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Opioids OPANA ER nasal spray question (it's no in the MEGA)

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MAJ.Pain

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Jun 27, 2010
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OPANA ER 20 MG , Tampering Advice...

hello yall,

need advice on opana ER (Oxymorphone Extended Release) 20 mg. The 5 mg IR tablets (immediate release) work much better, mg for mg thinking it's around 2x stronger with the IR tabs.
The ER tabs are not just absorbed slower, but the total absorption (Bioavailability %,) is far less with ER tabs. my guess is about 20%, and the IR tabs are around 35-40% bioavailability (BA)

Route Of Administration: Nasal (snorted) , both tabs prepared in the same fashion, crushed in between a folded piece of glasine paper (the type of paper that is used in packaging heroin), then quickly broken up with a razor. (with the ER tabs the coating is carefully removed with a razor first)

Is there a way to process the ER tablets, so they do NOT gel up in the nose? to be quickly absorbed in the same way that the IR tablets are?

How would do you prepare your ER tablets?

Are there any drawbacks to your methods?

(i do understand that these tablets maybe dangerous to the lungs) maybe your method safeguards you from lung damage?



Thanks a bunch!
-Pain :|
 
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yes sir, already do that, have a necessity to do so, because the half-life is not very long after nasal administration, orally it's supposed to be very nice around 7 hours (~10% BA), but IV/IM/SC (100% BA) it's very short at around 1.5-2 hours, nasally (~40% BA) would say it's around 4 hours, and pronounced analgesia lasts around 1.5-2.5 hours after administration.

Using around 5 mg, every 1.5-2.5 hours during the daytime, and about 1-2x during sleep, as needed. a semi withdraw syndrome sets in at about 6-8 hours after last administration.

the problem with the ER tabs is the analgesia would say is around HALF 1/2 the IR tabs analgesic potency.

some solution is needed to increase the BA of the ER tabs for sure.

***** Have searched and searched on making a liquid solution for a nasal sprayer, but not really confirmed weather or not these methods work or not, or what would be the best... Information is needed to properly layout a method for a nasal sprayer application, or some other method of administering nasally. *****

please someone, if you have info on a proper tech for making a nasal spray of Opana ER, please post the in depth details here, or in a private message.



Thanks a bunch yall,
-Pain :|
 
From memory (we do have an oxymorphone mega thread, use google)
1. Smash the fuck out of your ER pill
2. Wash with 99% (or better, dry) rubbing alcohol (isopropanol)
3. Collect and filter the isopropanol, evaporate it to yield oxymorphone HCl plus some minor impurities.
4. Dissolve into a nasal sparay bottle

I suggest you consult the mega thread.
 
first off i need to say, I Have checked the !@#$ MEGA thread and there's like 2 posts on nasal spray, and it's bulls#@.

that said, i need SOLID advice on how to make a nasal spray of OPANA ER.

1:step by
2:step by
3:step.........

SOLID well thought out advice, with the experience to back you up, or discussion that is appropriate for this topic. NO BULL...



and by the way, just so you know , this actually qualifies as HARM REDUCTION since these pills contain dangerous substances for your lungs, and a nasal sprayer would most likely totally reduce the risk to 0.



THANK YOU VERY MUCH!
-Pain :|

P.S. and ffs a thread about OPANA ER, and it's harm when snorted should be a sticky, and with it a way to make a nasal spray , because people are damn well going to get there 40% BA compared to that poor ass oral 10% BA.

yall claim this is for HARM REDUCTION then you jerk people around when they are asking for solid advice.
 
It looks like Sekio gave suggested steps in your last thread....

Not sure what more there is to say on it. Grind pills really really finely, extract oxymorphone with dry IPA, filter, evaporate liquid to check your work (make sure you've gotten something around what you expected out of it), dissolve in appropriate amount of water or water/ethanol mixture, such that the concentration of the liquid will give you the desired amount of oxymorphone per spray of the nasal spray bottle.

You're going to want to do some measuring to figure out how much liquid gets sprayed per spray on the spray bottle, and stuff like that. I don't see much in terms of relevant information in the megathread either, so it looks like you'll need to nail down the details of the process yourself (and post them in the megathread for the next person who wants to do this).

I have to say, I do think they've been overly aggressive about locking threads and referring people to the megathreads, when the information isn't really covered there (or is well hidden enough that it might as well not be). But that is a discussion that belongs in the BL support forum or in PM to the mod who locked your thread, IMO.
 
Opana ER extraction
I just made an Opana nasal spray.
Opana ER and silicosis

I found these searching for some combination of "opana", "nasal spray", "bluelight", "extraction" on Google. if you seriously can't figure out how to make a nasal spray now, I fear for you...

I got a PM re: the earlier closed thread. If you would rather I keep all the threads with personalized medicine advice, speculation, and questions that have been answered over and over again open, then I suggest you contact an administrator or senior moderator.
 
NO opana ER spray info on BL...

Opana ER extraction
I just made an Opana nasal spray.
Opana ER and silicosis

I found these searching for some combination of "opana", "nasal spray", "bluelight", "extraction" on Google. if you seriously can't figure out how to make a nasal spray now, I fear for you...

I got a PM re: the earlier closed thread. If you would rather I keep all the threads with personalized medicine advice, speculation, and questions that have been answered over and over again open, then I suggest you contact an administrator or senior moderator.
Click to expand...

^posted by MOD sekio or whater his name is^

SO sorry but the links you posted, then closed the thread stating that there is all the info needed on the subject, is totally FALSE.

more info on the subject is needed. Opana ER nasal spray, or an extraction for the sole reason of intra-nasal use. us pain sufferers need these tools in a world that holds us commoners back from access to more adequate relief.

**** also i have gotten multiple PM's of people that are looking for the same exact information, also stating that the info is not anywhere on bluelight. sorry but we know how to use the search feature, and it's not there. ****
 
If you have a problem with a mod, you should take it up with the Admins. If you have a problem with them, take it up with the owners.

I have no problem with discussion regarding a nasal spray for OPANA ER which would reduce the risk of silicosis, but you can't just have open attacks on mods on this forum.

WE ARE CURRENTLY DISCUSSING OPENING THIS THREAD. PLEASE DO NOT START A NEW ONE.
 
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