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RCs O-Desmethyltramadol Bio-availability user survey. Please Help.

oral: 50mg
insufflation: 30mg
equivalent to: 120mg codeine, 40mg hydrocodone, or 100mg tramadol + 10mg diazepam
(no opioid tolerance assumed)

duration: long when dosed orally, even on an empty stomach, with the onset in 30-45 min. it hangs around for many hours (at least as long as regular tramadol, up to 6 or 8 hours for main effects). insufflation also lasts long, tho a bit shorter & with a more rapid onset (effects start maybe twice as quick? dunno for sure). burns slightly, but not too bad when crushed into a very fine powder.

Opioids I have done are kratom, codeine, buprenorphine, ethylmorphine, tramadol and this o-dtm.

By far I find this strongest, but then again it's very subjective.
Click to expand...

i haven't had ethylmorphine, but i've tried diacetylmorphine, morphine, pentazocine, dihydrocodeine, hydrocodone, and the others you mention as well. although with the morphine's i never had high doses or anything other than oral/insufflation.

and i agree that this is the one of the heaviest. it is powerful and sedating, has way more punch than regular tramadol.
 
Last edited:
perKeceT said:
^^^ 100mg of plain tramadol is equivilent to 40mg hydrocodone for you?
must be nice.
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ah, but i meant 100mg tramadol + 10mg diazepam (valium). but still, yeh, i'm pretty sensitive to vanilla tramadol! for me, tramadol also has a strong (serotonin?) uplifting aspect to it that hydro's don't have. 40mg of hydro's are stonier than 100mg plain tramadol, that's for sure, but if you throw in the 10mg valium i think they're pretty close.
 
I always heard that you get more of the drug effect, more of a buzz, or more of a high if you stacked intakes various lengths apart..... i guess the bio-availability goes up when you already have some in your system and blood / and its being processed / and/or digested than if you did your total dose all at once.....

I mean it worked like this for me when i had some , i guess it could have been a placebo effect but i always noticed it way more when i stacked it apart.....

Hope this helped.
 
These are very rough estimates

Without tolerance:

[BLANK] -Oral- | -Intranasal- | -Rectal- | -IV/IM/SC- | -Opiate MG
Dose|------------------------------150-250 mg-----------------300-450 mg codeine /10- 20mg oxy (orally)



Typical Recreational Dose: ~ 200-400 mg plugged /w tolerance
Highest Dose Taken: ~480 mg plugged /w tolerance
 
InterzoneAgent said:
[BLANK] -Oral- | -Intranasal- | -Rectal- | -IV/IM/SC- | -Opiate MG
Dose|------------------------------150-250 mg-----------------300-450 mg codeine /10- 20mg oxy (orally)
Click to expand...

According to this the O-DMT is less powerful than the Tramadol. You could compare to the Tramadol.
 
Aleph said:
According to this the O-DMT is less powerful than the Tramadol. You could compare to the Tramadol.
Click to expand...

There is bad batch of o-dmt going around that isn't even o-dmt, it might be regular tramadol.

I have experience from (two different sources, both legit) o-dmt and tramadol and I can certainly say that o-dmt is about 2-3x more potent, at least for me. 150mg regular tramadol gives me nice opioid high.

I have found for myself a sweet spot for this substance, 30-40mg plugged o-dmt gives me nice warm high for 4-5h, but without going too confusing. I have found that high doses of o-dmt gives me speaking problems, aphasia and nausea. From wikipedia: aphasia is also listed as a rare side effect of the fentanyl patch, an opioid used to control chronic pain. So it seems it is also rare side effect of o-dmt.

I have plugged around 10mg MXE before or sometimes same time with o-dmt. It seems to prevent tolerance build up and boosts its effects. I also eat 425mg magnesium malate (best BA) and lots of different vitamins, antioxidants and omegas every day and exercise five days a week. So I think these also helps prevent tolerance build up. I have theory that exercising will slow up opioid tolerance, because you get opioid activity from endorphine. I've done codeine, o-dmt and kratom about every other weekend, usually friday-saturday for little over half year now, sometimes having one or two months tolarance break and it seems that tolerance rises pretty slowly.
 
Ne0 said:
There is bad batch of o-dmt going around that isn't even o-dmt, it might be regular tramadol.

I have experience from (two different sources, both legit) o-dmt and tramadol and I can certainly say that o-dmt is about 2-3x more potent, at least for me. 150mg regular tramadol gives me nice opioid high.

I have found for myself a sweet spot for this substance, 30-40mg plugged o-dmt gives me nice warm high for 4-5h, but without going too confusing. I have found that high doses of o-dmt gives me speaking problems, aphasia and nausea. From wikipedia: aphasia is also listed as a rare side effect of the fentanyl patch, an opioid used to control chronic pain. So it seems it is also rare side effect of o-dmt.

I have plugged around 10mg MXE before or sometimes same time with o-dmt. It seems to prevent tolerance build up and boosts its effects. I also eat 425mg magnesium malate (best BA) and lots of different vitamins, antioxidants and omegas every day and exercise five days a week. So I think these also helps prevent tolerance build up. I have theory that exercising will slow up opioid tolerance, because you get opioid activity from endorphine. I've done codeine, o-dmt and kratom about every other weekend, usually friday-saturday for little over half year now, sometimes having one or two months tolarance break and it seems that tolerance rises pretty slowly.
Click to expand...


thats explanes why mine was so shit last week told supplier he got in an arse said it was fine was it bollocks like
 
Ok, yesterday ended up my 2 week O-desmethyltramadol daily use, and it seems MXE and magnesium really helps with tolerance build up. I usually plugged 70mg before work and 50mg after work. Surely I didn't nod, that I almost do in higher doses like 120mg. I never have been really into opioid nodding, I like the calming and good focusing effects which I get from o-dmt.
 
Guys, please, there is already a general tramadol thread. Posts in this should relate to Bioavailability, preferably in the format I gave. I still don't have enough data points to get reliable relative BA's.
Please, just fill out my little form from the first post.
 
[BLANK] -Oral- | -Intranasal- | -Rectal- | -IV/IM/SC- | -Opiate MG
Dose|----N/A-------N/A---------300--------N/A-------200mg oral morphine/30mg IV Homebake heroin

I'll probably try and report on smoking and potentially IV/IM. I'm not gonna waste a bunch on oral and my sinuses can't handle snorting shit (it's a question of smoking cigarettes/spliffs and thus never being able to breath through my nose- how the fuck do you other chain smokers snort shit?), so that isn't gonna happen. Speaking of needleplay, my desmethyltramadol dissolves fine in water (sterile water from needlebank)- 90% of it dissolves on contact with water, with the remaining grains dissolving with a bit of stirring (no heat required). It also seems to dissolve at very high concentrations- 1ml can only hold 60mg of morphine, but I dissolved around 120mg of desmethyltramadol in 0.5ml without any hassles.

Thus far it seems to be quite similar in potency to pethedine. However the high is nothing like morphine/heroin, it has a different body load, a less satisfying sedation and nowhere near the same level of euphoria as morphine. I also am sensing a bit of a ceiling, around the 500mg-ish mark where the effects don't get any stronger, you're simply maintaining your current state. That may help with the overdose liability...
 
Mod note: I cleaned up the thread a bit (including some of my own OT replies)

Thanks to everyone who has contributed! Please, if you have an O-DMTramadol experience or know another bluelighter who uses it and hasn't posted here, recruit them and keep feeding me data... the distribution has been getting tighter and tighter when the points are plotted...
 
never tried this drug but it seems like best bioavai route is iv (duh) followed by rectal, nasal and finally oral. although nobody has mentioned IM if it causes muscle wasting or infection. need more responses though from the community
 
Using the data presented in this thread, as well as any anecdotal reports I could find on the topic from other sources, I computed weighted averages structured to minimize the impact of data point outliers in calculating approximate bioavailability for the common routes of administration. Because of the small sample size, values are given to the nearest ten percent, but by chance, the unrounded average values I calculated deviated by no more than 2.1% from the rounded values given below.

Oral -- Intranasal -- Intrarectal -- Intravenous

40% -- 60% -- 70% -- 100%
 
mydrugbuddy said:
All very interesting. But can anybody, anywhere get hold of any of this stuff >? It's rarer than hen's teeth.
Click to expand...

We can't go into specifics as per the Bluelight User Agreement, sorry, but last I checked no one was manufacturing it let alone in anything close to a reputable manner, so I think we'll find out if/when people start posting about it. I know that it's been quite some time now that o-desmethyltramadol has been generally unavailable. =\
 
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