the more delayed the metabolism of the drug, the more "effective" or "potent" it seems. All of the non-narcotic accompaniments meant to potentiate pharmaceuticals act by slowing down the metabolism of the drug. That's what all the grapefruit threads are about, in a nutshell. However, it's much better on your body to just take a drug that is inherently metabolized slowly than to artificially slow inhibit the action of your liver.

I have a high-tolerance, and I, too, enjoy hydromorphone. It *is* a waste for me to take it orally, but if I had access to amount I'd need to use it orally, I would take that over oral morphine any day.

 

[brink50]

thats the only pill safe to inject too

 

[Crimson Cloud]

^It is not safe to shoot any pill, including Dilaudid. It may be "safer" than other pills, but it is still not safe.

 

[Tri-nity]

I would most likely snort dilaudid.
I believe it's water soluble and theres not to many binders and fillers in generic K4's or so I've heard.

I would imagine 25mg would be a good dose, but I have a tolerence so this doesn't apply to everyone.

 

[uenjymyself]

16mg oral hydromorphone *should* do the same thing as 42.67mg of oxycodone oral however(apart form the obvius diffrences) ok listen morphine works prally hydromorphone works rrally it has to,if it dident then well why would it be used? it may prodce a muhc "shittier" high then when IV.ed and well i always pass on them becuase i dont use needles anymore but if i had the money and had no tolernence then they would get me high in theory 1 8mg shoiuld get me off although i doubt it would feel anywhere as goods asan OC 20 wich according to the dosage converter it is equal to

 

[brink50]

well these dont work on the euphoria receptors as much as like oxycodone or hydrocodone do they. i see what you mean by equal i guess but these just have alot of sedation and painkilling effect to me

 

[kharma_bum]

I don't understand why you would eat 4mg and snort another 2mg? Why not just snort all 6mg?

 

[_high_life_]

snorting hydromorphone is the way to go if u dont like needles, a good 2-3 4mg pills will get my nice and blissed out but the iches always seem to start at my noze and thats a pain but not all bad

 

[kalt_kalt]

Ok, this is something i have experience with. Taken orally, sorry, they suck. Hydrocodone works better. It's not that hydrocodone is stronger (far from it), it's all about bioavailability. Taken orally, hydromorphone has a very low bioavailability. My tolerance to opiates is moderate, i'm not an addict, and it took about 30mg of dilaudid orally for me to feel the slightest thing (extremely disappointing). 30mg of hydrocodone would have been much better. Now, 4mg of dilaudid IV... that's another story. Holy crap, greatest experience of my life. Save that for birthdays and special occasions. That rush.... wow.

Bottom line, dilaudid is worthless orally (maybe if you are the type of person who would get zonked out with 30mg codeine it might do something for you) but pill for pill, mg for mg, plain old vicodin is a better oral narcotic than is hydromorphone. An 8mg dilaudid taken orally wouldn't get rid of a mild headache. Rather have a 10/325 norco.

Note that the only truly safe dilaudid to inject is the Knoll (name brand) white 8mg one (aka the "K8's"). No colorings and it dissolves completely in water. Always filter, just to be safe, though. Do not inject generic dilaudids.

brink50: those "euphoria receptors" are the mu receptors and hydromorphone, oxycodone, and hydrocodone are all mu receptor agonists. The issue is bioavailability when taken orally, not that they act on different "euphoria receptors." Hydrocodone and oxycodone have a much higher oral bioavailability than does hydromorphone, which is why dilaudid pills are such a crappy medicine (taken as directed, anyway). It's also why they're not prescribed too often. Percocets are much better as far as pills go.

If you're afraid of IV, do it IM. A shot of dilaudid in the ass (not up the ass, I mean using a needle IM) works very nicely, but you need to use more (2-3 times the amount) of it than you would IV. Of course, don't *really* do any of this and follow your doctor's instructions....

 

[Chemboy]

I enjoy 25mg of Hydrocodone orally on a empty stomach, does the job. Wish I could find some with no APAP so I can snort!

 

[kalt_kalt]

hydrocodone is not hydromorphone (dilaudid).

 

[psychetool]

I find it funny that people make definitive statements about drugs which effect each person differently. It seems that Trippin_Spirals just enjoys a different method of ingestion then you. His method doesn't suck plain and simple ~ it works for him. I also enjoy a nice 4 hydromorphones orally. Sure, it may not compare to an oxycontin ~ but it still does the trick right well!

 

[psychetool]

So, Diluadid is neither sucky or worthless orally. I will once again repeat this quote I have seen posted again and again at bluelight. "Different strokes for different folks."

 

[Piper methysticum]

I woulds say Hydrocodone and Oxycodone are the best for oral consumption. I have insufflated 4mgs of Hydromorphone to little effect, while 4mgs IV slammed me. Then I insufflated 4mgs after taking 25mgs of Hydrocodone orally, and I again got slammed. I not only had the "strong" Opioid buzz, but I had the euphoria from the Hydrocodone.

 

[negrogesic]

^^^Yes the "codones" are quite orally active, in comparison to the other semi-synthetic drugs. Of all the pantherenes class of opiates, oxycodone and hydrocodone are the most orally active. Oxymorphone is also relatively orally active, but is much better IV'ed, just as oxycodone is much better IVed, but is still orally active. Hydromorphone is ok not IVed, i think its best rectally than oral or snorted. But none of these routes of administration compares to IV. Fully synthetics drugs (fentanyl, methadone, levorphanol) generally have a much higher bioavailability than semi-synthetics and morphine/codeine.