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Harm Reduction Olanzapine and Alprazolam Interaction

wooger

Bluelighter
Joined
Aug 3, 2005
Messages
765
Hi

I have been taking olanzapine as a sleep aid for around one week at 5mg because I had nothing else. Today I received my alprazolam (YIPPEEEEE) but looked up interactions, some of which have proven fatal! :| This seemed to be through IM use tho...

would they still be dangerous to combine them orally?

thanks :)
 
Hi, can't say whether it would be safe, but your on a reality low dose of olanzapine, did you get prescribed these meds? If so I would follow your doctors advice as to whether they can be taken together, if your doctor knows you are on both these meds I'm sure he/she would have mentioned any interactions. Cheers acidtek

Didn't read your post properly but with fatal reactions, fuck that!
 
Hi

Thanks for replying :D well where I read about the fatalities was here: http://www.drugs.com/drug-interactions/xanax-with-zyprexa-133-54-1744-1113.html

Though it seems to be IM use that is the problem... so I dunno about orally..

oh and I am not prescribed either of these... the olanzapine was my sisters but she no longer takes it so I was just using a lil to help me sleep.

so yes, should I just forget it until the olanzapine is out my system?
 
you used the drugs.com interaction checker right? those deaths were related to IM olanzapine during post-marketing use along with other drugs (IM'd), benzodiazepines just happened to be one of the other drugs which were used in combination alongside anti-psychotics. i would say adding in the IM benzos and AP's that have the potential to induce hypotension, bradycardia, and respiratory or CNS depression [1] would be a major factor of those deaths.

there is still going to be risk for a potentially fatal incident but given you're taking the drugs at the therapeutic doses prescribed you should have little to worry about.

has the doctor prescribed these in combination for yourself? i would be asking him these questions if so to get a professional opinion and answer.

[1] -

ha, got beaten to it! had to stop and roll a cig and have a piss while i was replying :P
 
ive been on zyprexa (olanzapine) 20mg for bipolar disorder for long enough that i lost count, also prescribed by the same dr... 5mg/day clonazepam.. no bad interactions, but than again alprazolam isn't clonazepam.

Have tapered off the clonazepam daily and only take it as needed now but was on it a long time.. legally and illegally about 7 years. Also used a lot of phenazepam along with it chasing a high i never got.
 
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^^ well done for cutting down on the benzos :D

also, the site said it was benzos in general which caused a problem and it tended to be IM use, if you guys are fine and prescribed by a dr I'm gunna go ahead and assume I will be fine too but thank you for all your input :D.
 
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