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Opioids OG Octagonal Opana ER - MEGA THREAD - can't find YOUR thread? check here.

So...

I get 150 40 mg ER's and 120 10mg IR's a month. usually take the 40's in he nose, was getting rid of all the 10's (didn't want to take too many) been on the same dose for almost 6 monhs though so not nearly as effective as it was. thinking about adding in some 10's IV. I have a long history of IV heroin use, very familiar with needles/shooting, not so much shooting pills though. who has some tips for me? I'm looking to get the most out of the least medication.


any tips would be appreciated

<3
 
I find it funny how all of u keep telling each other the ER opana's aren't injectable so don't attempt it , u would need a lab blah blah etc etc , im just a dumb white boy from florida and i can extract 18mg out of a 20mg pill give or take easily , look up injecting opana er on BL and thread's will pop-up on one of these thread's lies a proven and used by me several time's on the second page of this thread , i call it the alchohol method (isopropyl) 90+% , but the key to this is if u dont do it exactly right , u will fk it up to where either u didnt kill the gel , or u fried the oxymorphone out of your solution , it take's me about 10-20 min's start to finish to complete a opana er extraction , most i ever iv'd at once was 30mg , and i only did it once because it was way to powerful for even me with my tolerence ,


( [email protected]) if u wish to talk about anything on your mind ;)
 
This medicine is GARBAGE.

The only way to use it apparently is to crush it and fill your nose with gel. Oh joy!

I have literally been eating these like CANDY.

I was subscribed the 40mg and they DO NOTHING. SO I tried to take the coating off, chew them up like and oxy and swallow and NOTHING.

We are talking EIGHT 40mg OPANA orally and NO NOTICABLE EFFECT WHATSOEVER HAPPENING.

I am not interested in snorting a bunch of SILICA into my lungs which is an ingredient in the TIMERrx system. SILICA over a long time = CHRONIC BRONCHITIS, damaged lungs.

I don't think I have ever encountered such a fraud.

I am SO SAD. I was so happy to be getting OPANA and have some new strong super med, but the TimerRX doesn't RELEASE ANY MEDICINE AT ALL.

I mean literally NOTHING HAPPENS WHEN YOU TAKE THESE PILLS. I'm so pissed, because my expectations were through the roof and I was so happy to get these.
 
according to the website:

40mg OPANA oral is equal to 80mg OXYCONTIN oral 8)

Hahahahahahahahahaha

It would be funny if there were not pain patients suffering due to this SILLY conversion chart.

The truth is about 140-160mg OPANA oral is equal to 80mg OXYCONTIN ORAL.

What a joke! What is sad is my practicioner won't prescribe Oxycontin because of the "HYSTERIA."

So maybe she will prescribe 120-180 40mg OPANA because that is what I will need.

This medicine is the biggest load of shit ever sold to the pain community - I notice it says DO NOT DRINK WITH ALCOHOL.

I think I will take my next dose with a shot of Tequila!
 
i know this is an er thread but i need help. im prescribed 90 10 mg irs a month (and also 120 350mg somas) i have a long time opiate history at one point iving 1000 mg heroin a day.because of my high tolerance its not helping enough for the pain of 2 car accidents and i don't want to lose my current script and have lawsuit complications.im iving them but i need advice on maximizing each shot without using more than one at a time the cotton gets cloged and less thn half of the liquid makes it in to the needle.i have tried rectal admin but its hard to have empty bowels 3 times a day.please if someone can help it would be greatly appreciated.
 
Potency, is the strength per mg of a substance that is in the bloodstream.

Bio-availability determines the proportion of substance that makes it into the bloodstream when administered a certain way.

Therefore the overall effect that a given amount of substance has on the body is a combination of BA and potency.

When talking about JUST potency, one would have to IV the same amount of two different substances in order to compare, because it is consistently 100% BA regardless of individual, so BA is eliminated as a factor. This is why morphine is more potent than oxycodone, even though more morphine must be eaten than oxycodone for equal analgesia.

I think a term should be invented to distinguish between potency and overall effect (which needs BA as a variable). Maybe "bio-potency" would be a good term for relative over-all-effects of different drugs. e.g. "Oral oxycodone is more bio-potent than oral morphine."

The Term you are searching for is Efficacy;

http://en.wikipedia.org/wiki/Efficacy#Pharmacology

(I hate quoting wikipedia btw, its usually wrong, this is correct though).
 
PAINGAME -

Uh, no. While I can't accuse you of lying, I can say with certainty that 40mg Opana is absolutely something to be respected, and to suggest that one must take more Opana than oxy to get similar results is irresponsible at best. Should someone decide to use your post to rationalize an overzealous dose, they would likely be in for a very unpleasant surprise.

I had a huge Opana habit, which I will not recap here since it is readily findable in this forum. The relevant point is that for the vast majority of users, Opana will prove at least twice as strong as oxy, regardless of administration. True, one can debate the merits of the attempts to quantify subjective elements like euphoria, rush, etc...but in terms of potency, best to overstate the issue rather than understate, as one generally cannot 'untake' their dose, and with Opana, the discovery that one's dose might have been a tad too big might come later in the game than with, say, oxycodone. In my experience, the full recreational potential of Opana is not realized until one develops both a tolerance big enough to take a significant dose (for me, this started around 20mg rectally, which took some time to reach), as well as the so called "acquired taste" aspect of drug appreciation. Think about opiate naive people who try heroin as their first opioid - most don't come back to it because the pain fact is they just do not have the experience required to really enjoy that drug. For most opiate naive or low tolerance persons, hydrocodone would be preferable because it is less imposing, less intimidating, less nauseating, etc. However, as those with experience using H know - it just gets better and better each time (until one crosses a certain barrier that needs no elaboration here) - and the same can be said for Opana imo. Indeed, 40mg Opana rectally (my highest single dose - though I did reach multiple doses per day) provided a euphoric rush that far, far surpassed that of any other drug I had ever tried. That being said, the 'rush' aspect of those hits were very short, and the actual remaining high - think in terms of about eighty percent of the time spent under the influence, is actually quite comparable to the best part of a high dose morphine high. It's very, very smooth and sedating, yet clear headed.

Even here I've already digressed into subjectivity - I apologize - to reiterate my point, please go back and edit your posts suggesting that Opana does nothing at the doses you took, if for no other reason than it's just one less possible instigation of tragedy.

BTW, this is not intended as a criticism or flame, but rather an attempt to get you to understand that what you post here does get read, and therefore could be influential, and in a case such as Opana, mistakes of very little magnitude can have drastic consequences.

Peace.
 
^yeah, I wouldn't expect him to edit his post, but i don't think it is to be taken to0 seriously. i would say 4-5mg of intranasal opana off of a 40er is equal to about 20mg of oxycodone, and lasts several times longer than oxycodone. also, opana takes much longer to kick in than oxycodone, so careful about thinking you did not take enough and redosing too soon.
 
Guys, we are all talking about the same thing here, right? Bioavailability and potency are extremely similar. For instance since Opana has only 10% BA and Oxys have around 85% (I'm only referring to orally) - in this example Oxycodone would be the stronger one, am I right? And yes I know that Opana is supposedly 4-5 times stronger in dose and analgesia but when taken orally it really doesn't do much. I know one of you is going to correct me but thats okay. It's what BL is here for!

The oral conversion comparison between oxymorphone and oxycodone already takes bioavailibility into account. Orally, 20 mg's of oxymorphone converts to 40mg's of oxycodone, even with the much lower bioavailibility. Whatever dose of oxymorphone you take, even only at 10% bioavailibility, is equivalent to twice that dose in oxycodone for pain.

If we are using an IV conversion, both having a 100% bioavailibility, 20mg's of oxymorphone would convert to something likely in excess of 100mg's of oxycodone, 5 times or stronger mg per mg. Because the conversion chart is oral and the major difference in bioavailibility with the ROA, the difference drops to double the difference mg per mg. What this tells us is that oxymorphone is extremely potent.
 
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^^ Not 100% about this, but when IV, the conversion is much more than 5x. The opiate calculator I used stated 1mg OM to 20mg OC. That means IV OM is 20x oxy potency.
 
^yeah, I wouldn't expect him to edit his post, but i don't think it is to be taken to0 seriously. i would say 4-5mg of intranasal opana off of a 40er is equal to about 20mg of oxycodone, and lasts several times longer than oxycodone. also, opana takes much longer to kick in than oxycodone, so careful about thinking you did not take enough and redosing too soon.

I seriously don't understand!!!!

I have the 40mg stop signs and I swallow three of them and NOTHING HAPPENS.

I am not joking - and please no one else take this post as advice as to what you should do - this only applies to me.

If I take 4x80mg OC I am nice and toasty high within about 1 hour. Yet I take 120mg OPANA and feel nothing. I mean it does not even keep me from getting sick.

Could there be something wrong with me that my stomach is destroying it? Am I immune to OPANA? It is the most bizzare thing in the world!

I am so upset that I have this wonderful (apparently) narcotic and I CANNOT get HIGH OFF IT.

I think truly I am immune to OPANA. It is SOOO FRUSTRATING!!!

That being said I have only taken them orally.

What should I do it is making me so sad to waste this medicine - if I take it orally it does nothing. Maybe I ned to try snorting one of them.

How is it that Oxycodone works so incredibly when I eat it but OPANA does nothing? Could I have a problem with my metabolism???

I am going to report back as this is gone beyond all frustration for me.

I said I would never try to plug or snort but maybe I will because OPANA has 0% oral bioavailability for me - 0%!!

Again - I am a long term pain patient please kiddies realize this does not apply to you - however this is the first opiate I have ever encountered where IT DOES NOT WORK ON ME. (AT ALL!!) I might as well be eating sugar pills.

- Oh I am mixing with Oxycodone - if you take Oxycodone and OPANA together does that mean the OPANA won't work??
 
^^ You must be a very poor metabolizer (of opana). Keep in mind, ingesting opana with a full stomach (mainly high in fat) can nearly triple the BA. Therefore, try eating it after a filling, greasy meal. If fail, try snorting, also after a meal. You can't go wrong with this, but make sure you crush very thoroughly and divide your dose into many smaller lines to snort over 10-15 minutes, splitting between each nostril. This helps circumvent the effective anti-abuse gel.
 
^^ You must be a very poor metabolizer (of opana). Keep in mind, ingesting opana with a full stomach (mainly high in fat) can nearly triple the BA. Therefore, try eating it after a filling, greasy meal. If fail, try snorting, also after a meal. You can't go wrong with this, but make sure you crush very thoroughly and divide your dose into many smaller lines to snort over 10-15 minutes, splitting between each nostril. This helps circumvent the effective anti-abuse gel.

VICTORY!!

I got a 40mg stop sign and carefully removed the entire outside coating with a razor.

Then I crushed it up inside a folded paper wad, until it was a perfect baby powder.

I just snorted the whole thing half in each nostril and actually I am a little frightened - this is the first time I have felt like I may have taken too much opiates in a LONG LONG time.

Apparently I have zero ability to metabolise these orally. I will be snorting them from here on out.

Let me tell you though - snorting 40mg is too much - DO NOT DO IT. I have a huge tolerance and I feel scary high.

So I agree finally that these OPANAS are really strong - WOW my ears are ringing.

So I guess I am snorting all my OPANA from now on.

I need some advice since I have never snorted anything before:

1) Is it safe for my lungs and nose to snort 90 40mg OPANA every month?


This rush reminds me of speed. Does anyone else feel that way? I think I am going to have to run to bathroom....
 
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Wow I can tell you I have never even felt a minor HINT of this while taking them orally - literally I could eat them like candy!

One time I even took 5 of them and nothing happened.

I have been so depressed about this issue for some reason I think the Timer-RX system releases ZERO drug into my body when I just swallow them.

So sad I cannot metabolize these pills without doing something I am really not supposed to.

I am already coming down some - that was a HUGE rush to snort the 40mg - actually it was not as strong as I thought - just an incredible rush my toes were tingling. I am still really high as a kite.

I WILL NEVER SWALLOW ONE OF THESE AGAIN!!

I am kind of sad though too - in all my life I have always taken my medicine the way it was prescribed by just swallowing it.

So I feel I crossed a line kind of - however you have no idea my frustration at having all these OPANAs and they might as well be jelly beans!!!

What is the safest way to take it? I hope I do not ruin my lungs or my nose by inhaling this crap. It feels like a big glob in the back of my throat.
 
Maybe there was something wrong with the pills...

whenever you took opana oraly and it didnt work AT ALL was it from the exact same source??? was it purchased from a dealer off the street???(or a friend, whoever, off the street is off the street)??? Because it could of been a bad batch, or fake pills. It hsa been known to happen.

And when you crushed up the opana pill and snorted it and it finally worked was that from the same source where you got the other ones??

All these things can make a difference.

But if it wasn't a problem with the pills....I would say its likely that you truly don't have the correct enzymes or whatever in your stomache that can properly break down opana so it can be metabolized.....this also isnt uncommon.

I personally do not have the right enzymes to break down alcohol...therefore whenever I drink I simply get horribly sick and throw up...well before I get any chance of being drunk....the doctors said it happens in one out of every like 30,000 people or something...

...so keeping that in mind...I can see how its possible that your missing an enzyme or for some reason arent able to break down opana to be properly metabolized.
 
You should definitely make very small lines and wait 10 minutes or so between each snorting (one line in each nostril). Otherwise it is going to gel up and not work as well. If you snorted that 40mg in 1 or 2 lines then I would start with like 10mg-20mg snorted efficiently. As for the "not taken as prescribed", that is understandable. But it is a personal issue, I have no problem taking the medicine as it works best for ME, as opposed to what the doctor says. They are not in my body and do not know what works and what doesn't.

Anyway, I came in here for another reason. Any luck in IV'ing these yet? I mean, if you can snort them in small amounts, couldn't I dissolve these in small amounts or something?
 
Maybe there was something wrong with the pills...

whenever you took opana oraly and it didnt work AT ALL was it from the exact same source??? was it purchased from a dealer off the street???(or a friend, whoever, off the street is off the street)??? Because it could of been a bad batch, or fake pills. It hsa been known to happen.

And when you crushed up the opana pill and snorted it and it finally worked was that from the same source where you got the other ones??

All these things can make a difference.

But if it wasn't a problem with the pills....I would say its likely that you truly don't have the correct enzymes or whatever in your stomache that can properly break down opana so it can be metabolized.....this also isnt uncommon.

I personally do not have the right enzymes to break down alcohol...therefore whenever I drink I simply get horribly sick and throw up...well before I get any chance of being drunk....the doctors said it happens in one out of every like 30,000 people or something...

...so keeping that in mind...I can see how its possible that your missing an enzyme or for some reason arent able to break down opana to be properly metabolized.

LOL!!

No, no, I am prescribed these every month by a doctor! I get them directly from a major chain of pharmacy stores. Trust me I know they are 100% real lol.

It must be some sort of enzyme because when I take them in mt mouth and swallow them they do not even keep me from getting sick.

Literally I can take 4-5 and still get withdrawal, and start sweating and freezing....

They DO NOTHING!!

Now I take the cover off and snort one and it feels exactly like my oxycodones!!

I was STUNNED by what happened after snorting it!! I was high as a kite, this was the first time I have ever in my life felt anything from an OPANA.

I guess my body cannot handle the pills for some reason - I have been on pain meds for like 6 years and this is the strangest things that has ever happened to me. I do not think it is oxymorphone but rather there may be something about that timerRX thing that my body cannot process.

I am still stunned to finally feel what an OPANA can do!!!
 
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