• BASIC DRUG
    DISCUSSION
    Welcome to Bluelight!
    Posting Rules Bluelight Rules
    Benzo Chart Opioids Chart
    Drug Terms Need Help??
    Drugs 101 Brain & Addiction
    Tired of your habit? Struggling to cope?
    Want to regain control or get sober?
    Visit our Recovery Support Forums
  • BDD Moderators: Keif’ Richards

O-Desmethyltramadol doasge question

frontbluntt

frontbluntt

Bluelighter
Joined
Apr 22, 2009
Messages
421
I have a very small amount of this, enough to give it a go only once and I don't want to be disappointed but I don't want to be puking all night either. What kind of dose should I take? (I take 30mg of hydrocodone)
 
I would take around 100mg....maybe try snorting 50, see where that gets you, and go from there...
 
It's difficult to say - as it's so new we don't have accurate conversion data or bioavailability data... going by personal experience and comparing it to other things, and your tolerance, I'd go with definitely no more than 50mgs, definitely don't mix it with other downers, and maybe consider even less and topping it up. You can insufflate it (again no idea on bioavailabilities; oral seems possibly a bit stronger in my experience) so that would allow for fairly easy titration as it hits pretty fast..

See if anyone else has anything different to say! :)

There is an o-desmethyltramadol thread on Other Drugs too, might be worth taking a look..
 
actually I started making a BA chart for this using user-reported equivalencies. Most people seem to find snorting about equal to plugging, and oral lower (in terms of BA) If you look at the molecule, it has many similarities to the -morphones which means that I would expect oral BA to be somewhere around 30-40%, snorted/ plugged around 50% and IV (obviously) 100%.

The data I have seems to support this.

IT seems to be about 3-4x weaker than morphine, so maybe 2-3x weaker than HC, so I would try 50mg and work up. You can always take more, but never any less.
 
Interesting, thanks mu! :) I hate subjective "hmmm it kinda feels like this to me" stuff (but that's all I've had to offer so far) so it'd be nice to get more of a consensus, especially one with some basis in pharmacology, for this drug..

50mgs sounds like a good starting dose then!
 
I don't understand why they don't start testing it clinically and get the ball on prescribing it. It's pro-drug fucking sucks.
 
without a bio-assay it is hard to tell what the exact BA's are, but I have data from like 20 people, and since some used IV, that gives a starting point you can work backwards from. I wouldn't be surprised if my data was withing =/- 5% of actual BA.
 
Indeed. Better than guestimating based on my own and a couple of mates experience. I did feel that oral might be slightly stronger but I must be honest, my current scales are terrible, so I would not be surprised it they are inaccurate! Plus the doses I tend to use involve a lot of insufflation and therefore some degree of waste.

Plugged being 50% ish sounds about right :)
 
Thanks for all the helpful answers! Looks like I will start with a 50mg insufflated dose and then work up. Anyone know from experience how long I should wait after snorting before deciding to do more? When I snort hydromorphone it usually takes 3-5 minutes for me to feel it completely so I assume this is quite similar?
 
I agree, you're going to need to have some interval here. Give yourself plenty of time and don't rush. 15 minutes should work just fine.
 
You must log in or register to reply here.
Top