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Novel stimulant compounds (perhaps with less spam than the 'stims of the future')

bzp might be an alternative for people with a compulsive stimulant habit.
regarding safety, desoxypiradol and all these 'novel' stimulants wont be better than plain old meth in the hands of a speedfreak.

at the moment i can only imagine desoxypipradols effects and from what i've read a stimulant with duration and intensity of effects between these of metylphenidat and desoxypipradol would be almost perfect.

does anybody know pipradols therapeutical dosage?
 
5meo-pete said:
bzp might be an alternative for people with a compulsive stimulant habit.
regarding safety, desoxypiradol and all these 'novel' stimulants wont be better than plain old meth in the hands of a speedfreak.
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Depends... IME, MDPV and methylone are better than meth in anyone's hands, period. But desoxypipradrol is pure evil in the hands of a compulsive user, as (to a lesser extent) is diphenyl prolinol.
 
maybe only because it needs longer to become wasted enough ;>

mdpvs effects felt somewhat dirty when compared to other daris. it lacked this clear, focussed feeling that can become a manic episode and therefore could be regarded as relatively benign.
might be related to the carbonyl group and the ring substitution pattern.

are the known 1-pheny,2-pyrrolidinylalkans pure reuptake inhibitors whithout releasing properties?
 
5meo-pete said:
maybe only because it needs longer to become wasted enough ;>

mdpvs effects felt somewhat dirty when compared to other daris. it lacked this clear, focussed feeling that can become a manic episode and therefore could be regarded as relatively benign.
might be related to the carbonyl group and the ring substitution pattern.
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I know we (as researchers) are often lacking in tools/resources, but I don't have a clue how you could reach such conclusions, even tentatively, from a few casual and subjective experiments. Color me lost on that one.
 
Seriously- you're drawing conclusions from scratches in dirt. There's no way to extend what's known to the sort of claims you try to make.
 
Personally, I hated the effects of MDPV. It seemed similar to methylphenidate in effect and duration (read: short), but with even more annoying peripheral sides. It failed to provide me with mental focus or the desired anti-ADD or anti-depressant effects; instead it just gave me a headache, jacked up my sympathetic nervous system and made me feel all 'hot and bothered,' like drinking 8 or so shots of espresso at once.

In fact, I really don't particularly enjoy beta-keto-amphetamines in general. Perhaps cathinone itself would be better, as it is still a catecholamine releaser, rather than a reuptake inhibitor. I don't think that it is possible to make such a broad conclusion like the claim (above) that the beta-keto moiety gives a compound a gentler and subtler effect. People react in different ways to the same compound: different strokes.
 
^^ The first paragraph above reminds me of my first impression of 2C-B-BZP. The next night I tried a small dose of it again and noted euphoria instead. Stimulants change character on a dime, at least IME... I tend not to draw conclusions early anymore. I'm not even sure how many of their effects are due to placebo... probably a substantial proportion at any given time.
 
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Not a drug in itself but the combination of L deprenyl and methylphenidate produce's this crazy manic high like you wouldn't believe
 
substitution patterns that work with phenethylamines (2,5 dimethoxy, 4-halo) won't work with BZP because it binds in a fashion more analagous to cocaine.

here's a whole bunch of novel stims i'd like to synth and try

gt1: stimulant with a novel ring system. the lone pair on the N is twisted to a different conformation.

gt2: bzp with a carboxymethyl group.

gt3: bzp with a keto group.

gt4: another stim with a novel ring system.

gt5: phenmetrazine with the methyl group location swapped. could be a good way to circumvent analogue laws
 

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g2 is
not BZP with a carboxymethyl group. That is MBZP with a carboxymethyl group.
ie. 2-methylcarboxy-1-benzoylpiperazine.
Nor is g3 BZP with a keto group.
That is MBZP with a keto group.
ie. 1-methyl-4-benzoylpiperazine.
 
Ham-milton said:
does gt4 have a name? I've never seen it.
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1-benzyl-7-azanorbornane
or

1-benzyl 7-azabicyclo[2.2.1]heptane

it is very close to epibatidine type nicotinic agonists structurally.

I think FnB's grand chart of stimulant anorexics had this structure in it.

the quinuclidine version of gt1 is a known thing and is a low potency anorectic.

I have not seen any information as to how BZP binds, to DAT or whatever. but it is more likely to bind in a manner similar to the GBR compounds than cocaine.
 
^^^^

I think FnB's grand chart of stimulant anorexics had this structure in it.



Is this chart on this site and if so if not too much trouble can you provide the link....?

Thanks
 
LuxEtVeritas said:
^^^^

I think FnB's grand chart of stimulant anorexics had this structure in it.



Is this chart on this site and if so if not too much trouble can you provide the link....?

Thanks
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its an image. I think I have seen it on this site, TFSE is useless in locating it.
originally I remember it from the hive.
 
Riemann Zeta said:
Also, I would like to open up the floor to anyone would has tried one of the particular rare gems of the stimulant world. For example, prolintane ([N-pyrrolidyl]-alpha-ethyl-phenethylamine)
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How rare is prolintane? The Wikipedia article reports it being used in European countries, but we all know about Wikipedia's (sometimes) lack of accuracy. Anyone know?
 
Prolintane is good stuff - even gives a weird sort of munchies! Only had it a few times, but is well woth persuing IMO (although not as much as fencamfamine, but then what is? =D)

For example, prolintane ([N-pyrrolidyl]-alpha-ethyl-phenethylamine)
Click to expand...

It's actually alpha-propyl (a 5 carbon side chain, like pyrovalerone & MDPV)


I'll try and find the big charts of all the stimulants I posted at the hive & post them here. They used to be in my gallery, but I'm not sure if I removed them when we were lomited to 15 pictures
 
Ah, prolintane does have an alpha-propyl moiety, my mistake. I think it does count as a rare stimulant, as it is no longer available in most countries that it was originally used in. I believe the wikipedia information is simply outdated--I think that it was freely available in the 1990s, but is no longer on the market (at least, as an OTC med or research chemical).
 
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