jasoncrest
Bluelighter
- Joined
- Sep 15, 2003
- Messages
- 3,952
ebola? said:So...do we have a basis as to speculate about what sigma agonism might do?
ebola
Yes, we know what sigma agonists do (but according to Wikipedia only):
1. "Noscapine (Nospen) has a history of Over-the-counter drug abuse in a several countries being readily available from local pharmacies as a prescription drug. The effects, beginning around 45 to 120 mins after consumption, are similar to dextromethorphan and alcohol intoxication."
So, effects like alcohol and DXM, and maybe recreationnal (cause of the common abuse of it in the countries where it is commercilaized)
2. "Side-effects:
* Loss of coordination
* Hallucinations (auditory and visual)
* Loss of sexual drive
* Swelling of prostate
* Loss of appetite
* Dilated pupils
* Increased heart rate
* Shaking and muscle spasms
* Increased alertness
* Loss of any sleepiness
* Loss of stereoscopic vision"
So it seems like it's more of a stimulant than a downer (Increased alertness, Loss of any sleepiness, Increased heart rate, Loss of appetite)
And that it causes intoxication ( Loss of coordination, Hallucinations (auditory and visual)
P.S. are there other Sigma agonists commercialized?