I don't see any problem with restarting. I'm on oxy daily myself and had to figure out the constipation thing. Frankly doing an enema each morning is the perfect solution. I had no problems then at all but eventually taking lots of psyllium and eating lots of fiber, like beans and raw veggies I usually don't need the enema now. I find enemas quite painless on every level, even pleasurable. I even started plugging my oxy for a better effect. It's not a big deal. It's a hell of a lot better than suffering serious constipation. You can get a decent enema bag on Amazon or such for cheap. Good luck.