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Nootropics/OTC supps to enhance THERAPUETIC action of amphetamines.

I

ib_PYRO

Greenlighter
Joined
Nov 19, 2013
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I am currently taking 30 mg vyvanse, along with lexapro, trazodone, and low dose benzos. I would like to keep the amphetamine dose as low as possible while remaining effective. I take an absorbable zing/Mg/B 6 supplement every night and a B and D vitamin supps in the morning, from my research these seem to be the most useful vitamins to supplement with. I am especially curious about the racetams, thiamine derivatives like Sulbutiamine, and adrafinil. Or anything that is cheap and easily available (not just thru RC sites). Again I don't care about increasing recreational effects just concentration, wakefulness, motivation, and delaying tolerance.

I have done research on various nootropics but it seems there are conflicting theories as to how they work. I was wondering if there is any newer, more reliable data. Have read about piracetam enhancing communication between the brain's hemispheres, increasing Ach transmission, effects on NMDA glutamate receptors. I have also read claims that it helps with everything from learning, depression, bipolar mania, as well as potentiating most drugs with no side effects. I'm always skeptical of such claims. I've tried it in the past however I was also drinking heavily at the time so I can't really draw conclusions about it, but I didn't really notice much. Seems to me that if it really potentiated the effects of so many drugs I would have found info about dangerous interactions.

Any insights or links would be appreciated.
 
I should add I've read theories about DXM preventing tolerance however I am on SSRIs and feel spacey in an unpleasant way at 60 mg. Plus DXM seems to have a wide variety of effects on brain circuits and its use for this purpose is not well researched so I think it would be best avoided.
 
The long and short of it is there's no magic pill you can take to make amphetamine work forever. Regular usage will eventually lead to tolerance.

Any benefit you get from the nootropics you will probably notice without taking amphetamine...
 
Not too sure on the tolerance side, but PRL-8-53 synergizes with amphetamines; there's discussions on another forum stacking it with several racetam and amphetamines that produced good results. Modafinil does synergize, sort of in a different way; sort of levels off the entire dose so there is very little rush and very little comedown.
 
You could always just add a DNRI to increase serum concentrations made by the agonist itself. I was once on wellbutrin alongside adderall. Or even ritalin, but it seems you're looking for less synthesized formulations.
 
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